Nicole Hwajin Park

ORCID: 0000-0001-8311-8538
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About
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Research Areas
  • Metabolism, Diabetes, and Cancer
  • Cancer, Hypoxia, and Metabolism
  • Diet and metabolism studies
  • Liver Disease Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Diet, Metabolism, and Disease
  • Genomics, phytochemicals, and oxidative stress

University of Illinois Urbana-Champaign
2021-2023

Abstract Estrogen receptor–positive (ER+) metastatic tumors contribute to nearly 70% of breast cancer–related deaths. Most patients with ER+ cancer (MBC) undergo treatment the estrogen receptor antagonist fulvestrant as standard care. Yet, among such patients, metastasis in liver is associated reduced overall survival compared other sites. The factors underlying responsiveness metastases ER-targeting agents remain unknown, impeding development more effective approaches improve outcomes for...

10.1158/1541-7786.mcr-21-0781 article EN Molecular Cancer Research 2022-03-08

Abstract Estrogen receptor-positive (ER + ) metastatic tumors contribute to nearly 70% of breast cancer-related deaths. Most patients with ER cancer (MBC) undergo treatment the estrogen receptor antagonist fulvestrant (Fulv) as standard-of-care. Yet, among such patients, metastasis in liver is associated reduced overall survival compared other sites. The factors underlying responsiveness metastases ER-targeting agents remain unknown, impeding development more effective approaches improve...

10.1101/2021.09.07.458711 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2021-09-07

<div>Abstract<p>Estrogen receptor–positive (ER<sup>+</sup>) metastatic tumors contribute to nearly 70% of breast cancer–related deaths. Most patients with ER<sup>+</sup> cancer (MBC) undergo treatment the estrogen receptor antagonist fulvestrant as standard care. Yet, among such patients, metastasis in liver is associated reduced overall survival compared other sites. The factors underlying responsiveness metastases ER-targeting agents remain unknown,...

10.1158/1541-7786.c.6545651.v1 preprint EN 2023-04-03

<div>Abstract<p>Estrogen receptor–positive (ER<sup>+</sup>) metastatic tumors contribute to nearly 70% of breast cancer–related deaths. Most patients with ER<sup>+</sup> cancer (MBC) undergo treatment the estrogen receptor antagonist fulvestrant as standard care. Yet, among such patients, metastasis in liver is associated reduced overall survival compared other sites. The factors underlying responsiveness metastases ER-targeting agents remain unknown,...

10.1158/1541-7786.c.6545651 preprint EN 2023-04-03
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