A5050386626- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Ocular Disorders and Treatments
- Retinal and Macular Surgery
- Silk-based biomaterials and applications
- Herpesvirus Infections and Treatments
- Retinal Development and Disorders
- Acne and Rosacea Treatments and Effects
- Glaucoma and retinal disorders
- Cytomegalovirus and herpesvirus research
- Traumatic Ocular and Foreign Body Injuries
- Laser Applications in Dentistry and Medicine
Intersectoral Research and Technology Complex Eye Microsurgery
2023-2024
Ministry of Health of the Russian Federation
2023-2024
Moscow State University of Medicine and Dentistry
2017-2024
Introduction. Idiopathic epiretinal membrane is a formation of fibrous cellular tissue in the macula. To our understanding there no data on interaction structures with each other, as well relationship them inner limiting membrane. The morphology latter during idiopathic has been scarcely studied due to absence specific immunohistochemical markers. We focused localizing and exploring components determining markers that allow identification membranes samples. Materials methods. analyzed 29...
The core target of multifocal IOLs implantation is to provide advanced visual quality at different distances without spectacle or contact lenses that can be valuable when monofocal are implanted. Patients with need spectacles for the near and intermediate distance's vision. Multifocal intraocular due optical part construction independence patients in postoperative period. aim this review was analyze modern approach several aspects correction: independence, dysphotopsia, patient satisfaction....
Human posterior corneal epithelium (corneal endothelium) has limited proliferative activity both in vivo and vitro. Disease or dysfunction these cells leads to impaired transparency of varying degrees severity, up blindness. Currently, the only effective standard treatment for endothelial is transplantation donor cornea that contains a pool healthy functionally active cells. However, there global shortage corneas, which led an unmet clinical need fact 1 patient out 10 receives surgical...
This article presents the results of studying impact recombinant spidroin hydrogel on posterior epithelial cells and human corneal keratocytes in an vitro experiment. The World Health Organization its studies has established a high prevalence injuries among population developing countries. In recent years, various technologies have been proposed to restore damaged surface cornea. use biodegradable silk-based materials, such as spidroins is one main parts scientific research regeneration....
Актуальность. Авторами данной статьи представлен новый способ препарирования мембран, отличительной особенностью которого является формирование ультратонких срезов исследуемого препарата, что позволяет более детально изучить строение эпиретинальных и внутренних пограничных удаляемых с поверхности сетчатки при хирургическом вмешательстве по поводу эпиретинального фиброза. Цель. Представить ультраструктурные особенности удаленных в ходе хирургического вмешательства мембран использованием новой...
Актуальность. На сегодняшний день вирусы группы герпеса остаются ведущим фактором инфекционной природы, поражающим роговицу человека. Так, по оценкам отечественных ученых, герпетические кератиты являются ведущей причиной роговичной слепоты среди населения России: более 66 % всей патологии связаны с контаминацией ткани вирусами герпеса. Вирус простого способен передаваться через донорский трансплантат, в связи чем предложена технология вирусной деконтаминации трансплантата роговицы на этапе...
According to the recent WHO data, 39 million people in world are blind. In developing countries cornea diseases second most common cause of blindness. Cornea transplantation remains only radical method regain lost vision for many blind around world. However, according literature reports, cadaveric donor corneas pose a potential risk herpes virus transmission recipient during penetrating keratoplasty. It is known that simplex virus-1 persisting can adversely affect graft survival up causing...
Objective : to analyze negative laboratory results of cadaver cornea donor screening during preparation corneas for transplantation according data from the internal registry donors eye bank (EB) Fyodorov Eye Microsurgery Federal State Institution and European Bank Association (EEBA) 2011 through 2015. Materials methods . Data analysis was carried out using EB EEBA annual directories. The analyzed included number eyeballs obtained, frequency incomplete tests (hemolysis EB) positive...
The aim of the study was to assess antiviral activity 7 types liquid corneal storage medium on an experimental model herpesvirus infection in vitro.The samples a caused by herpes simplex virus type 1 Vero-cell using virological and statistical research methods carried out.All studied images medium, including Borzenka-Moroz base did not have cytotoxic effect Vero cell culture. Out 4 had reliable against HSV-1 when used under therapeutic regimen (1 hour after infection) preventive (2 hours...
Background . According to the World Health Organization, corneal diseases are one of major causes blindness globally. Endothelial dystrophy is etiological factors leading diseases. The endothelium a monolayer cells with virtually no mitotic activity. When density endothelial falls below critical threshold, loses its ability regulate stromal hydration. This leads clouding and, consequently, reduced visual acuity and quality life patient. In this regard, various keratoplasty methods widely...
There are some multufocal intraocular corrections particular qualities compared to monofocal correction. Therefore, the patient’s careful selection, detail preoperative diagnosis, accurate lens power calculation necessary get optimal clinical results. disadvantages in postoperative period, such as contrast sensitivities reduction, dysphotopsia, neuroadaptation. In addition multifocal IOLs expensive. The studies include evaluating of visual acuity for different distances, defocus curve,...
Objective: to develop technologies for preoperative preparation of the posterior lamellar corneal graft based on our own formulation preservation medium optimal dehydration donor cornea and a technique cutting out an ultrathin flap using optimized method at Eye Tissue Bank. Materials methods. In series experimental studies, we obtained data hydration level cadaveric corneas that were preserved in various solutions different observation periods. Using 16 corneas, analytical weighing...
В обзоре представлено описание патофизиологических механизмов герпесвирусной инфекции. Согласно данным медицинской статистики, вирусом простого герпеса 1 типа инфицировано большинство населения планеты. развивающихся странах данный вирус является ведущей инфекционной причиной поражения роговицы. Также вирусу отводится роль одного из факторов, приводящих к отторжению трансплантата Вышеописанные патологические явления сопряжены с перестройкой клеточных систем в ответ на вирусное воздействие....