A5082582910- Coordination Chemistry and Organometallics
- Catalytic Cross-Coupling Reactions
- Advanced Battery Materials and Technologies
- Electrochemical Analysis and Applications
- Inorganic and Organometallic Chemistry
- Fuel Cells and Related Materials
- Chemical Synthesis and Analysis
- Advanced NMR Techniques and Applications
- Catalytic C–H Functionalization Methods
- Asymmetric Hydrogenation and Catalysis
- Advanced Synthetic Organic Chemistry
- Synthesis and pharmacology of benzodiazepine derivatives
- NMR spectroscopy and applications
- Advancements in Battery Materials
- Radical Photochemical Reactions
- Chemical Reaction Mechanisms
- Analytical Chemistry and Chromatography
- Asymmetric Synthesis and Catalysis
- Electrocatalysts for Energy Conversion
- Innovative Microfluidic and Catalytic Techniques Innovation
Texas A&M University
2022-2025
Mitchell Institute
2022-2025
Herein, we describe a general and selective deprotonation functionalization reaction of tetrahydroquinolines at the 4–position using organolithiums phosphoramide ligands. In addition to development direct alkylation with primary secondary alkyl halides, Negishi cross–coupling protocol was realized afford products range aromatic halides. These methods were applied late‐stage installation into variety substrates including pharmaceuticals as well natural product analogues. The use thorough...
A gas rapid injection nuclear magnetic resonance (GRI-NMR) system has been constructed to investigate reactions requiring the use of reagents. The allows for accurate delivery gases under inert conditions a standard NMR glass tube inside spectrometer permitting in situ reaction monitoring be conducted which mimics performed at bench. provides unique avenue systems that require continuous and/or precise To showcase our newly GRI-NMR system, carbon dioxide binding with phosphine ligated nickel...
A long-standing problem in the area of organolithium chemistry has been need for a highly reactive Li-metal source that mimics Li-powders but advantage being freshly prepared from inexpensive and readily available Li-sources. Here, we report simple convenient activation method using liquid ammonia furnishes new form crystalline Li-dendrites. The Li-dendrites were shown to have ca. 100 times greater surface than conventional Li-sources created by prototypical mechanical methods. Concomitant...
We describe herein the design and synthesis of a new class dialkylarylphosphine ligands incorporating Lewis-basic urea subunit. The ligand consisted six linear steps was enabled by discovery N-to-N alkyl migration reaction. This series were applied in common palladium-catalyzed cross-coupling reactions for formation carbon-carbon carbon-nitrogen bonds moderate to high yields.
Herein, we describe a general and selective deprotonation functionalization reaction of tetrahydroquinolines at the 4–position using organolithiums phosphoramide ligands. In addition to development direct alkylation with primary secondary alkyl halides, Negishi cross–coupling protocol was realized afford products range aromatic halides. These methods were applied late-stage installation into variety substrates including pharmaceuticals as well natural product analogues. The use thorough...
A long-standing problem in the area of organolithium chemistry has been need for a highly reactive Li–metal source that mimics Li–powders but advantage being freshly prepared from inexpensive and readily available Li–sources. Here we report simple convenient activation method using liquid ammonia furnishes new form crystalline Li–dendrites. The Li–dendrites were shown to have ca 100 times greater surface than conventional Li–sources created by prototypical mechanical methods. Concomitant...
Oxygen reduction reaction (ORR) electrocatalysts that provide high activity, long-term stability, and reduced precious metal content are needed for proton-exchange membrane fuel cells (PEMFCs). Typically, carbon is used as a catalyst support; however at elevated voltages encountered during start-up/shut-down, corrosion occurs which can significantly reduce the stability of catalyst. Tantalum pentoxide (Ta 2 O 5 ) stable under oxidative potentials acidic conditions oxygen reaction, but prior...