A5101676030- Immunotherapy and Immune Responses
- Toxin Mechanisms and Immunotoxins
- Caveolin-1 and cellular processes
- Energy and Environment Impacts
- Advanced Vision and Imaging
- CAR-T cell therapy research
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Traditional Chinese Medicine Analysis
- Computer Graphics and Visualization Techniques
- Cancer Immunotherapy and Biomarkers
- Neuroinflammation and Neurodegeneration Mechanisms
- Anesthesia and Neurotoxicity Research
- Mitochondrial Function and Pathology
- RNA Interference and Gene Delivery
- Neuroscience and Neuropharmacology Research
- Image Enhancement Techniques
- Vitamin C and Antioxidants Research
Fudan University
2025
Zhongshan Hospital
2025
Tongji University
2021-2024
Shanghai Tenth People's Hospital
2024
Wenzhou Medical University
2020
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2020
Obesity, a surging global health challenge, necessitates effective, accessible and innovative therapeutic models. Here we develop spatiotemporally controllable microneedle (MN) drug delivery platform for sono-gene therapy to fight obesity. The delivers the methoxy polyethylene glycol-polyethyleneimine (mPEG-PEI) modified metal-organic frameworks (MOFs) sonosensitizer clustered regularly interspaced short palindromic repeats-activating (CRISPRa)/CRISPRa-uncoupling protein 1 (UCP1) system...
Changes in aerosol composition and its proportions can cause changes atmospheric visibility. Vision systems deployed outdoors must take into account the negative effects brought by visibility impairment. In order to develop vision algorithms that adapt low conditions, a large-scale dataset containing pairs of clear images their visibility-impaired versions (along with other annotations if necessary) is usually indispensable. However, it almost impossible collect large amounts such image real...
Abstract The therapeutic efficacy of vaccines for treating cancers in clinics remains limited. Here, a rationally designed cancer vaccine by placing immunogenically differential and clinically approved aluminum (Al) or manganese (Mn) 2D nanosheet (NS) architecture together with antigens is reported. Structurally optimal NS high molar ratio Mn to Al (MANS‐H) features distinctive immune modulation, markedly promoting the influx heterogeneous innate cells at injection site. Stimulation multiple...