A5084319550- SARS-CoV-2 detection and testing
- Infection Control and Ventilation
- Dental Research and COVID-19
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- COVID-19 diagnosis using AI
- Cutaneous Melanoma Detection and Management
- Thermal Regulation in Medicine
- Bacillus and Francisella bacterial research
- Dermatological and COVID-19 studies
- Scientific and Engineering Research Topics
- Respiratory Support and Mechanisms
- Virus-based gene therapy research
Liverpool School of Tropical Medicine
2021-2024
Introduction. The importance of human saliva in aerosol-based transmission SARS-CoV-2 is now widely recognized. However, little known about the efficacy virucidal mouthwash formulations against emergent variants concern and presence saliva.Hypothesis. Mouthwashes containing actives will have similar inactivation effects multiple retain saliva.Aim. To examine vitro to inactivate variants.Methodology. Inactivation by or absence was assayed using ASTM International Standard E1052-20...
Disinfection efficacy tests were conducted on surface carriers inoculated with the monkeypox virus (MPXV) by applying six disinfectant solutions (and three controls) surfaces common in low-resource settings: four nonporous (stainless steel, glass, plastic, and latex) two porous (ceramic wood). Disinfectants wiped triplicate, a 1 min contact time: 0.05 0.5% sodium hypochlorite, 70% ethanol, quaternary ammonium compound (QAC)-based disinfectants, 1.4% hydrogen peroxide. MPXV was then quantified, log
Healthcare associated infections (HCAI) represent a significant burden worldwide contributing to morbidity and mortality result in substantial economic consequences equating billions annually. Although the impacts of HCAI have been felt for many years, coronavirus pandemic has had profound effect, escalating rates HCAI, even with extensive preventative measures such as vaccination, personal protective equipment, deep cleaning regimes. Therefore, there is an urgent need new solutions mitigate...
Understanding the transmission dynamics of SARS-CoV-2, particularly its transfer from contaminated surfaces (fomites) to human skin, is crucial for mitigating spread COVID-19. While extensive research has examined persistence SARS-CoV-2 on various surfaces, there limited understanding how efficiently it transfers and long survives skin. This study investigates two key aspects transmission: (1) efficiency non-porous (plastic metal) porous (cardboard) a 3D skin model (LabSkin), (2) survival...
The declaration of mpox as a Public Health Emergency International Concern highlights the need for interventions to interrupt virus transmission, including transmission via fabrics. Current World Organization guidance on clothes washing is based general consensus inactivation; however, there uncertainty about efficacy laundry detergents and disinfectants or reduction risk achieved by monkeypox (MPXV) specifically.
Abstract The role of human saliva in aerosol-based transmission SARS-CoV-2 has highlighted the need to understand potential oral hygiene products inactivate virus. Here we examined efficacy mouthwashes containing cetylpyridinium chloride (CPC) or chlorhexidine (CHX) inactivating SARS-CoV-2. After 30 seconds contact under standard aqueous conditions CPC achieved a ≥4.0log 10 PFU/mL reduction (USA-WA1/2020) titres whereas comparable CHX <2.0log reduction. Further testing with demonstrated...