- Marine Sponges and Natural Products
- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Microbial Metabolism and Applications
- Enzyme-mediated dye degradation
- Seaweed-derived Bioactive Compounds
- Bioactive Compounds and Antitumor Agents
- Synthesis of Indole Derivatives
- Microbial bioremediation and biosurfactants
- Microbial Community Ecology and Physiology
- Biochemical and biochemical processes
- Chromium effects and bioremediation
- Plant biochemistry and biosynthesis
- Heavy metals in environment
G.S. Science, Arts And Commerce College
2019-2021
National Institute of Oceanography
2016
Council for Scientific and Industrial Research
2013
Council of Scientific and Industrial Research
2008-2012
A deep-sea isolate of the psychrotolerant yeast Cryptococcus sp. (NIOCC#PY13) obtained from polymetallic nodule-bearing sediments Central Indian Basin was examined for its capacity to grow in presence various concentrations heavy metal salts i.e., ZnSO4 , CuSO4 Pb(CH3 COO)2 and CdCl2 . It demonstrated considerable growth 100 mg/l above-mentioned four both at 30°C 15°C. This strain tolerated comparatively higher levels these than other terrestrial isolates belonging Cryptococcus, Rhodotorula,...
Abstract The marine fungus, Aspergillus flavipes (MTCC 5220), was isolated from the pneumatophore of a mangrove plant Acanthus ilicifolius found in Goa, India. crude extract A. to show anti‐inflammatory activity. It blocked interleukin‐6 (IL‐6) and tumor necrosis factor‐ α (TNF‐ ) production lipopolysaccharide (LPS)‐activated THP‐1 cells with IC 50 2.69±0.5 μM 6.64±0.4 μM, respectively. chemical investigation led isolation optically inactive 4 β ‐[(1 E )‐propen‐1‐yl]cyclopentane‐1 ,2 ‐diol (...
Abstract Marine fungi Aspergillus flavipes and A. terreus were investigated for secondary metabolites using electrospray ionization‐quadrupole time‐of‐flight mass spectrometry (ESI‐QTOF MS) analysis. The ESI‐MS analysis showed that molecular ion peaks compounds, terrein (1) , butyrolactone I (2) I‐carboxylic acid (3) III (4) while, had additional presence of new compound aspernolide Q (5) with absence . By tandem data, the prominent fragment ions helped in establishing structure compounds...
Abstract: The indole nucleus is one of the most important ring systems for pharmaceutical development. Various natural products new molecular structures with diverse biological activities have been reported from marine flora and fauna, thus ensuring motivation in search newer products. unique structural features triindole containing three rings impressive make these alkaloids an attractive target drug discovery. This mini-review highlights significance various strategic innovations towards...