A5100619065- Bone Metabolism and Diseases
- Prostate Cancer Treatment and Research
- Circular RNAs in diseases
- FOXO transcription factor regulation
- Advanced Proteomics Techniques and Applications
- RNA Research and Splicing
Second Military Medical University
2019
Changhai Hospital
2019
Abstract Iron overload is a common stress in the development of cells. Growing evidence has indicated that iron associated with osteoporosis. Therefore, enhancing understanding would benefit novel approaches to treatment The purpose present study was analyze effect on osteoblast cells, via MC3T3‐E1 cell line, and explore its possible underlying molecular mechanisms. Ferric ammonium citrate (FAC) utilized simulate conditions vitro. FAC‐induced strongly suppressed proliferation cells induced...
Ghrelin (GHRL) is a polypeptide that can specifically bind to the growth hormone secretagogue receptor (GHSR). The expression of GHSR significantly different in normal and prostate cancer (PC) tissues humans. It important find an effective diagnostic method for diagnosis prognosis invasive PC/neuroendocrine (NEPC).GHRL mRNA levels were determined by quantitative real-time polymerase chain reaction PC tissues. GHRL proteins was assessed Western blot assay immunohistochemistry. A probe...