A5075165121- Systemic Lupus Erythematosus Research
- Spondyloarthritis Studies and Treatments
- Renal Diseases and Glomerulopathies
- Rheumatoid Arthritis Research and Therapies
- Assisted Reproductive Technology and Twin Pregnancy
- Bone and Joint Diseases
- Oral health in cancer treatment
- Atherosclerosis and Cardiovascular Diseases
- Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Vasculitis and related conditions
- Psoriasis: Treatment and Pathogenesis
- Immunodeficiency and Autoimmune Disorders
- Hormonal and reproductive studies
- Blood Coagulation and Thrombosis Mechanisms
- Pediatric Urology and Nephrology Studies
- Birth, Development, and Health
- Osteomyelitis and Bone Disorders Research
- Bone health and osteoporosis research
- Sperm and Testicular Function
- Liver Disease Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Sexual Differentiation and Disorders
- Platelet Disorders and Treatments
The University of Western Australia
2018-2022
Curtin University
2021
Objective. To compare the long-term prevalence, incidence, and outcomes of vertebral fracture (VF) between ankylosing spondylitis (AS) patients matched controls, including role extraarticular manifestations (EAM) osteoporosis. Methods. This was a statewide observational study using linked health data for 2321 with AS 22,976 controls presenting to hospital from 1980 2015. Data were analyzed incidence rates (per 1000 person-yrs) ratios (IRR), multivariable Cox proportional hazards regression,...
Objective. To examine mortality rates in hospitalized patients with ankylosing spondylitis (AS) and the association of extraarticular manifestations (EAMs) comorbidities rates. Methods. This study was a retrospective, population-based cohort using linked administrative data from AS who were (n = 1791) matched comparison group 8955). Mortality for obtained Western Australia Death Register. The presence EAMs identified hospital records. compared between 2 groups Cox proportional hazard models...
Objectives To investigate the current demographic, clinical and histological characteristics of patients with lupus nephritis (LN) in Western Australia (WA) regards to their predictive value for patient renal outcome. Methods Retrospective study adult systemic erythematosus (SLE) a first biopsy demonstrating LN between 1997 2017 at metropolitan tertiary hospital WA. Clinical data were collected baseline last follow-up findings classified by International Society Nephrology (ISN) criteria....
<h3>Background</h3> In Ankylosing Spondylitis (AS) chronic spinal inflammation contributes to osteoporosis and rigidity. Large scale studies on vertebral fractures in AS patients are scarce with rates reported between 0.4% 32%<sup>1–3</sup>. While biological therapy for has been associated better clinical outcomes, the long-term effect remains uncertain. <h3>Objectives</h3> To longitudinally investigate population wide fracture compare risk, disease burden survival age/gender matched...
Background: Systemic Lupus Erythematosus (SLE) is a chronic multiorgan disease with an unpredictable course, which requires monitoring for activity, treatment efficacy and comorbidity. Data on the healthcare utilization cost of SLE, especially from Australia are scarce. Objectives: To determine utilisation estimated costs inpatient admissions (IP), emergency (ED) outpatient (OPD) hospital visits investigations SLE patients in Western (WA). Methods: This longitudinal cohort study seen at...
Background: There is sparse population-level data on outcome in patients with Immunoglobulin-A vasculitis (IgAV) and none from Australia Objectives: We compared long-term mortality for paediatric adult IgAV age- gender-matched controls. Methods: Linked health pediatric (<20 years=473) (20+ years, n=267) were obtained state-wide hospital deaths registries Western the period 1980-2015. All-cause rates (MR) (deaths/1000 person-years) controls using rate ratios (MRR) general population of by...
Background/ObjectivePatients with IgA vasculitis (IgAV aka Henoch Schonlein) may require aggressive initial treatment, are prone to disease relapses and have sustained abnormal responsiveness. We investigated whether the relatively rare diagnosis of childhood IgAV is associated subsequent comorbidity, hospitalisation interventions.
 MethodsUsing linked administrative health data from Western Australian Rheumatic Disease Registry we performed an observational cohort study comparing ED...
Abstract Background Establishing causal effects in reproductive and perinatal epidemiology is challenging due to the many selection attrition processes from preconception postnatal period. Further challenging, potential for misclassification of exposures, outcomes confounders, contributing measurement error. The application simulation enables illustration quantification magnitude various types bias commonly found observational studies. Methods A systematic search was conducted PubMed,...