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The Journal of Orthopaedic Research, a publication the Research Society (ORS), is forum for rapid high quality reports new information on full spectrum orthopaedic research, including life sciences, engineering, translational, and clinical studies.

Abstract Large scale cortical allografts suffer from poor incorporation and healing often end in graft failure 5–10 years after implantation. To reduce these failures we have developed a growth‐factor loaded allograft capable of delivering one or two factors with degree temporal control precision that permits the early release growth factor followed by later more sustained other. We vascular endothelial (VEGF) bone morphogenetic protein‐2 (BMP‐2), both critical components formation repair,...

Background: This study compares the efficacy, safety, and resource utilization of brachial plexus + cutaneous nerve blocks (RAG) versus conventional anesthesia (CAG) in patients undergoing clavicle fracture surgeries. Methods: A total 100 were enrolled equally divided into RAG (n=50) CAG groups. Baseline characteristics, intraoperative postoperative outcomes, complications, length hospital stay, evaluated. Pain control was assessed using Visual Analog Scale (VAS), patient satisfaction...

Addison's disease presents a unique challenge when it occurs during pregnancy due to its potential for maternal and fetal complications if left untreated. This review synthesizes present information about the pathophysiology clinical aspects of using from case reports. Pregnancy-induced physiological changes can complicate diagnosis adrenal insufficiency as symptoms overlap with typical symptoms; high index suspicion is therefore necessary. Diagnostic tests include short synacthen...

Abstract According to 5‐ and 10‐year clinical follow‐up studies large‐scale bone allografts have a high failure rate, largely due poor allograft incorporation with adjacent subsequent remodeling. The goal of this study was develop methodology deliver growth factors from in temporally controlled manner. Intact long were coated micron‐scale thick layer degradable polymer that maintained inherent pore structures acted as delivery vehicle for morphogenetic protein‐2 vascular endothelial factor....

Summary Objectives To evaluate the clinical outcomes and costs of managing pneumonia severe malnutrition in a day clinic (DC) management model (outpatient) vs . hospital care (inpatient). Methods Randomised trial where children aged 2 months to 5 years with were randomly allocated DC or inpatient care. We used block randomisation variable length from 8 20 produced computer‐generated random numbers that assigned one two interventions. Successful was defined as resolution signs being...

Cervical cancer is the most common in Bangladesh, spite of having established screening program. This cross-sectional study was performedin Bangabandhu Sheikh Mujib Medical University (BSMMU) from July 2012- June2013 to determine attitude and practice cervical among 401 female doctors BSMMU. All information collected a structured questionnaire data were analyzed using SPSS version: 17.0. About 40.9% had good knowledge regarding 80.8percent did not ever have test. The less participants’ age,...

Objective: To determine the urinary tract infections (UTIs)-causing bacterial profile and antibiotic susceptibility pattern for proper complete treatment of UTIs in pregnant women with diabetes mellitus (DM). Methods: We collected 300 urine samples from diabetic nondiabetic at various gestational ages. After isolating identifying uropathogens, we conducted an sensitivity assay against fourteen commonly used antibiotics: amikacin, amoxicillin, ampicillin, azithromycin, cefixime, ceftazidime,...

Abstract Introduction The purpose of this study was to examine the safety and feasibility laparoscopically assisted vaginal hysterectomy for uteri weighing more than 500 g as compared less in benign gynecological diseases. Methods This a retrospective study. Patients were admitted through outpatient department. They divided into two groups: uterine weight ≥500 (group 1) >500 2). There no exclusion criteria based on size, number, or location leiomyomas. patient characteristics groups terms...

Background: Birth preparedness and complication readiness is an imperative intervention which has proven to reduce delays in care seeking behavior case of obstetric emergencies. Although, many pregnant women their families do not take the suggested steps prepare for childbirth, despite being known them. Additionally, marked disparities often have been observed between rural urban areas, with more maternal neonatal deaths occurring areas owing unpreparedness. This study thus set out assess...

Background: Cervical cancer is the second most common malignancy of women in Bangladesh. Surgery mainstay treatment patients with early invasive confined to cervix. While five-year survival rate after surgery for stage IB1 disease exceeds 90%, it only 60% - 70% IB2 and IIA2 (tumor size > 4 cm). To improve outcome treatment, two three cycles Neoadjuvant Chemotherapy (NACT) has been evaluated as a strategy diseases. Objectives: This study aimed evaluate role neoadjuvant chemotherapy followed...

Background: Cervical cancer develops from well-defined precursor lesions in a variable period of time. Detecting early or pre invasive stages, cervical is preventable and curable, so detection preinvasive very important. Objectives: The aim our study was to correlate Pap smear colposcopy relation histopathological findings lesion cervix. Methods: This cross-sectional 110 women attend department Gynecological Oncology OPD Bangabandhu Sheikh Mujib Medical University Hospital July 2016 June...

Klippel-Trenaunay syndrome (KTS) is not a common congenital vascular abnormality. A trio of capillary malformation, venous varicosities, and bony or soft-tissue hypertrophy define this syndrome. Significant morbidities associated with illness include bleeding, deep vein thrombosis, embolic consequences. Angiokeratoma circumscriptum naeviforme (ACN) indeed variant angiokeratoma that appears as hyperkeratotic plaque on the lower extremity. Bilateral anorchia (BCA) total lack testicular tissue...

Background: Emergency Department is very important place for the patient. Objective: The purpose of present study was to assess trend patients attended at emergency department referral neurosciences hospital in Bangladesh. Methodology: This a retrospective carried out from January 2018 2021. Microbiology National Institute Neurosciences & Hospital, Dhaka, Dhaka has been started its journey September, 2012. It situated health hub Sher-E-Bangla Nagar, only Govt. run tertiary care...

Fibrocalculous pancreatic diabetes (FCPD) is atypical but unique variety of diabetes, in which chronic inflammation and calcification lead to exocrine endocrine failure the pancreas, primarily occurs tropical countries. At an early age, these diabetic children are at risk developing disabling life-threatening complications, putting a major human economic burden on families societies. Here, authors report case young female patient presenting with clinical features FCPD. BANGLADESH J CHILD...

Introduction: Children with cerebral palsy (CP) in Bangladesh suffer immensely, no means or hope for a decent life and public system lacking basic facilities.This study aims to analyze the quality of (QoL) depression status parents among children CP, as well relationship between these factors their demographic profile. Materials Methods: This is descriptive cross-sectional which data were collected from Pediatric Department Centre Rehabilitation Paralysed (CRP) Savar. The participants...

Background: Polytrauma is a public health problem in every country. Objective: The purpose of the present study was to assess incidence Casualty Emergency Department tertiary care hospital Dhaka city. Methodology: This cross-sectional carried out casualty Medical College Hospital, Dhaka, Bangladesh. patients who were admitted from January 2014 December included this study. includes all with polytrauma, most whom underwent laparotomy or other types surgery like suprapubic cystostomy,...