Constanza Alanis

ORCID: 0000-0001-8767-6887
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About
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Research Areas
  • Endometriosis Research and Treatment
  • Cytokine Signaling Pathways and Interactions
  • Birth, Development, and Health
  • Neuroendocrine regulation and behavior
  • Effects and risks of endocrine disrupting chemicals
  • Reproductive System and Pregnancy
  • Hypothalamic control of reproductive hormones

University of Chile
2022-2024

Leukaemia inhibitory factor (LIF) is a cytokine belonging to the interleukin-6 family that important at reproductive level in uterine implantation process. However, there very little evidence regarding its effect ovarian level. The aim of this work was study local involvement LIF/LIFRβ system follicular development and steroidogenesis rat ovaries. To carry out research, LIF/LIFR/GP130 transcript protein levels were measured fertile sub-fertile ovaries, vitro experiments performed assess...

10.1530/joe-22-0255 article EN Journal of Endocrinology 2023-04-20

Increased norepinephrine (NE) release from the sympathetic nerves during pregnancy in women or animal models, as occurs stress, modifies fetal environment and increases flow of NE to fetus, programing progeny affecting its cardiovascular metabolic function adulthood. In present work, gestating rats were exposed stress gestation female was analyzed for heart function. Pregnant Sprague–Dawley cold (4 °C/3 h/day); rats’ euthanized at 4, 20 60 days old their hearts...

10.20944/preprints202406.1234.v1 preprint EN 2024-06-19
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