A5023977000- Pancreatic and Hepatic Oncology Research
- Cancer and Skin Lesions
- Electrospun Nanofibers in Biomedical Applications
- Breast Lesions and Carcinomas
- Tissue Engineering and Regenerative Medicine
- Glioma Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Breast Cancer Treatment Studies
- Management of metastatic bone disease
- Pancreatitis Pathology and Treatment
- Central Venous Catheters and Hemodialysis
- Economic and Financial Impacts of Cancer
- Social Media in Health Education
- Infective Endocarditis Diagnosis and Management
- DNA Repair Mechanisms
- Cardiac Valve Diseases and Treatments
- Healthcare Systems and Reforms
- Health Literacy and Information Accessibility
- Cardiac pacing and defibrillation studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pharmaceutical Economics and Policy
- Aortic Disease and Treatment Approaches
- Cancer survivorship and care
- Advances in Oncology and Radiotherapy
- Histone Deacetylase Inhibitors Research
Nationwide Children's Hospital
2024-2025
The Ohio State University Wexner Medical Center
2021-2025
The Ohio State University
2024
University of Michigan
2018-2020
Mutant IDH1 coexpressed with inactivating TP53 and ATRX mutations in glioma enhances DNA repair, causing resistance to genotoxic therapies.
We determined the availability and pricing of laboratory testing in Northern Region Ghana to identify current gaps with respect WHO's Essential Diagnostics List (EDL).A representative sample facilities offering diagnostic within was geographically mapped evaluated, random sampling stratified by population density. Data were collected on menus, volumes, turn-around times, out-of-pocket test prices. A total 27 health centers 39 clinical laboratories surveyed between June August 2019.Health...
Abstract Background The role of neoadjuvant therapy (NT) for ampullary carcinoma (AC) has not been clearly established. Methods Patients who underwent pancreatoduodenectomy AC between 2004 and 2016 were identified in the National Cancer Database. Overall survival (OS) was compared those received NT before resection surgery first (SF). Propensity score matching (PSM) performed using age, pathologic T N stage, tumor differentiation. Results Among 8688 patients with AC, 175 (2.0%) surgery....
Central MessageAlthough the B-SAFER procedure has its advantages, standard care remains open repair for dTAA or TAAA due to chronic aortic dissection.See Commentaries on pages 61 and 63. Although dissection. See The branched single anastomosis frozen elephant trunk (B-SAFER) includes partial arch replacement, a stent graft placed at zone 2 arch, small into left subclavian artery through graft.1Roselli E.E. Idrees J.J. Bakaeen F.G. Tong M.Z. Soltesz E.G. Mick S. et al.Evolution of simplified...
Advanced age is considered a risk factor for lung transplantation (LTX). We sought to evaluate the long-term outcomes of LTX in septuagenarian.LTX recipients UNOS transplant registry (May 1, 2005-June 12, 2020) were stratified into 18-59, 60-69, and > = 70 years age. Recipient characteristics evaluated survival, cause death (COD), length stay (LOS), complications. A Kaplan-Meier analysis examined survival all patients by age, specifically looking at death.A total 27 632 identified. As aged,...
Sentinel lymph node mapping in patients with axillary breast carcinoma is technically challenging and poorly described the literature. We report a patient primary ectopic of axilla whom concurrent peri-tumoral intra-tumoral injection radionuclide tracer allowed for identification biopsy sentinel nodes.
One sentence summary Mutant IDH1 acts as a tumor suppressor when co-expressed together with TP53 and ATRX inactivating mutations in glioma, inducing genomic stability, DNA repair resistance to genotoxic therapies. Abstract Glioma patients whose tumors carry mutation the Isocitrate Dehydrogenase 1 (IDH1 R132H ) gene are younger at time of diagnosis survive longer. The molecular glioma subtype which we modelled, harbors , protein 53 (TP53) alpha-thalassemia/mental retardation syndrome X-linked...
Background: The Fontan surgery for treating hypoplastic left heart syndrome has significantly improved postoperative mortality. However, the materials commonly used conduits, such as PTFE, can cause complications, graft calcification over long-term follow-up, which causes flow restriction and lower exercise tolerance clinical complications. To address these issues, we have developed a tissue-engineered vascular (TEVG) composed of biodegradable polymers that are replaced by autologous tissue,...
Sentinel lymph node mapping in patients with axillary breast carcinoma is technically challenging and poorly described the literature. We report a patient primary ectopic of axilla whom concurrent peri-tumoral intra-tumoral injection radionuclide tracer allowed for identification biopsy sentinel nodes.