Harriet L. Newson

ORCID: 0000-0001-8932-2804
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About
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Research Areas
  • Mycotoxins in Agriculture and Food
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Synthesis and Biological Evaluation
  • Pesticide Residue Analysis and Safety
  • Listeria monocytogenes in Food Safety
  • Trypanosoma species research and implications
  • Plasma Applications and Diagnostics
  • Crystallography and molecular interactions
  • Synthesis and biological activity
  • Analytical chemistry methods development
  • Plant biochemistry and biosynthesis
  • Biochemical and Molecular Research
  • Bacteriophages and microbial interactions
  • Chromatography in Natural Products
  • Glycosylation and Glycoproteins Research
  • Wheat and Barley Genetics and Pathology
  • Psidium guajava Extracts and Applications
  • Food Industry and Aquatic Biology
  • Insect and Pesticide Research
  • Wood and Agarwood Research
  • Axial and Atropisomeric Chirality Synthesis
  • Chemical synthesis and alkaloids
  • Indoor Air Quality and Microbial Exposure
  • Essential Oils and Antimicrobial Activity

ChemCentre
2025

Scion
2022-2025

The University of Western Australia
2016-2025

University of Guelph
2023

Victoria University of Wellington
2021

The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of African trypanosomiasis (HAT) Chagas disease. Drugs currently available to treat these neglected diseases leave much be desired. Herein we report optimization a novel class N-(2-(2-phenylthiazol-4-yl)ethyl)amides, carbamates, ureas, which rapidly, selectively, potently kill both species trypanosome. mode action compounds is unknown but does not involve CYP51 inhibition....

10.1021/acs.jmedchem.6b00442 article EN Journal of Medicinal Chemistry 2016-08-22

The protozoan parasites Trypanosoma brucei and T. cruzi cause African sleeping sickness Chagas disease, respectively. SAR for antitrypanosomal 2-[(phenylheteroaryl)ethyl]amides ureas was expanded, identifying promising oxazoles pyrazoles.

10.1039/d4md00764f article EN RSC Medicinal Chemistry 2025-01-01

This study reports for the first time fingerprinting extractives analysis of indigenous wood species Podocarpus totara from New Zealand, Eucalyptus saligna Australia and Pinus radiata imported California, USA grown in Zealand. We evaluated use analytical techniques discrimination. compared chemical extractive compounds obtained using traditional chromatographic with direct real-time–time flight-mass spectrometry (DART-TOF-MS) auxiliary chemometrics principal component analysis. The wet...

10.3390/f16020255 article EN Forests 2025-01-30

The first systematic investigation into the Baeyer–Villiger reaction of an anthraquinone is presented. double quinizarin dimethyl ether viable, directly providing dibenzo[b,f][1,4]-dioxocin-6,11-dione ring-system, which otherwise difficult to prepare. This methodology provides rapid access 1,2,3,4-tetraoxygenated benzenes, and has been exploited by application total synthesis a natural occurring benzodioxole its biphenyl dimer, both display noteworthy biological activity. Interestingly,...

10.1021/acs.joc.5b02861 article EN The Journal of Organic Chemistry 2016-03-22

Feijoa ( Acca sellowiana (O. Berg.) Burret ), also known as pineapple guava, is a member of the Myrtaceae family and well for its fruit. Chemical profiling different tissues feijoa plant has shown that they generate an array useful bioactive compounds which have health benefits such significant antioxidant activities. In this study, in vitro culture system been developed, could be explored to extract high-value from feijoa. tissue was initiated by induction callus floral buds. Sections buds...

10.3389/fpls.2023.1281733 article EN cc-by Frontiers in Plant Science 2024-01-17

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10.2139/ssrn.4800762 preprint EN 2024-01-01

The aim of this study was to explore the chemical reactive species different operating gases, and their effect on degradation aflatoxin M1 (AFM1) by cold plasma measuring concentration. Helium, at 80, 90 or 95%, used mixed with oxygen, nitrogen air. efficacy reduction improved when decreasing ratio helium in gas mixture. mixtures changed chemistry believed be due differences concentrations species. products AFM1 after treatment using a helium/air mixture pathway were identified LCMS....

10.2139/ssrn.4383282 article EN 2023-01-01

Abstract The aim of this study was to explore the chemical reactive species different operating gases, and their effect on degradation aflatoxin M1 (AFM1) by cold plasma measuring concentration. Helium, at 80, 90 or 95%, used mixed with oxygen, nitrogen air. efficacy reduction improved when decreasing ratio helium in gas mixture. mixtures changed chemistry believed be due differences concentrations species. products AFM1 after treatment using a helium/air mixture pathway were identified...

10.21203/rs.3.rs-2880238/v1 preprint EN cc-by Research Square (Research Square) 2023-05-12
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