A5014559391- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Fetal and Pediatric Neurological Disorders
- Protist diversity and phylogeny
- Legume Nitrogen Fixing Symbiosis
- Microbial Community Ecology and Physiology
University of Freiburg
2022-2025
University Medical Center Freiburg
2025
University of Konstanz
2022
Hypothalamic hamartomas (HHs) are associated with pharmacoresistant epilepsy. Stereotactic radiofrequency thermocoagulation (SRT) shows promise as a disconnecting intervention. Although magnetic resonance imaging (MRI) is typically used to determine the attachment and intervention side, it presents challenges in cases of bilaterally attached HH, where epileptogenic side unclear. The lateralizing potential electroclinical parameters such remains uncertain. This retrospective study evaluates...
Abstract Objective What factors influence cognition and behavior in patients with epilepsy caused by hypothalamic hamartoma (HH)? Methods We conducted a retrospective study of 103 referred to the Epilepsy Center Freiburg, Germany, over past 24 years. Analyzed parameters included development/intellectual functioning, behavior, seizure types frequency, as well electroencephalography (EEG) magnetic resonance imaging (MRI) analyses. Results Half showed signs global developmental delay (GDD) or...
Abstract Endosymbiosis, an interaction between two species where one lives within the other, has evolved multiple times independently, but underlying mechanisms remain unclear. Evolutionary theory suggests that for endosymbiotic to stable over time, births of both partners should be higher than their deaths in symbiosis and when living independently. However, experimentally measuring this can difficult conclusions tend focus on host. Using a ciliate–algal system ( Paramecium bursaria host...