Abstract Background Chronic kidney disease (CKD) and acute decompensation of CKD (ACKD) are common in cats. Objectives To characterize the etiology, clinical clinicopathologic findings, short‐ long‐term prognosis feline ACKD. Animals One hundred cats with Methods Retrospective study, search medical records for Results Common signs included anorexia (85%), lethargy (60%), weight loss (39%), vomiting (27%). Suspected etiologies ureteral obstruction (11%), renal ischemia (9%), pyelonephritis...

Abstract Background Chronic kidney disease (CKD) and acute exacerbation of CKD (ACKD) are common in dogs. Objective To characterize the etiology, clinical laboratory findings, short‐ long‐term prognosis dogs with ACKD. Animals One hundred Methods Medical records diagnosed ACKD admitted to a veterinary teaching hospital were retrospectively reviewed. Results The most signs included anorexia (84%), lethargy (77%), vomiting (55%) diarrhea (37%). Presumptive etiology inflammatory causes (30%),...

Antithrombin (AT) is the major inhibitor of coagulation. In people, hypoantithrombinemia associated with hypercoagulability, thrombosis, and poor prognosis. Veterinary studies, however, have not demonstrated similar prognostic significance. Thus, AT activity (ATA) in dogs currently interpreted based on human medicine guidelines.ATA can serve as a marker dogs, has been shown people.(1) To describe clinical clinicopathologic findings, diagnoses, outcome decreased versus normal ATA, (2) to...

Background Pancreatitis in cats (FP) has been increasingly diagnosed recent years, but clinical studies of large numbers affected are scarce. Objectives To describe a cohort with FP requiring hospitalization. Animals One hundred and fifty‐seven client‐owned cats. Methods Retrospective study, including pancreatitis based on sonographic evidence, positive SNAP feline pancreatic lipase immunoreactivity test results, increased 1,2‐o‐dilauryl‐rac‐glycerol‐glutaric Acid‐(6′‐methylresorufin...

Members of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex cause severe outbreaks in humans, and are increasingly reported animals.A retrospective study, describing a outbreak dogs cats caused by multidrug resistant member veterinary hospital, between July 2010 November 2012.The study included 19 4 cats. bacteria were isolated from urine (9 animals), respiratory tract (11), tissues (3) blood (1). The most common infection-associated findings fever, purulent discharge...

Feline hepatic lipidosis (HL) is a common, potentially life-threatening disease resulting from prolonged anorexia and increased catabolism. This retrospective study included cats diagnosed with HL based on liver cytology or histopathology (years 2004-2015), aimed to identify clinical laboratory parameters associated mortality. The 71 (47 females 24 males) 85 control non-HL diseases. Most (90 per cent) were mixed breed, neutered (70; 99 cent), female (47; 66 indoor (56; 79 fed dry commercial...

Dogs with protein-losing enteropathy (PLE) are suggested to be at increased risk of developing thromboembolic events. However, some exceptions, there very few reports thromboembolism in such dogs. This multicentre retrospective observational study describes a case series (TE) eight dogs PLE secondary non-neoplastic, chronic small intestinal disease. Seven had poorly controlled when the event occurred. Pulmonary (PTE) occurred six dogs, while one dog developed splenic vein thrombosis and...

Background Current recommendation for performing the ACTH stimulation test (ACTHST) diagnosis of hyperadrenocorticism (HAC) advocates collection baseline serum cortisol concentration (BC), but no references interpretation its results exist. Objective Evaluate contribution BC ACTHST to HAC. Animals Fifty‐four dogs were evaluated suspected HAC at a referral hospital. Methods Records that had been by reviewed. Receiver operator characteristics (ROC) analyses used assess performance BC,...

Abstract Background Acute pancreatitis (AP) presumably is associated with pancreatic protease activation, inhibitor (PI) depletion, and inflammatory mediator secretion. Objectives Examine PIs concentrations in dogs AP their association death. Animals Thirty‐one diagnosed based on clinical signs, ultrasonographic findings, increased canine lipase immunoreactivity (cPLI) 51 healthy control dogs. Methods Antithrombin α 2 ‐antiplasmin activity (ATA AP, respectively) of 1 ‐proteinase (α PI),...

Procalcitonin is considered an acute phase protein used as both a marker of infection and prognosis in human medicine. Canine procalcitonin has been previously sequenced; however, its use diagnostic or prognostic tool dogs never assessed. A quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay for canine messenger RNA (mRNA) was developed. Whole blood samples were collected from ill healthy dogs. extracted the realtime PCR The patients' diagnoses, complete cell count,...

