A5086311815- Bone health and osteoporosis research
- Bone health and treatments
- Electromagnetic Fields and Biological Effects
- Laser Applications in Dentistry and Medicine
- Bone Metabolism and Diseases
- Advanced Chemical Sensor Technologies
- Gas Sensing Nanomaterials and Sensors
- Pain Mechanisms and Treatments
- Spaceflight effects on biology
- Analytical Chemistry and Sensors
- Nerve injury and regeneration
- Infrared Thermography in Medicine
- Signaling Pathways in Disease
- Vitamin D Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cellular Mechanics and Interactions
- Genetic and Kidney Cyst Diseases
- Management of metastatic bone disease
- Connective Tissue Growth Factor Research
- Winter Sports Injuries and Performance
- Graphite, nuclear technology, radiation studies
- Orthopaedic implants and arthroplasty
- Cancer Treatment and Pharmacology
- Radiation Therapy and Dosimetry
- Thermoregulation and physiological responses
Air Force Medical University
2013-2025
Chongqing University of Technology
2021-2022
A large body of evidence indicates that pulsed electromagnetic fields (PEMF), as a safe and noninvasive method, could promote in vivo vitro osteogenesis. Thus far, the effects underlying mechanisms PEMF on disuse osteopenia and/or osteoporosis remain poorly understood. Herein, efficiency osteoporotic bone microarchitecture, strength, metabolism, together with its associated signaling pathway mechanism, was systematically investigated hindlimb-unloaded (HU) rats. Thirty young mature...
Growing evidence has demonstrated that pulsed electromagnetic field (PEMF), as an alternative noninvasive method, could promote remarkable in vivo and vitro osteogenesis. However, the exact mechanism of PEMF on osteopenia/osteoporosis is still poorly understood, which further limits extensive clinical application PEMF. In present study, efficiency osteoporotic bone microarchitecture quality together with its associated signaling pathway mechanisms was systematically investigated...
Abstract The hypobaric hypoxia environment found at high altitudes imposes various reversible and irreversible detrimental effects on living organisms. Accumulating evidence suggests that negatively impacts skeleton health by diminishing bone quality disrupting microarchitecture. However, therapeutic strategies to counteract this loss remain limited. This study investigates the impact of whole‐body vibration (WBV) stimulation skeletal rats continuously exposed simulated an altitude 4500 m...
Radiotherapy increases tumor cure and survival rates; however, radiotherapy-induced bone damage remains a common issue for which effective countermeasures are lacking, especially considering recurrence risks. We report high-specificity protection technique based on noninvasive electromagnetic field (EMF). A unique pulsed-burst EMF (PEMF) at 15 Hz 2 mT induces notable Ca2+ oscillations with robust spikes in osteoblasts contrast to other waveforms. This waveform parameter substantially...
Although numerous clinical studies have reported that pulsed electromagnetic fields (PEMF) a neuroprotective role in patients with diabetic peripheral neuropathy (DPN), the application of PEMF for clinic is still controversial. The present study was designed to investigate whether has therapeutic potential relieving neuropathic symptoms streptozotocin (STZ)-induced rats. Adult male Sprague–Dawley rats were randomly divided into three weight-matched groups (eight each group): non-diabetic...
The effects of load-induced interstitial fluid shear stress (FSS) on instantaneous signaling response osteocytes (e.g., calcium signaling) have been well documented. FSS can also initiate the release many important messenger molecules ATP and PGE2 ). However, cellular function bone metabolism-modulating cytokine expression not fully identified (some inconsistent/conflicting results documented). Herein, osteocyte-like MLO-Y4 cells were stimulated with 1 Pa, 2-h FSS, morphology, cytoskeletal...
Extremely low frequency pulsed magnetic fields (ELFPMF) have been shown to induce Faraday currents and measurable effects on biological systems. A kind of very high electromagnetic field was reported that it improved the symptoms diabetic nephropathy (DN) which is a major complication diabetes. However, few studies examined ELFPMF DN at present. The present study designed investigate in streptozotocin (STZ)-induced type 1 rats.Adult male SD rats were randomly divided into three...
Abundant evidence has substantiated the positive effects of pulsed electromagnetic fields (PEMF) and static magnetic (SMF) on inhibiting osteopenia promoting fracture healing. However, osteogenic potential rotating (RMF), another common application modality, remains poorly characterized thus far, although numerous commercial RMF treatment devices have been available market. Herein impacts osteoporotic bone microarchitecture, strength metabolism were systematically investigated in...
Gas sensor plays a key role in many applications with sensitivity being critical performance characteristic.Increasing the surface area of gas sensing material is one approach that can increase sensitivity.Fractal geometries, which have large specific and special fractal dimension, previously been successfully used design macro microstructures sensors to improve their performance.In this paper, influence geometrical structure substrate on has investigated.Two structures (Koch snowflake...
Although numerous clinical studies have reported that pulsed electromagnetic fields (PEMF) a neuroprotective role in patients with diabetic peripheral neuropathy (DPN), the application of PEMF for clinic is still controversial.The present study was designed to investigate whether has therapeutic potential relieving neuropathic symptoms streptozotocin (STZ)-induced rats.Adult male Sprague-Dawley rats were randomly divided into three weightmatched groups (eight each group): non-diabetic...
Following radiotherapy, patients have decreased bone mass and increased risk of fragility fractures. Diabetes mellitus (DM) is also reported to detrimental effects on architecture quality. However, no clinical or experimental study has systematically characterized the phenotype diabetic following radiotherapy. After one month streptozotocin injection, three-month-old male rats were subjected focal radiotherapy (8 Gy, twice, at days 1 3), then mass, microarchitecture, turnover as well cell...
With the development of society and diversification application requirements, new demands are being placed on performance gas sensors. Traditional research sensors has focused sensitive materials, including materials compounding existing materials. In this paper, we take an alternative approach to optimization electrode structure gas-sensitive by combining fractal geometry with sensor design. The is further enhanced large specific surface area strong electric field properties geometry....
The traditional parameters to evaluate human microcirculation such as mean values of skin blood flux (SBF) and velocity flow measured by laser Doppler flowmetry (LDF) failed find the biological effects magnetic field (MF) on according numerous researches.