J Gao

ORCID: 0000-0001-8902-8031
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About
Contact & Profiles
Research Areas
  • Knee injuries and reconstruction techniques
  • Tendon Structure and Treatment
  • Phytochemicals and Antioxidant Activities
  • Antioxidant Activity and Oxidative Stress
  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neuropharmacology Research
  • Lower Extremity Biomechanics and Pathologies
  • Total Knee Arthroplasty Outcomes
  • Tea Polyphenols and Effects
  • Genomics and Chromatin Dynamics
  • Chromosomal and Genetic Variations
  • Shoulder Injury and Treatment
  • Osteoarthritis Treatment and Mechanisms
  • Mesenchymal stem cell research
  • Exercise and Physiological Responses
  • Biochemical effects in animals
  • Connective tissue disorders research
  • Stress Responses and Cortisol
  • Medicinal plant effects and applications
  • Smoking Behavior and Cessation
  • Laser Applications in Dentistry and Medicine
  • Peroxisome Proliferator-Activated Receptors
  • Silk-based biomaterials and applications

Jilin Medical University
2010-2024

Broomfield Hospital
2021

National Institute on Drug Abuse
2015-2018

Capital Medical University
2015

Tsinghua University
2015

Zimmer Biomet (Switzerland)
2007

German Cancer Research Center
2005

DKFZ-ZMBH Alliance
2005

Case Western Reserve University
2004

Institute of Biophysics
2002

Tendon cells have complex shapes, with many cell processes and an intimate association collagen fibre bundles in their extracellular matrix. Where contact one another, they form gap junctions. In the present study, we examined distribution of junction components phenotypically different regions rat Achilles tendon. This tendon contains a prominent enthesial fibrocartilage at its calcaneal attachment sesamoid where it is pressed against calcaneus just proximal to attachment. Studies using DiI...

10.1046/j.1469-7580.1998.19320215.x article EN Journal of Anatomy 1998-08-01

Insulin resistance and abdominal obesity are present in the majority of people with metabolic syndrome. Antioxidant therapy might be a useful strategy for type 2 diabetes other insulin-resistant states. The combination vitamin C (Vc) E has synthetic scavenging effect on free radicals inhibition lipid peroxidation. However, there few studies about how to define best more than three anti-oxidants as it is difficult or impossible test anti-oxidant every concentration each ingredient...

10.1016/j.redox.2015.06.013 article EN cc-by-nc-nd Redox Biology 2015-06-26

The 8;21 translocation is one of the most common specific rearrangements in acute myelogenous leukemia. We have identified markers (D21S65 and a Not I boundary clone, Not-42, referred to as probe B) flanking chromosome 21 breakpoint (21q22.3) that demonstrate physical linkage normal genomic DNA, by using at least three restriction endonucleases (Not I, Sac II, BssHII), are located not more than 250-280 kilobases apart. Pulsed-field gel analysis DNA from somatic cell hybrids containing...

10.1073/pnas.88.11.4882 article EN Proceedings of the National Academy of Sciences 1991-06-01

Despite large-scale anti-smoking campaigns throughout the world, number of smokers remains high and cigarette smoking continues to represent a life-threatening health risk. Until smoke-free society is achieved, reduction smoke toxins may reduce burden. Current filter techniques are limited volatile tar constituents by dilution condensation on surface. Vast quantities harmful constituents, such as polycyclic aromatic hydrocarbons, heterocyclic (aromatic) amines, free radicals reactive oxygen...

10.1191/0748233702th145oa article EN Toxicology and Industrial Health 2002-06-01

Abstract Objectives Geranylgeranylacetone, an acyclic isoprenoid, is a non-toxic inducer of heat shock protein (HSP)70. HSP70 overproduction associated with tolerance in rats. This study aimed to investigate whether geranylgeranylacetone preconditioning rats reduced heat-induced inflammation and multiple organ dysfunction. Methods Anaesthetised were given vehicle or (800 mg/kg) orally. After 48 h they exposed ambient temperature 43°C for 70 min induce heatstroke. Another group kept at room...

10.1211/jpp.62.01.0011 article EN Journal of Pharmacy and Pharmacology 2010-01-01

To optimize the combination of microsatellite loci for genetic control outbred swine stocks, 32 100 distributed among almost all chromosomes (except 12) were screened out by 1.5% agarose, 8% polyacrylamide gel and capillary electrophoresis scanning 3 miniature namely Bama (BM), Guizhou (GZ) Tibeta (TB).The mean total effective allele numbers these stocks 12.1 5.9, respectively.The heterozygosity breeds was 0.5428, 0.6978 0.7646, polymorphism information content 0.5469, 0.7296 0.7663,...

10.4238/2015.april.27.5 article EN Genetics and Molecular Research 2015-01-01

Abstract Acute stress alternates the hypothalamic paraventricular nucleus (PVN) magnocellular neuronal activity through modulation of excitatory and inhibitory synaptic inputs, leading to abnormal secretion oxytocin (OT) vasopressin (VP). However, mechanism acute modulates glutamatergic long-term potentiation (LTP) in PVN neuroendocrine cells (MNCs) is unclear. We here investigated effect on LTP MNCs, by whole-cell patch-clamp recording with biocytin staining pharmacological methods....

10.21203/rs.3.rs-3888148/v1 preprint EN cc-by Research Square (Research Square) 2024-01-29

The clinical value of tonsillectomy continues to cause much debate, despite tonsil disease representing a significant burden patients, caregivers and healthcare systems. This study assessed the long-term effect adenotonsillectomy or on Paediatric Throat Disorders Outcome Test ('T-14'), validated tool used objectively assess obstructive infective symptoms in paediatric throat disorders.Patients aged under 16 years undergoing were recruited consecutively from 2018 into our prospective...

10.1017/s0022215121002656 article EN The Journal of Laryngology & Otology 2021-10-01
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