A5084966071- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- COVID-19 Clinical Research Studies
- Vasculitis and related conditions
- Renal Diseases and Glomerulopathies
- Biosimilars and Bioanalytical Methods
- Sarcoidosis and Beryllium Toxicity Research
- Long-Term Effects of COVID-19
- Chronic Kidney Disease and Diabetes
- IgG4-Related and Inflammatory Diseases
- Systemic Sclerosis and Related Diseases
- Autoimmune and Inflammatory Disorders Research
- Dermatological and COVID-19 studies
- Acute Lymphoblastic Leukemia research
- Salivary Gland Disorders and Functions
- Diabetes and associated disorders
- Liver Disease Diagnosis and Treatment
- Urticaria and Related Conditions
- Renal Transplantation Outcomes and Treatments
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Eosinophilic Disorders and Syndromes
- Cystic Fibrosis Research Advances
- Diet, Metabolism, and Disease
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Mexican Social Security Institute
2013-2024
El Colegio de México
2023
Autonomous University of San Luis Potosí
2006-2022
Hospital Central Dr. Ignacio Morones Prieto
2013-2022
Hospital General De Zona
2013-2022
Center for Rheumatology
2022
Faculty (United Kingdom)
2022
Hospital General de Granollers
2021
Universidad Veracruzana
2019-2020
Hospital Comarcal de Inca
2018
Objective While COVID-19 vaccination prevents severe infections, poor immunogenicity in immunocompromised people threatens vaccine effectiveness. We analysed the clinical characteristics of patients with rheumatic disease who developed breakthrough after against SARS-CoV-2. Methods included partially or fully vaccinated SARS-CoV-2 between 5 January and 30 September 2021 were reported to Global Rheumatology Alliance registry. Breakthrough infections defined as occurring ≥14 days completion...
The objective of this study was the evaluation clinical, demographic and treatment-associated mortality factors in patients with diffuse alveolar haemorrhage (DAH) associated systemic lupus erythematosus (SLE). Clinical, laboratory test, SLEDAI-2K, predictors (APACHE II) different treatments including cyclophosphamide, methylprednisolone rituximab were evaluated SLE who diagnosed DAH, to determine potential association mortality. Twenty-nine episodes DAH 22 included (one patient four...
To evaluate factors associated with mortality and infections in patients systemic lupus erythematosus (SLE) diffuse alveolar hemorrhage (DAH).A retrospective chart review was carried out for medical admissions of a diagnosis SLE DAH 9 hospitals. Clinical laboratory data were recorded each patient at diagnosis.We included 57 episodes 50 (7 recurrences), 49 women (86%), 14 juvenile (24.6%); 24 had died (42.1%). In the we detected infection 22 (38.6%): 8 invasive fungal infections, 16 bacterial...
<h3>Background</h3> Posterior reversible encephalopathy syndrome (PRES) is a well-known but rare complication in patients (<1%) with systemic lupus erythematosus (SLE). However, current epidemiological data are quite scant. The aim of the present study was to describe potentially unrecognised risk factors. <h3>Patients and methods</h3> We performed multicentre, retrospective case–control Mexico between 1999 2014. included total 168 who accounted for 77 episodes PRES, as follows: SLE/PRES,...
Invasive fungal infections (IFI) are catastrophic diseases associated with a high mortality. Relatively few cases of IFI have been described in systemic lupus erythematosus (SLE) and their related factors not completely explored. We evaluated patients SLE.All both SLE admitted to our hospital the last 7 years were each was compared 5 hospitalized (controls). Demographic factors, duration SLE, treatment previous month compared.Sixty (10 50 controls). Median age 29 years. High C-reactive...
Objectives The objective of this paper was to evaluate correlations between kidney biopsy indexes (activity and chronicity) urinary sediment findings; the secondary find which components can discriminate proliferative from other classes lupus nephritis. Methods Lupus nephritis patients scheduled for a were included in our study. morning before biopsy, we took urine samples each patient. Receiver operating characteristic (ROC) curves plotted determine area under curve (AUC) test detecting...
To demonstrate the use of surface-enhanced Raman spectroscopy (SERS) to determine sialic acid (SA) levels in saliva using silver nanoparticles as substrates, adnexal mass patients scheduled for surgical intervention remove invasive masses, with aim compare SA benign tumor vs ovarian cancer patients.Quantification was accomplished by measuring their SERS and calibrating analytical reagent SA. The mean concentration from 37 resulted smaller (5.1 mg/dL) than 15 Ovarium (23 mg/dL). condition...
Diffuse alveolar haemorrhage (DAH) is an uncommon complication of systemic lupus erythematosus (SLE), and recurrences DAH with remission periods are unusual. We describe a young woman cachexia as the initial manifestation SLE who presented posterior reversible encephalopathy syndrome (PRES), intestinal vasculitis four episodes even though she was receiving combined immune suppressive therapy. After treatment rituximab (RTX) patient has not further DAH.
Objective. The aim of this study was to describe the prevalence erectile dysfunction (ED), as well associated demographic and clinical features, in men with systemic lupus erythematosus (SLE), by means a systematic, standardized evaluation. Methods. We performed transversal 8 tertiary care centers Latin America. included male patients ≥ 16 years who fulfilled 4 American College Rheumatology criteria for SLE had regular sexual activity, evaluated them International Index Erectile Function-5...
Objective Approximately one third of individuals worldwide have not received a COVID‐19 vaccine. Although studies investigated risk factors linked to severe among unvaccinated people with rheumatic diseases (RDs), we know less about whether these changed as the pandemic progressed. We aimed identify associated in different epochs corresponding major variants concern. Methods Patients RDs and were entered into Global Rheumatology Alliance Registry between March 2020 June 2022. An ordinal...
Healthy Wistar rats were supplemented during 20 weeks with commercial inulin (I) and Agave tequilana fructans (CAT), experimental from A. (EAT) salmiana (AS) mature stems, rice starch 10% (RS), standard feed for rodents (C). Feed intake was kept steady, but I, body weight abdominal adipose tissue (6.01 g) decreased at the end. Glucose (mg/dL) (C, 120.52; 110.69; CAT, 105.75; EAT, 115.48; AS, 101.63; RS, 121.82), total cholesterol 89.89; 64.48; 68.04; 68.74; 82), triglycerides 84.03; 59.52;...
Background Mycophenolic acid (MPA) is an effective oral immunosuppressive drug used to treat lupus nephritis (LN), which exhibits large pharmacokinetic variability. This study aimed characterize MPA behaviour in Mexican LN patients and develop a population model identified factors that influence Methods Blood samples from treated with mycophenolate mofetil (MMF) were collected pre dose up six hours post dose. concentrations determined by validated ultra-performance liquid chromatography...