A5030126800- Obstructive Sleep Apnea Research
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- MicroRNA in disease regulation
- Head and Neck Cancer Studies
- Voice and Speech Disorders
- RNA and protein synthesis mechanisms
- Circular RNAs in diseases
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- RNA Research and Splicing
- Cancer Mechanisms and Therapy
People's Hospital of Xinjiang Uygur Autonomous Region
2015-2024
Xinjiang Medical University
2015
Even through narrowing of the upper-airway plays an important role in generation obstructive sleep apnea (OSA), peripheral airways is implicated pre-obese and obese OSA patients, as a result decreased lung volume increased elastic recoil pressure, which, turn, may aggravate collapsibility. A total 263 male (n = 193) female 70) subjects who were to various degrees without history diseases expiratory flow limitation, but troubled with snoring or suspicion included this cross-sectional study....
MicroRNA (miRNA/miR) has been identified to be a promising tool in treating pharyngolaryngeal cancer. The present study aimed investigate the role of miR‑490‑5p regulation proliferation, migration, invasion and epithelial‑mesenchymal transition (EMT) cancer cells. data expression levels 45 cases were obtained from People's Hospital Xinjiang Uygur Autonomous Region, prediction target was conducted by bioinformatics verified using luciferase assay. Cell viability determined cell counting...
Inability to maintain upper-airway patency during sleep is a cause of obstructive apnea (OSA) and its sequelae. The associated syndrome (OSAS) common in obese populations, currently, nocturnal polysomnography the gold standard for diagnosing this conditions, but diagnostic procedures are expensive time-consuming. Therefore, identification new markers OSAS would be useful. This study aims examine receiver operating characteristics impulse oscillometry (IOS) parameters prediction preobese...
Study finds that eukaryotic translation initiation factor 3 subunit D (EIF3D) may play an important role in aberrant alternative splicing (AS) events tumors. AS possesses a pivotal both tumour progression and the constitution of microenvironment (TME). Regrettably, our current understanding remains circumscribed especially context immunogene-related (IGAS) profiles within Head Neck Squamous Cell Carcinoma (HNSC). In this study, we comprehensively analyzed function mechanism action EIF3D by...
Papillary thyroid microcarcinoma (PTMC) is a specific subgroup of papillary carcinoma and defined with the dimension ≤1 cm by WHO. Although it shows relatively high 10-year livability, metastasis PTMC into other tissues organs seriously affects daily life patients mortality. Therefore, genetic basis for needs to be explored effective therapeutic targets. Here, we conducted series comparative analysis transcriptional expression profile between without lymph node metastasis.Gene gene function...
Objective To appraise the respiratory mechanical properties, gastroesophageal acid reflux and serum pulmonary surfactant protein levels(SPSPL)in snorer, possible cause to change in properties of were aims discuss through appraised correlationship between those factors. Methods Consecutive snorer underwent polysomnography determine whether presence OSAS or not; Meanwhile, was measured by using impulse oscillometry, multichannel intraluminal impedance-pH monitoring use record 24 h...
Objective To explore the possible mechanism of gastroesophageal reflux in patients with obstructive sleep apnea hypopnea syndrome(OSAHS), this study evaluated correlation between mechanical characteristics therespiratory system and degree OSAHS. Methods From February 2014 to 2016, suspected OSAHS admitted hospital for first timein People′s Hospital Xinjiang Uygur Autonomous Region, were performed routine pulmonary function testand polysomnography(PSG), pulse oscillation system(IOS),...