Д. К. Обухов

ORCID: 0000-0001-7233-0752
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Research Areas
  • Neurogenesis and neuroplasticity mechanisms
  • Atrial Fibrillation Management and Outcomes
  • Zebrafish Biomedical Research Applications
  • Functional Brain Connectivity Studies
  • Cardiac Arrhythmias and Treatments
  • Physiological and biochemical adaptations
  • Axon Guidance and Neuronal Signaling
  • Sulfur Compounds in Biology
  • Advanced Neuroimaging Techniques and Applications
  • Human Health and Disease
  • Neurological Disorders and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Fish Ecology and Management Studies
  • Neonatal and fetal brain pathology
  • Aquaculture Nutrition and Growth
  • MicroRNA in disease regulation
  • Fusion and Plasma Physics Studies
  • Pregnancy and preeclampsia studies
  • Fish Biology and Ecology Studies
  • Technology and Human Factors in Education and Health
  • Traumatic Brain Injury Research
  • Anesthesia and Neurotoxicity Research
  • Hydrogen's biological and therapeutic effects
  • Neuroscience of respiration and sleep
  • Antiplatelet Therapy and Cardiovascular Diseases

St Petersburg University
2007-2023

Uppsala University
2021-2022

Liverpool Heart and Chest Hospital
2022

Associazione Nazionale Medici Cardiologi Ospedalieri
2022

Örebro University
2022

University of Liverpool
2022

Aalborg University
2022

Carol Davila University of Medicine and Pharmacy
2021-2022

A.V. Zhirmunsky National Scientific Center of Marine Biology Far Eastern Branch of the Russian Academy of Sciences
2012

We investigated the distribution of gamma aminobutyric acid, tyrosine hydroxylase and nitric oxide-producing elements in a cherry salmon Oncorhynchus masou brain at various stages postnatal ontogenesis by immunohistochemical staining histochemical staining. The periventricular region cells exhibited morphology neurons glia including radial glia-like contained several neurochemical substances. Heterogeneous populations hydroxylase-, acid-immunoreactive, as well nicotinamide adenine...

10.3969/j.issn.1673-5374.2013.01.002 article EN PubMed 2013-01-05

In the brain of teleost fish, radial glial cells are major type astroglial cells. To answer question as to how glia structures adapt continuous growth brain, which is characteristic salmonids, it necessary study various types (neuronal precursors, cells, and in a state neuronal differentiation) integrative centers salmon (telencephalon tectum opticum), using rainbow trout, Oncorhynchus mykiss, model. A distribution several molecular markers telencephalon with identification neural...

10.3390/ijms23031188 article EN International Journal of Molecular Sciences 2022-01-21

The distribution of proliferative zones, NO-producing cells and apoptosis areas in the medulla oblongata, cerebellum, optic tectum, thalamus hypothalamus Amur sturgeon Acipenser schrenckii was investigated, using techniques immunoperoxidase staining proliferating cell nuclear antigen (PCNA), neuronal nitric oxide synthase TU-NEL-labeling fragmented DNA. It has been established, that brain NO can act both as a cytotoxic proapoptogenic factor, which stimulates proliferation. presence elements...

10.4236/abb.2012.326099 article EN Advances in Bioscience and Biotechnology 2012-01-01

The data of our investigations contribute to understanding cellular mechanisms the teleost fishes CNS forming in postembryonic development. revealed peculiarities structural and neurochemical organization description basic histogenetic processes (proliferation, migration neuronal cell differentiation) during brain fish, which have signs fetal organization, widen existing knowledge about histogenesis these structures It seems conceivable, that postembrional development some neurotransmitters...

10.4236/eng.2012.410b020 article EN Engineering 2012-01-01

Brain anatomy and structure, composition of the neurons, cytoarchitectural maps were compared between five species Acipenser, one Huso two Scaphirhynchus. Morphological differences in forebrain structure genera apparent. The evolutionary history Acipenseridae has been marked by an extensive mosaic radiation development inner their brains. Members Scaphirhynchus have a very simple telencephalon differing significantly from that Acipenser. It is clear neuromorphological variation sturgeon will...

10.1111/j.1439-0426.2007.00907.x article EN Journal of Applied Ichthyology 2007-07-23

Anatomy, cytoarchitecture and neuronal composition of the i everted-type telencephalon various sturgeon species; (Acipenser baeri Br., Acipenser stellatus Pall., nudiventris Lov., ruthenus L., gueldenstaedtii Huso huso L.) were studied by classical histological methods TV-imaging. Hemisphere was significantly variable across species genus, while neurone proved to be rather conservative. Neurones mainly undifferentiated, isodendritic type. The question homology structures between everted...

10.1111/j.1439-0426.1999.tb00214.x article EN Journal of Applied Ichthyology 1999-09-01

Objective – the study of age-related changes in neural groups cerebral cortex and cerebellar process upward ontogenesis. Material methods . The work was done on post-mortal material (75 left hemispheres, 62 cerebellum) obtained from children birth to 12 years old who died as a result injuries without damage brain. Using computer morphometry Nissl stained frontal histological sections taken layer III fields 8, 6o р 37ac, well granular paramedian lobule (H VII B), area group section total...

10.18499/2225-7357-2019-8-4-42-48 article EN cc-by Journal of Anatomy and Histopathology 2019-12-24

BACKGROUND: Human posterior associative cortex, including its temporoparietal–occipital subarea, is important in cognitive control, verbal activity, sensory stimuli processing, and attention regulation, visuomotor responses, situational decision making. Despite data suggesting the prolonged formation of these higher mental functions during postnatal ontogeny, cortex has been insufficiently characterized with respect to microstructural transformations individual functionally specialized zones...

10.17816/morph.562844 article EN cc-by-nc-nd Morphology 2023-10-06

Objective – the study of age-related changes in thickness cortex and its layers posterior lobe cerebellum children. Material methods. The work is performed on postmortem material (62 cerebellum), obtained from children aged birth to 12 years who died as a result injuries without brain damage. Using computer morphometry painted method Nissle frontal histological sections cortex, taken region right left quadrangular lobules (H VI) top folia cerebellum, was measured cortical molecular granular...

10.18499/2225-7357-2018-7-4-88-93 article EN cc-by Journal of Anatomy and Histopathology 2019-01-11
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