- Estrogen and related hormone effects
- Inflammatory mediators and NSAID effects
- HER2/EGFR in Cancer Research
- Ocular Disorders and Treatments
- Corneal Surgery and Treatments
- Cytokine Signaling Pathways and Interactions
- Pharmacogenetics and Drug Metabolism
- Lung Cancer Research Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Metabolism and Genetic Disorders
- Vascular Anomalies and Treatments
- Childhood Cancer Survivors' Quality of Life
- Sesame and Sesamin Research
- Pharmacological Effects and Toxicity Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular Issues in Pregnancy
- Bone health and treatments
- Immunodeficiency and Autoimmune Disorders
- CAR-T cell therapy research
- Drug-Induced Adverse Reactions
- Plant Molecular Biology Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Cancer Treatment and Pharmacology
- Neurological and metabolic disorders
- Cancer therapeutics and mechanisms
Dalhousie University
2024
Western University
2016-2020
British Columbia Children's Hospital
2015-2017
University of British Columbia
2011-2017
Cisplatin-induced ototoxic effects are an important complication that affects testicular cancer survivors as a consequence of treatment. The identification genetic variants associated with this adverse drug reaction will further our mechanistic understanding its development and potentially lead to strategies prevent effects.To identify the cisplatin-induced in adult patients.This retrospective study was performed by Canadian Pharmacogenomics Network for Drug Safety using patients recruited...
BACKGROUND: Many treatment options are now available for patients with idiopathic pulmonary arterial hypertension (IPAH). Data regarding the optimal combination of therapies lacking, as is consensus on how to assess response therapy and when change therapeutic regimens. OBJECTIVES: To gather opinions Canadian (PH) experts standard practice in care IPAH after initiated. METHODS: PH physicians were surveyed using short questionnaires their practices patients. A Delphi forecasting approach was...
Non-hepatic causes of hyperammonaemia are uncommon relative to hepatic aetiologies. An adolescent female was admitted the hospital with a diagnosis very severe aplastic anaemia. During her treatment immunosuppressive therapy, she developed neutropenic enterocolitis, pseudomonal bacteraemia and hyperammonaemia. A combination intermittent haemodialysis high-volume continuous veno-venous haemodiafiltration (CVVHDF) required manage Despite thorough investigation, there were no hepatic, metabolic...