A5002412510- Genetic diversity and population structure
- Genetic and phenotypic traits in livestock
- Fish Ecology and Management Studies
- Species Distribution and Climate Change
- Animal Behavior and Reproduction
- Oceanographic and Atmospheric Processes
- Wildlife Ecology and Conservation
- Plant and animal studies
- Genomics and Phylogenetic Studies
- Evolution and Genetic Dynamics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Mapping and Diversity in Plants and Animals
- Geophysics and Gravity Measurements
- Plant Physiology and Cultivation Studies
- Chromosomal and Genetic Variations
- Identification and Quantification in Food
- Ecology and Vegetation Dynamics Studies
- Environmental DNA in Biodiversity Studies
- Geographies of human-animal interactions
- Nicotinic Acetylcholine Receptors Study
- Chalcogenide Semiconductor Thin Films
- Avian ecology and behavior
- Genetic Associations and Epidemiology
- Animal and Plant Science Education
- Dementia and Cognitive Impairment Research
University of Rochester
2018-2025
University of California, Davis
2016-2024
Xencor (United States)
2024
Takeda (United States)
2021
Western University
2019
Harvard University Press
2019
Cornell University
2012-2017
Fisheries and Oceans Canada
2012-2017
Cornell Lab of Ornithology
2016-2017
University of Hawaiʻi at Mānoa
2013-2016
Abstract Background Sacred lotus is a basal eudicot with agricultural, medicinal, cultural and religious importance. It was domesticated in Asia about 7,000 years ago, cultivated for its rhizomes seeds as food crop. particularly noted 1,300-year seed longevity exceptional water repellency, known the effect. The latter property due to nanoscopic closely packed protuberances of self-cleaning leaf surface, which have been adapted manufacture industrial paint, Lotusan. Results genome China...
Increased fat deposition in skeletal muscle is associated with insulin resistance. However, exercise increases both intramyocellular stores and sensitivity, a phenomenon referred to as "the athlete's paradox". In this study, we provide evidence that augmenting triglyceride synthesis intrinsically connected increased sensitivity. Exercise diacylglycerol (DAG) acyltransferase (DGAT) activity muscle. Channeling fatty acid substrates into TG resulted decreased DAG ceramide levels. Transgenic...
Geographically limited dispersal can shape genetic population structure and result in a correlation between geographic distance, commonly called isolation-by-distance. Despite the prevalence of isolation-by-distance nature, to date few studies have empirically demonstrated processes that generate this pattern, largely because populations direct measures individual pedigree information. Intensive, long-term demographic exhaustive genomic surveys Florida Scrub-Jay (Aphelocoma coerulescens)...
A central goal of population genetics is to understand how genetic drift, natural selection, and gene flow shape allele frequencies through time. However, the actual processes underlying these changes-variation in individual survival, reproductive success, movement-are often difficult quantify. Fully understanding requires pedigree, set relationships among all individuals Here, we use extensive pedigree genomic information from a long-studied Florida Scrub-Jays (Aphelocoma coerulescens)...
Abstract Single‐nucleotide polymorphisms ( SNP s) are preferred over microsatellite markers in many evolutionary studies, but have only recently been applied to studies of parentage. Evaluations s and microsatellites for assigning parentage mostly focused on special cases that require a relatively large number heterozygous loci, such as species with low genetic diversity or complex social structures. We developed 120 from transcriptome assembled using RNA ‐sequencing songbird the most common...
Species ranges are set by limitations in factors including climate tolerances, habitat use, and dispersal abilities. Understanding the governing species range dynamics remains a challenge that is ever more important our rapidly changing world. can shift if environmental changes affect available habitat, or niche connectivity of changes. We tested how availability, niche, could contribute to divergent sister-species pair. The great-tailed grackle (Quiscalus mexicanus) has expanded its...
