A5023565303- Malaria Research and Control
- Toxoplasma gondii Research Studies
- interferon and immune responses
- Neurobiology and Insect Physiology Research
- Mosquito-borne diseases and control
- Bacteriophages and microbial interactions
- Lipid Membrane Structure and Behavior
- Invertebrate Immune Response Mechanisms
- Cytomegalovirus and herpesvirus research
Ludwig-Maximilians-Universität München
2021-2022
Abstract During transmission of malaria‐causing parasites from mosquitoes to mammals, Plasmodium sporozoites migrate rapidly in the skin search for a blood vessel. The high migratory speed and narrow passages taken by suggest considerable strain on maintain their shape. Here, we show that membrane‐associated protein, concavin, is important maintenance sporozoite shape inside salivary glands during migration skin. Concavin‐GFP localizes at cytoplasmic periphery concavin( − ) progressively...
Abstract Apicomplexan parasites, such as Toxoplasma gondii , possess unique organelles, cytoskeletal structures, signalling cascades, replicate by internal budding within a specialised compartment and actively invade exit the host cell, to name few aspects of biology that characterise this phylum. Due their huge phylogenetic distance from well established model organisms, opisthokonts, comparative genomics has limited capacity infer gene functions conserved proteins can fulfil different...
ABSTRACT During transmission of malaria-causing parasites from mosquitoes to mammals, Plasmodium sporozoites migrate rapidly in the skin search for a blood vessel. The high migratory speed and narrow passages taken by suggest considerable strain on maintain their shape. Here we report newly identified protein, concavin, that is important maintenance sporozoite shape inside salivary glands during migration skin. Concavin-GFP localized at cytoplasmic periphery concavin(−) progressively rounded...