Larissa Lührs

ORCID: 0000-0001-6967-735X
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About
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Research Areas
  • Mesenchymal stem cell research
  • Cardiac Fibrosis and Remodeling
  • Adipose Tissue and Metabolism
  • Nuclear Receptors and Signaling
  • Cancer Diagnosis and Treatment
  • Multiple Sclerosis Research Studies
  • RNA regulation and disease
  • MicroRNA in disease regulation
  • Neurogenesis and neuroplasticity mechanisms
  • Cardiovascular Function and Risk Factors

The therapeutic effect of stem cells is attributed to their direct maturation into somatic and paracrine effects, which influence the extracellular environment. One such component released vesicles containing proteins genetic materials with immunomodulatory functions facilitating cell-to-cell communication. study's main objective was characterize (EVs) from Human Neural Precursor Cells (hNPCs). Wharton's Jelly mesenchymal (WJ-MSCs) were isolated by explant technique characterized flow...

10.2147/ijn.s502031 article EN cc-by-nc International Journal of Nanomedicine 2025-05-01

This study aims to evaluate and compare cellular therapy with human Wharton’s jelly (WJ) mesenchymal stem cells (MSCs) neural precursors (NPs) in experimental autoimmune encephalomyelitis (EAE), a preclinical model of Multiple Sclerosis. MSCs were isolated from WJ by an explant technique, differentiated NPs, characterized cytometry immunocytochemistry analysis after ethical approval. Forty-eight rats EAE-induced myelin basic protein Freund’s complete adjuvant. hours later, the animals...

10.3390/ijms25136996 article EN International Journal of Molecular Sciences 2024-06-26

This systematic review describes the most common methodologies for immortalizing human and animal mesenchymal stem cells (MSCs). study follows rules of PRISMA is registered in Institutional Review Board PROSPERO International reviews, numbered protocol code: CRD42020202465.

10.2174/011574888x268464231016070900 article EN Current Stem Cell Research & Therapy 2023-12-01
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