A5042323155- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Electromagnetic Fields and Biological Effects
- Neural dynamics and brain function
- Atmospheric Ozone and Climate
- Muscle activation and electromyography studies
- Neuroscience and Neuropharmacology Research
- Atmospheric and Environmental Gas Dynamics
- Photoreceptor and optogenetics research
- Extracellular vesicles in disease
- Nanopore and Nanochannel Transport Studies
- Spectroscopy and Laser Applications
- Lipid Membrane Structure and Behavior
- Neurological disorders and treatments
Mayo Clinic
2024
Mayo Clinic in Florida
2020-2024
WinnMed
2023
Mayo Clinic in Arizona
2020
Abstract Objective. This study aims to characterize the time course of impedance, a crucial electrophysiological property brain tissue, in human thalamus (THL), amygdala-hippocampus, and posterior hippocampus over an extended period. Approach. Impedance was periodically sampled every 5–15 min several months five subjects with drug-resistant epilepsy using investigational neuromodulation device. Initially, we employed descriptive piecewise continuous mathematical models impedance response for...
Slow-wave sleep, defined by low frequency (<4 Hz) electrical brain activity, is a basic function affecting metabolite clearance and memory consolidation. The origin of low-frequency activity related to cortical up down states, but the underlying cellular mechanism how activities affect consolidation has remained elusive. We applied stimulation with voltages comparable in vivo sleep recordings over range frequencies cultured glial astrocytes while monitored trafficking GFP-tagged...
Abstract Objective This study aims to characterize the time course of impedance, a crucial electrophysiological property brain tissue, in human thalamus (THL), amygdala-hippocampus (AMG-HPC), and posterior hippocampus (post-HPC) over an extended period. Approach Impedance was periodically sampled every 5-15 minutes several months five subjects with drug-resistant epilepsy using experimental neuromodulation device. Initially, we employed descriptive piecewise continuous mathematical models...
Abstract Extracellular vesicles (EVs) are small membrane‐bound structures that originate from various cell types and carry molecular cargos to influence the behaviour of recipient cells. The use EVs as biomarkers for diagnosis delivery vehicles treatment in a wide range human disease is rapidly growing field research clinical practice. We hypothesized electric fields (EFs) could release content EVs. To examine this hypothesis, we developed specialized bioreactor enabling cells thrive...