A5101975173- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroendocrine Tumor Research Advances
- Cancer Immunotherapy and Biomarkers
- Ionosphere and magnetosphere dynamics
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Respiratory Support and Mechanisms
- Cancer therapeutics and mechanisms
- Quantum, superfluid, helium dynamics
- Earthquake Detection and Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Peptidase Inhibition and Analysis
- Solar and Space Plasma Dynamics
- PI3K/AKT/mTOR signaling in cancer
- Superconducting Materials and Applications
- Cancer Treatment and Pharmacology
- Metastasis and carcinoma case studies
- Neonatal Health and Biochemistry
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metal complexes synthesis and properties
- Pancreatic and Hepatic Oncology Research
Kitasato University
2014-2024
Oita University Hospital
2024
Nihon University
2021
Hyogo Medical University
2021
Riau University
2019
Fukujuji Hospital
2019
Grantham Hospital
2019
Far Eastern Scientific Centre of Physiology and Pathology of Respiration Russian Academy of Medical Sciences
2019
National Institute of Information and Communications Technology
2004-2017
Osaka City General Hospital
2015
ABSTRACT Parathyroid hormone (PTH)-like bioactivity, assayed as adenylate cyclase response in UMR 106-01 osteogenic sarcoma cells, was present extracts of sheep fetal and maternal parathyroid glands placenta. Preincubation with PTH(1–34) antiserum inhibited approximately 40% the bioactivity extracts, 50% but only 10% placental extract. Partial purification by chromatography yielded fractions containing PTH-like which were similar behaviour to that PTH-related protein (PTHrP) from a human...
PURPOSE: To evaluate the usefulness of a radiographic system with monochromatic synchrotron radiation to depict small vessels and peripheral secretory ducts. MATERIALS AND METHODS: Radiography various organs was tested in 14 anesthetized dogs pancreatography performed an excised human pancreas by using following system: energy level just above k absorption edge iodine as x-ray source high-definition TV high-light-sensitivity image pick-up tube camera coupled fluorescent screen detector....
The F ‐region Radio and Optical measurement of Nighttime TID (FRONT) campaign was conducted to clarify the non‐classical features traveling ionospheric disturbances (TIDs) at mid‐latitudes in May, 1998 August, 1999. A cluster all‐sky CCD cameras a GPS receiver network observed wide area ionosphere over Japan detect spatial structure temporal evolution TIDs. propagation direction nighttime detected during FRONT periods is restricted southwest. time their amplitude indicates that intensified...
Postoperative venous infarction following aneurysm surgery was studied in 48 patients with anterior communicating artery aneurysms operated on through the interhemispheric approach at acute stage of subarachnoid hemorrhage (SAH). Of 23 whose bridging veins were sacrificed during surgery, 11 (47.8%) showed frontal lobes. In contrast, only one (5.9%) 17 preserved developed cerebral edema. None eight who after Day (the day SAH defined as 0) this complication, although six them. Venous tended to...
Oligometastasis is a state in which cancer patients have limited number of metastatic tumors; with oligometastases survive longer than those polymetastases. Extensive disease (ED)-small cell lung (SCLC) considered systemic and poor survival. This study investigated whether the concept prognostic factor also applicable to ED-SCLC.We performed retrospective 141 consecutive ED-SCLC between 2008 2016. The were divided into four subgroups: group 1; solitary site one organ (n = 31), 2; 2-5 sites...
Abstract This is the first paper that reports simultaneous observations of zonal drift plasma bubbles and thermospheric neutral winds at geomagnetically conjugate points in both hemispheres. The were observed 630 nm nighttime airglow images taken by using highly sensitive all‐sky imagers Kototabang, Indonesia (geomagnetic latitude (MLAT): 10.0°S), Chiang Mai, Thailand (MLAT: 8.9°N), which are nearly stations, for 7 h from 13 to 20 UT (from 03 LT) on 5 April 2011. continuously propagated...
Background: Small cell lung cancer (SCLC) is typically categorized according to disease extent as limited or extensive, and utility of the 8th TNM classification, recommended for staging, which demonstrates a strong association with non-small-cell (NSCLC) management, remains unclear. Methods: This retrospective study included 277 consecutive SCLC patients treated at single institution between 2008 2016. Results: According currently used two-stage system, 186 (65.7%) were classified having...
Purpose: A T790M of the epidermal growth factor receptor (EGFR) is most frequently encountered mutation conferring acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC). The aim this study was assess differential clinical outcomes osimertinib therapy NSCLC patients with according type activating mutation, ie, exon 19 deletion or L858R point mutation. Patients and methods: prospective observational cohort conducted evaluate efficacy safety a major...
Topoisomerase I (TOP-I) mutations have been shown to be correlated irinotecan resistance in vitro. However, the prevalence of TOP-I germline has yet systematically elucidated. On other hand, polymorphisms UGT1A1 associated with CPT-11 toxicity clinical situations. The primary aim this study was investigate exons resistance, including untreated cancer tissue. A secondary confirm less frequent UGT1A1*28 and more UGT1A1*6 individuals Asian descent compared Caucasians African descent. 5 reported...
Concurrent chemoradiotherapy (cCRT) is the standard treatment for patients with locally advanced non-small cell lung cancer (LA-NSCLC). However, efficacy and safety of this has not been compared between who possess epidermal growth factor receptor (EGFR) mutations wild-type EGFR. The objective present study was to evaluate effect presence EGFR gene in LA-NSCLC receiving cCRT. Between January 2007 December 2013, records 64 were reviewed retrospectively. data statistically analyzed cCRT...
To determine the reason for lack of a hypoglycemic effect ethanol in fed state, on glucose turnover, liver glycogenosis, and metabolites was determined. Chronically catheterized awake freely moving rats received either (blood ethanol, 37 ± 10 mmol/liter, n = 11) or saline (n 13) intravenously 4 hr. Glucose turnover determined using primed continuous infusion [3–3H]glucose. The freeze clamped at hr glycogen metabolite measurements. Plasma (5.8 0.3 mmol/liter vs 6.3 0.2 hr, versus saline) rate...
The relationship between bone formation and vitamin D metabolism was investigated in the developing chick embryo. Fertilized White Leghorn eggs were incubated at 38 degrees C an incubator for 21 days. fresh weight calcium content of embryonic tibiae began to increase day 12 attained maximal values 19. Bone alkaline phosphatase citrate decarboxylation activities, both which represent osteoblastic activity, also days 10-12, reached 19 sharply declined thereafter. Both enzyme activities highly...