A5027149477- Proteins in Food Systems
- Multiple Myeloma Research and Treatments
- Food composition and properties
- Nail Diseases and Treatments
- Oral Health Pathology and Treatment
- Microencapsulation and Drying Processes
- Hematopoietic Stem Cell Transplantation
- Polysaccharides Composition and Applications
- Microbial Metabolites in Food Biotechnology
- Chronic Lymphocytic Leukemia Research
- Synthesis and biological activity
- Cancer and Skin Lesions
- Botanical Research and Chemistry
- Biofuel production and bioconversion
- Autoimmune Bullous Skin Diseases
- Metal complexes synthesis and properties
- Acne and Rosacea Treatments and Effects
- Synthesis and Characterization of Heterocyclic Compounds
- Bone health and osteoporosis research
- Glycosylation and Glycoproteins Research
- Phytase and its Applications
- COVID-19 and Mental Health
- Mobile Health and mHealth Applications
- Acute Myeloid Leukemia Research
- Peptidase Inhibition and Analysis
National Public Health Laboratory
2024
Kathmandu University
2018-2023
Monash University
2021-2023
Dhulikhel Hospital
2018-2022
North Carolina Agricultural and Technical State University
2016-2022
South Asian University
2021-2022
Asian Institute of Technology
2018-2021
University of Puerto Rico at Carolina
2019
Greensboro College
2019
University Teaching Hospital
2018
Lentils and mungbean proteins are under-researched compared to pea soybean. (green, red black-lentils), yellow protein isolates were obtained by alkaline extraction (pH 9)-isoelectric precipitation 4.5) investigated for molecular higher-order structures using complementary novel approaches. These extracted showed comparable content but significantly greater nitrogen solubility index (NSI > 85 %) than commercial soy < 60 %). Based on weight estimations from sodium dodecyl...
The molecular structure and conformation of the plant-based proteins dominate their gelation behaviour. These aspects have been mostly overlooked for underutilised pulse such as lentils mungbean that differ structurally with soy pea proteins. Rheological textural properties heat-induced gels (LPIs) (green, red black lentils), (MBPI) yellow (YPPI) were compared commercial (CSPI) (CPPI) protein isolates. On investigation dynamic rheological parameters, critical concentration (CPC) MBPI was...
Myelofibrosis is a myeloproliferative disorder incurable with conventional strategies. Several small series have reported long-term disease-free survival (DSF) after allogeneic hematopoietic cell transplantation (HCT). In this study, we analyze the outcomes of 289 patients receiving for primary myelofibrosis between 1989 and 2002, from database Center International Bone Marrow Transplant Research (CIBMTR). The median age was 47 years (range: 18-73 years). Donors were HLA identical siblings...
Despite common use of supplemental vitamin D2 in clinical practice, the associations serum concentrations with other D metabolites and total are unclear. The aim study was to measure D3 levels examine their each D. We performed a cross-sectional analysis 679 randomly selected participants from Osteoporotic Fractures Men Study. 25-Hydroxyvitamin [25(OH)D2], 25(OH)D3, 1,25-dihydroxyvitamin [1,25(OH)2D2], 1,25(OH)2D3 were measured using liquid chromatography-tandem mass spectrometry summed...
Mungbean and lentil proteins are gaining attention for the production of high moisture extrusion (HME)-based meat- dairy-analogues. However, understanding mechanism fibrous structure formation molecular higher-order changes in HME remains limited. Globulin protein isolated from mungbean (MBPI), green (GLPI) yellow pea (YPPI) along with commercial soy (CSPI) (CPPI) isolates were investigated pasting properties using high-pressure rapid visco analyser (RVA), anisotropic structures at a...
Objective: The aim of this study is to evaluate fall rates across body mass index (BMI) categories by age group, considering physical performance and comorbidities. Method: In the Osteoporotic Fractures in Men (MrOS) study, 5,834 men aged ≥65 reported falls every 4 months over 4.8 (±0.8) years. Adjusted associations between BMI an incident were tested using mixed-effects models. Results: rate (0.66/man-year overall, 95% confidence interval [CI] = [0.65, 0.67]) was lowest youngest, normal...
ABSTRACT We investigated the associations of 3D geometric measures and volumetric bone mineral density (vBMD) proximal femur assessed by quantitative computed tomography (QCT) with hip fracture risk among elderly men. This study was a prospective case-cohort design nested within Osteoporotic Fractures in Men Study (MrOS) cohort. QCT scans 230 men (65 confirmed fractures) were evaluated Mindways' QCTPRO-BIT software. Measures that are indicative strength for femoral neck (FN) trochanteric...
5-Nitroisatin-4-(1-(2-pyridyl)piperazinyl)-3-thiosemicarbazone (Nitistpyrdlpz) and its Cu(II) complex were synthesized characterized by CHN thermal analysis spectroscopic measurements viz. UV-vis, FTIR, 1H NMR, 13C ESI-HRMS, PXRD EPR. In the complex, copper(II) ion is coordinated terdentate thiosemicarbazone anion one chloride in a distorted square planar geometry. The compounds against breast cancer cell lines; MCF-7 MDA-MB-231 epidermoid carcinoma; A431 showed that contributed to reduce...
N(4) modified copper thiosemicarbazones have been extensively studied for their anticancer potency toward various cancer cells as they exhibit less toxicity, wide spectrum of activity, non-resistance behavior and a novel mechanism action compared to that platinum complexes.5-Nitroisatin -4-thiomorpholinyl-3-thiosemicarbazone(L1), 5nitroisatin -4, 4-dimethyl-3-thiosemicarbazone(L2), (II) complexes; CuL1 CuL2 were prepared characterized by elemental analysis, FTIR, NMR, ESI-HRMS, UV-Vis, TGA,...
We analyzed the outcomes of 248 (61% male) adult recipients HLA-matched unrelated and HLA-mismatched related donor hematopoietic cell transplantation (HCT) for non-Hodgkin lymphoma (NHL) after reduced or lower intensity conditioning (RIC), reported to Center International Blood Marrow Transplant Research (CIBMTR) from 1997 2004. Median age was 52 (range: 18-72 years); 31% had a Karnofsky performance score <90. Follicular NHL (43%) major histology. Incidence grades II-IV acute...
Background: Acne beyond 25 years of age is frequently associated with hormonal derangement in women. Hormonal association provides the impetus for therapy as well underpins need blood investigations this population. Hence, we aim to estimate presence and lipid alteration female adult acne.Methods: A prospective, observational study was conducted Dhulikhel Hospital from July 2015 February 2016. Females older than acne were taken after informed consent. Total 100 patients enrolled sample size...
Background: Acne beyond 25 years of age is frequently associated with hormonal derangement in women. Hormonal association provides the impetus for therapy as well underpins need blood investigations this population. Hence, we aim to estimate presence and lipid alteration female adult acne.Methods: A prospective, observational study was conducted Dhulikhel Hospital from July 2015 February 2016. Females older than acne were taken after informed consent. Total 100 patients enrolled aftersample...
Influenza (sometimes referred to as "flu") is a contagious viral infection of the airways in lungs that affects significant portion world's population. Clinical symptoms influenza virus infections can range widely, from severe pneumonia moderate or even asymptomatic sickness. If left untreated, have more effects on heart, brain, and than respiratory tract necessitate hospitalization. This study was aimed investigate characterize all types cases prevailing Nepal analyze seasonal occurrence...