Exceptionally high thermoelectric figure of merit (zT>2), has been reported for (Ag1−ySbTe2)0.05(PbTe)0.95, which may involve the nanoscale microstructure. However, conflicting reports on same materials claim only zT 1 or less. Here we show that (Ag1−ySbTe2)0.05(PbTe)0.95 are multiphase scale millimeters despite appearing homogeneous by x-ray diffraction and routine electron microscopy. Using a scanning Seebeck microprobe, find significant variation coefficient (including both n-type...
Abstract Complex speciation, involving rapid divergence and multiple bouts of post-divergence gene flow, can obfuscate phylogenetic relationships species limits. In North America, cases complex speciation are common, due at least in part to the cyclical Pleistocene glacial history continent. Scrub-Jays genus Aphelocoma provide a useful case study because their range throughout America is structured by phylogeographic barriers with secondary contact between divergent lineages. Here, we show...
The female-specific W chromosomes and male-specific Y have proven difficult to assemble with whole-genome shotgun methods, creating a demand for new approaches identify sequence contigs specific these sex chromosomes. Here, we develop apply novel method identifying sequences that are W-specific. Using the Illumina Genome Analyzer, generated reads from male domestic chicken (ZZ) mapped them existing female (ZW) genome sequence. This allowed us segments of underrepresented in therefore likely...
Abstract Restriction site-associated DNA sequencing or genotyping-by-sequencing (GBS) approaches allow for rapid and cost-effective discovery genotyping of thousands single-nucleotide polymorphisms (SNPs) in multiple individuals. However, rigorous quality control practices are needed to avoid high levels error bias with these reduced representation methods. We developed a formal statistical framework filtering spurious loci, using Mendelian inheritance patterns nuclear families, that...
Abstract Indirect genetic effects (IGE) occur when an individual’s phenotype is influenced by variation in conspecifics. Opportunities for IGE are ubiquitous, and, present, have profound implications behavioral, evolutionary, agricultural, and biomedical genetics. Despite their importance, the empirical study of lags behind development theory. In large part, this lag can be attributed to fact that measuring IGE, deconvoluting them from direct own genotype, subject many potential pitfalls....
AbstractSystems of oppression-racism, colonialism, misogyny, cissexism, ableism, heteronormativity, and more-have long shaped the content practice science. But opportunities to reckon with these influences are rarely found within academic science, even though such critiques well developed in social sciences humanities. In this special section, we attempt bring cross-disciplinary conversations among ecology, evolution, behavior, genetics on one hand critical perspectives from humanities other...
Structural variants (SVs) are widespread in vertebrate genomes, yet their evolutionary dynamics remain poorly understood. Using 45 long-read de novo genome assemblies and pangenome tools, we analyze SVs within three closely related species of North American jays (Aphelocoma, scrub-jays) displaying a 60-fold range effective population size. We find rapid evolution architecture, including ~100 Mb variation size driven by dynamic satellite landscapes with unexpectedly long (> 10 kb) repeat...
Abstract Regional and coastal mean sea level projections in the Intergovernmental Panel for Climate Change (IPCC) Fifth Assessment Report (AR5) account only vertical land motion (VLM) associated with glacial isostatic adjustment (GIA), which may significantly under- or over-estimate rise. Here we adjust AR5-like regional VLM from Global Positioning Satellite (GPS) measurements and/or a combination of altimetry tide-gauge data, include both GIA non-GIA VLM. Our results at selected locations...
The study of hybrid zones can provide insight into the genetic basis species differences that are relevant for maintenance reproductive isolation. Hybrid also climate change, distributions, and evolution. zone between black-capped chickadees (Poecile atricapillus) Carolina carolinensis) is shifting northward in response to increasing winter temperatures but not width. This pattern indicates strong selection against with admixed genomes. Using high-resolution genomic data, we identified...
Isolation caused by anthropogenic habitat fragmentation can destabilize populations. Populations relying on the inflow of immigrants face reduced fitness due to inbreeding depression as fewer new individuals arrive. Empirical studies demographic consequences isolation are critical understand how populations persist through changing conditions. We used a 34-year and environmental dataset from population cooperatively-breeding Florida Scrub-Jays (