A5084711505- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Corneal Surgery and Treatments
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Infectious Aortic and Vascular Conditions
- Carbohydrate Chemistry and Synthesis
- Cardiovascular Health and Disease Prevention
- Viral Infections and Immunology Research
- Intracranial Aneurysms: Treatment and Complications
- Aerosol Filtration and Electrostatic Precipitation
- Acute Kidney Injury Research
- Extracellular vesicles in disease
- Infection Control and Ventilation
- RNA and protein synthesis mechanisms
- Cardiac Arrest and Resuscitation
- Photochromic and Fluorescence Chemistry
- Mesenchymal stem cell research
- Corneal surgery and disorders
- Prosthetics and Rehabilitation Robotics
- RNA Interference and Gene Delivery
- South Asian Cinema and Culture
- Pluripotent Stem Cells Research
- Musculoskeletal Disorders and Rehabilitation
- Cerebrovascular and Carotid Artery Diseases
Indiana University – Purdue University Indianapolis
2023-2024
University of Pennsylvania
2020-2022
University of Pittsburgh
2016-2020
National Institute for Occupational Safety and Health
2017
Pennsylvania State University
2016
Mesenchymal stem cells from corneal stromal (CSSC) prevent fibrotic scarring and stimulate regeneration of transparent tissue after wounding in mice. These effects rely on the ability CSSC to block neutrophil infiltration into damaged cornea. The current study investigated hypothesis that by is mediated secreted extracellular vesicles (EVs). produced EVs 130-150 nm diameter with surface proteins include CD63, CD81, CD9. reduced visual murine wounds as effectively did live cells, but human...
The HIV-1 envelope glycoprotein gp120 is heavily glycosylated and bears numerous high mannose sugars. These sugars can serve as targets for HIV-inactivating compounds, such antibodies lectins, which bind to the glycans interfere with viral entry into target cell. We determined 1.6 Å x-ray structure of Cyt-CVNH, a recently identified lectin from cyanobacterium Cyanothece(7424), elucidated its glycan specificity by NMR. Cyt-CVNH recognition profile are similar those other CVNH proteins, each...
Corneal stromal stem cells (CSSC) reduce corneal inflammation, prevent fibrotic scarring, and regenerate transparent tissue in injured corneas. These effects rely on factors produced by CSSC to block the gene expression. This study investigated mechanism of scar-free regeneration effect.Primary human (hCSSC) from donor rims were cultivated passage 3 co-cultured with mouse macrophage RAW264.7 induced M1 pro-inflammatory phenotype treatment interferon-γ lipopolysaccharides, or M2...
A 70-year-old woman with a bioprosthetic aortic valve replacement for endocarditis complicated by recurrent and requiring homograft root 10 years earlier had presented at 1 month after her admission pseudomonal bacteremia right-sided chest pain. An pseudoaneurysm, identified on computed tomography, was treated an ascending aorta thoracic endovascular repair using two overlapping abdominal stent grafts in the aorta. Postoperative follow-up imaging demonstrated exclusion of pseudoaneurysm...
Gun violence reached a 20-year peak in 2020, with the first-line treatment of axillosubclavian vascular injuries (SAVIs) remaining unknown. Traditional open exposure is difficult and exposes patients to iatrogenic venous brachial plexus injury. The practice endovascular has been increasing. We performed retrospective analysis SAVIs at level I trauma center. Seven were identified. Endovascular repair was five patients. Technical success 100%. early results suggest that trauma-related can be...
Abdominal aortic aneurysms (AAA) are diagnosed in over 200,000 patients per year the United States. Endovascular AAA repair offers a strategy for those unable to undergo open operation; however there still exists treatment gap whose anatomy is not suitable current stent graft options. In response this need novel therapeutics prevent aneurysm proliferation, objective of work was expand options via anti-inflammatory hydrogel application with handheld bioprinting device. Induction 8-week-old,...
This case describes a patient who underwent endovascular repair for an extent V thoracoabdominal aneurysm with planned coverage of the celiac artery. Following deployment stent graft, superior mesenteric artery was shuttered, and subsequently developed signs symptoms bowel ischemia. The successful retrograde open stenting resolution her symptoms. Although (ROMS) has been primarily shown to be effective in acute ischemia, this demonstrates that ROMS can used as salvage option shuttering...
J. Daniel Elam, Impossible and Necessary: Anticolonialism, Reading, Critique. Hyderabad: Orient Blackswan, 2021, 212 pp., ₹895, ISBN: 9788194925835