Background Acute pancreatitis (AP) is common in dogs. Nevertheless, validated clinical severity index (CSI) scoring systems to assess and guide treatment current, large‐scale studies are unavailable. Methods This a retrospective study including 109 Pancreatitis was diagnosed based on signs, abdominal sonographic evidence, positive pancreatic lipase assays experts’ assessment consensus. Results The survival rate 75 per cent (82 dogs). Azotaemia presence of local complications (ie, ascites)...

Fading puppy syndrome (FPS) is a fatal condition in neonatal dogs. Intestinal microbial alterations, although never investigated, may be involved its pathophysiology. The study examined the occurrence of FPS and associations with dam, puppy, husbandry characteristics, compared intestinal diversity healthy puppies those FPS, whether microbiomes are predictive FPS. Day 1 8 post-partum (PP) rectal swabs were collected from which later developed Microbial compositional structure, including alpha...

Abstract Background The utility of 1,2‐o‐dilauryl‐rac‐glycero glutaric acid‐(6′‐methylresorufin)‐ester‐(DGGR)‐lipase activity (DLA) in monitoring clinical progression chronic pancreatitis (CP) dogs is unknown. Objective To examine the association DLA with signs CP, as assessed by a CP severity score (CPCSS). Animals: Twenty‐four dogs. Methods This retrospective study. Chronic was diagnosed based on and > 250 U/L monitored using CPCSS DLA. Results study included 134 visits (median, 10...

Abstract Background Giardia duodenalis (Gd) causes intestinal parasitosis. The involvement of the microbiome in determining infection's clinical phenotype is unknown. Objective Investigate fecal features dogs with giardiasis. Animals and Methods Cross‐sectional study, including samples kenneled Gd diagnosed by antigen dot ELISA. microbial compositional characteristics dysbiosis index (DI) were compared between diarrheic nondiarrheic dogs. Results Fecal 38 Gd‐infected (diarrheic, 21;...

A 6-month-old domestic shorthair female cat was presented with suspected diaphragmatic hernia (DH) that later confirmed by thoracic radiography. The underwent exploratory celiotomy a rupture (DR) repair and recovered. Six days later, it represented vomiting anorexia. Megaoesophagus (MO) gastric dilatation were diagnosed contrast second revealed no abnormalities gastropexy performed. Endoscopy demonstrated MO, oesophagitis gastro-oesophageal reflux. MO persisted for several weeks an...

Abstract Background Copper‐associated chronic hepatitis (CuCH) is poorly characterised in Cavalier King Charles spaniels (CKCS). Methods Hepatic copper accumulation was qualitatively and quantitatively assessed, blood samples were used for genetic testing to screen known CuCH‐associated variants. Results The study included 13 CKCS with CuCH eight unaffected controls. Increased transaminase activities, elevated biliary enzyme concentrations portal hypertension documented 100%, 73% 38% of dogs...

Renal disease is considered the main cause of natural mortality in dogs with canine leishmaniosis. The pathological mechanisms associated kidney injury leishmaniosis include immune complex glomerulonephritis, tubulointerstitial nephritis and occasionally renal amyloidosis. Proteinuria a frequent finding its quantification by urine protein-creatinine ratio (UPC) an important parameter staging lesihmaniosis as presented LeishVet group.A 4.5 year-old spayed female Belgian Malinois dog was to...

Abstract Dirofilaria repens is a parasitic nematode in the subcutaneous tissue of carnivores, including dogs and cats, transmitted by mosquitoes. Human beings may be accidental hosts. Infection dog with D was first reported Palestine 1934, 2 additional cases were Israel to date. This report describes infection 4 that presented masses, which cytologically characterized marked mast cell eosinophil infiltration. In 3 cases, multiple microfilariae present lesions; rare th case. all dogs, PCR...

A 2.5-year-old castrated male cat presented with fever and marked generalized lymphadenopathy of 4-months duration, despite treatment amoxicillin-clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, FIV/FeLV test apart from a borderline, non-regenerative anemia. Peripheral lymph node fine needle aspirations revealed increase in the percentage intermediate- lymphoblastic-lymphocytes addition to reactive macrophages. Three weeks after...

The long-term clinical and biofhemical effects of basal-bolus insulin treatment with lispro NPH in dogs diabetes mellitus are undocumented.To perform a prospective pilot field study the on signs serum fructosamine concentrations (SFC) mellitus.Twelve received combined insulins twice day were examined every 2 weeks for months (visits 1-4), 4 up to additional 5-8). Clinical SFC recorded at each visit. Polyuria polydipsia (PU/PD) scored as absent (0) or present (1).Median (range) PU/PD scores...