A5103258920- Nanoparticle-Based Drug Delivery
- Advanced Polymer Synthesis and Characterization
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Surfactants and Colloidal Systems
- Gas Sensing Nanomaterials and Sensors
- Dendrimers and Hyperbranched Polymers
- Luminescence and Fluorescent Materials
- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Lipid Membrane Structure and Behavior
- Electrospun Nanofibers in Biomedical Applications
- Hydrogels: synthesis, properties, applications
- Nanoplatforms for cancer theranostics
- Advanced ceramic materials synthesis
- Block Copolymer Self-Assembly
- Ionic liquids properties and applications
- Orthopaedic implants and arthroplasty
- Advanced Drug Delivery Systems
- Characterization and Applications of Magnetic Nanoparticles
- Analytical Chemistry and Sensors
- Advanced Chemical Sensor Technologies
- Advanced materials and composites
- Tissue Engineering and Regenerative Medicine
- Molecular Sensors and Ion Detection
University of Central Florida
2024-2025
University of Arizona
2024
Pusan National University
2021-2023
Indian Institute of Technology Kharagpur
2014-2018
Abstract With the advancement of medical and digital technologies, smart skin adhesive patches have emerged as a key player for complex purposes. In particular, with integrated electronics created an excellent platform monitoring health conditions intelligent medication. However, efficient design is still challenging it requires strong combination network structure, adhesion, physical properties, biocompatibility. To assimilated device, one must deep knowledge various patches. This article...
Success of chemotherapy as a treatment for cancer has been often inhibited by multidrug resistance (MDR) the cells. There is clear need to generate strategies overcome this resistance. In work, we have developed redox-responsive and core-cross-linked micellar nanocarriers using poly(ethylene glycol)-block-poly(2-(methacryloyloxy)ethyl 5-(1,2-dithiolan-3-yl)pentanoate) diblock copolymers (PEG-b-PLAHEMA) with tunable swelling properties delivery drugs toward drug-sensitive MDA-MB-231...
Materials used in aircraft engines, gas turbines, nuclear reactors, re-entry vehicles, and hypersonic structures are subject to severe environmental conditions that present significant challenges. With their remarkable properties, such as high melting temperatures, strong resistance oxidation, corrosion, ablation, minimal creep, advantageous thermal cycling behavior, ceramic matrix composites (CMCs) show great promise a material meet the strict requirements these kinds of environments....
The ability to regulate the formation of nanostructures through self-assembly amphiphilic block copolymers is immense significance in field biology and medicine. In this work, a new copolymer synthesized by using reversible addition-fragmentation chain transfer (RAFT) polymerization technique from poly(ethylene glycol) monomethyl ether acrylate (PEGMA) Boc-l-tryptophan acryloyloxyethyl ester (Boc-l-trp-HEA) was found spontaneously form pH-responsive water-soluble after removal Boc group....
The motion of organs and tissues causes X-ray localization error during radiation therapy. Physical phantoms utilizing materials with tissue-equivalent mechanical radiological properties are therefore desired to simulate organ for radiotherapy optimization. However, the development such is still a challenge. Alginate hydrogel has similar extra cellular matrix, which make it promising use as material. In this study, alginate foams were synthesized by in-situ release Ca2+. air volume ratio was...
In this article, we have reported the synthesis and physicochemical characterization of a novel l-glycine amino acid derived cholesterol based surface active ionic liquid (SAIL). This SAIL has been explored for preparation (IL)-in-oil microemulsions vesicles. The formation IL-in-oil microemulsion is characterized by construction ternary phase diagram, dynamic light scattering (DLS) measurement, proton nuclear magnetic resonance (1H NMR) study, fluorescence measurement using coumarin 480...
Formation and disintegration of self-assembled nanostructures in response to external stimuli are important phenomena that have been widely explored for a variety biomedical applications. In this contribution, we report the thermally triggered assembly block copolymer molecules aqueous solution form vesicles (polymersomes) their disassembly on reduction temperature. A new thermoresponsive diblock poly(N-isopropylacrylamide) poly((3-methacrylamidopropyl)trimethylammonium chloride)...
Interaction studies between a set of poly(ethylene glycol) (PEG) based cationic bottle-brush block copolymers (BBCPs) and calf thymus DNA (ctDNA) were carried out using steady state fluorescence spectroscopy, UV melting experiments dynamic light scattering measurements. Results suggested that these could effectively bind with negatively charged DNA. Although electrostatic interaction is believed to be the predominant contributing factor in overall binding process, hydrophobic interactions...
Doxorubicin release at preferred lysosomal pH of the cancer cells due to pH-induced de-crosslinking polymer nanoparticle core.
Development of water-soluble chemosensors that are selective and sensitive to Cu2+ ions is tremendous importance owing their potential applications in biological systems. In the present work, we report synthesis a new polymer containing pendant rhodamine units capable highly detection aqueous medium. Poly(2-pyrrolidinemethyl acrylate) was prepared using RAFT polymerization technique. The pyrrolidine nitrogen group subjected Aza-Michael type addition with ethyl acrylate followed by covalent...
We describe the development of a polymeric vesicle that not only selectively fluoresces at low pH, condition prevailing in cancer cells, but also can potentially monitor thermoresponsive release drug even if is nonfluorescent. The developed fluorescence resonance energy transfer (FRET)-based vesicular nanocarriers are composed new poly(PEGMA)-b-poly(NIPA-r-R6GMED) block copolymer, which undergoes pH-switchable superior turn on-off characteristics. copolymer was synthesized using RAFT...
Alginate hydrogels possess properties analogous to those of the extracellular matrix (ECM). Thus, their mechanical behavior approximates soft tissue, which makes them desirable for production tissue-equivalent deformable structures. This study aims determine synthesis-structure-property relationship alginate hydrogel with Young's modulus in range 10°~101 kPa, mimicking that human lung tissue. Hydrogels, a 3D polymer network embedded water-rich environment. Homogeneous are synthesized by...
The current work outlines the finding of a distinctive method to detect hazardous fluoride ions in water below permissible limits using waste material-based self-healable triboelectric nanogenerator. In this work, authors showed steps involved chemisorption-based self-powered sensor. device is made-up materials like BSR rubber, used polythene bags, and plastic sheets, which validates energy conversion ability with maximum output voltage ~242 volts 40 μA current. present detection displays...
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