A5052520826- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- Photonic and Optical Devices
- Neural Networks and Reservoir Computing
- Optical Network Technologies
- Virus-based gene therapy research
- Diabetes and associated disorders
- Quantum Information and Cryptography
- Photodynamic Therapy Research Studies
- Immunodeficiency and Autoimmune Disorders
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Pancreatic function and diabetes
- Cell Adhesion Molecules Research
- Diabetes Management and Research
- T-cell and Retrovirus Studies
- Advanced Biosensing Techniques and Applications
- bioluminescence and chemiluminescence research
- Cancer Research and Treatments
- Animal Virus Infections Studies
- Atherosclerosis and Cardiovascular Diseases
- Viral Infectious Diseases and Gene Expression in Insects
- Microfluidic and Capillary Electrophoresis Applications
The University of Tokyo
2022-2025
Aichi Cancer Center
1967-2016
Hamamatsu University School of Medicine
1993-2011
Tohoku Medical and Pharmaceutical University
2002
Showa University
1995-1999
National Institute of Neurological Disorders and Stroke
1992
National Institutes of Health
1992
Kyushu University
1974-1992
Hamamatsu University
1977
Hamamatsu Medical Center
1976
The requirements with respect to HLA compatibility and the relative importance of matching for individual class I II alleles in transplantation hematopoietic stem cells from unrelated donors have not yet been established.
The distribution in the mouse of lymphoid cells carrying receptors for IgG or IgG‐Ag was investigated. B lymphocytes were found to have reacting with both and IgG‐Ag. Resting T did not react activated by passage through irradiated, allogeneic mice had a receptor IgG‐Ag, but IgG.
It has been found possible to separate cells according their surface anti gens by the use of antibody‐coated columns. High efficiency columns were made double‐layer principles, first coating beads with antigen followed antibody in excess. Such could be shown contain a high amount free antigen‐binding sites for relevant antigens. Lymphoid thus fractionated concentration immunoglobu lin and highly selective retention mouse B lymphocytes was observed when filtering spleen through an...
We demonstrate universal and programmable three-mode linear-optical operations in the time domain by realizing a scalable dual-loop optical circuit suitable for quantum information processing (QIP). The programmability, validity, deterministic operation of our are demonstrated performing nine different on squeezed-state pulses, fully characterizing outputs with variable measurements, confirming their entanglement. Our can be scaled up just making outer loop longer also extended to computers...
Quantum computing has been pursued with various hardware platforms and an optical system is one of the most reasonable choices for large-scale computation. In continuous-variable computation scheme, incorporation Gaussian gates a highly nonclassical non-Gaussian state enables universal quantum Although basic technologies generation have long developed, these building blocks not yet integrated in scalable fashion. Here, we integrate them to develop programmable platform that can sequentially...
Abstract Superantigens including staphylococcal enterotoxins (SE) bind to major histocompatibility complex class II molecules and interact with T cells bearing particular vβ chains. SEB was shown induce the expression of interleukin (IL)‐1β tumor necrosis factor (TNF)‐α genes in human peripheral blood monocytes HLA molecules. Monoclonal antibodies directed against HLA‐DR ‐DQ abolished SEB‐induced both EL‐1β TNF‐α genes, suggesting that mediated gene expression. Therefore, we investigated...
We present a loop-based optical processor enabling time-domain programmable beam-splitter (BS) operations for phase-sensitive non-Gaussian state. The loop itself is of high quality, allowing storage state up to seven round trips while preserving its Wigner negativity and phase coherence. perform various BS on evaluate them as transformations the state's waveforms. Our work integrates states with time multiplexing, laying foundation large-scale universal quantum information processing.
Journal Article Localization of Sucrase in the Microvillous Membrane Rabbit Intestinal Mucosal Cells Get access Yoshiki TAKESUE, TAKESUE Research Institute for Environmental Medicine, Nagoya University, and Institute, Aichi Cancer CenterNagoya Search other works by this author on: Oxford Academic PubMed Google Scholar Takato O. YOSHIDA, YOSHIDA Tatsuya AKAZA, AKAZA Yoshimi NISHI The Biochemistry, Volume 74, Issue 3, September 1973, Pages 415–423,...
Abstract Taking advantage of the reverse transcriptase‐polymerase chain reaction (RT‐PCR), we have analyzed T cell receptor γ‐chain mRNA synovial fluid γ/δ cells from patients with rheumatoid arthritis (RA) in comparison those peripheral blood mononuclear (PBMC) RA and healthy individuals. The quantitative RT‐PCR method conjunction nucleotide sequencing revealed frequent usage Vγ3 gene segment (SFMC) ( p < 0.01) which PBMC individuals occurred rarely. most expressed Vγ9 predominantly as...
Journal Article The unique nucleotide sequence of the Aβ gene in NOD mouse is shared with its nondiabetic sister strains, ILI and CTS Get access T. O. Yoshida, Yoshida Department Microbiology Immunology, Hamamatsu University School Medicine3600 Handa-cho, 431-31, Japan Correspondence to. Y Koide, as above Search for other works by this author on: Oxford Academic PubMed Google Scholar Y. Koide International Volume 2, Issue February 1990, Pages 189–192, https://doi.org/10.1093/intimm/2.2.189...
Abstract The serum complement level was studied in 94 cases of patients with myelogenous and lymphogenous leukemia, including long‐term survivors. Studies on serial changes the at exacerbation stage remission 10 acute leukemia were carried out separately. In two levels followed up during course clinical stage. Serum majority chronic remained within range healthy control levels, while wide variations noted leukemic patients, especially those exacerbation. showed a larger variation trend...
The fluorescent antibody technique with specific conjugate of antiserum to alpha-fetoglobulin was applied five hepatoma tissues, which three cases showed positive α-f globulin identified by a modified Ouchterlony immunodiffusion technique; two were negative. Various histologic patterns tumor tissue present both in and negative cases. intensity the total area fluorescence found be well correlated quantitative aspects serum globulin, but bore no relationship various tumor. also small limited...
One of the leading approaches to large-scale quantum information processing (QIP) is continuous-variable (CV) scheme based on time multiplexing (TM). As a fundamental building block for this approach, light sources sequentially produce time-multiplexed squeezed-light pulses are required; however, conventional CV TM experiments have used fixed that can only output squeezed with same squeezing levels and phases. We here demonstrate programmable source generate sequential various phases at...
Human antigen-presenting cells (APC) which present the antigen to T lymphocytes resulting in a T-lymphocyte proliferative response were found among peripheral mononuclear (MNC), by employing purified protein derivative (PPD) as soluble antigen. To assess adherence capacity of human cells, MNC separated plastic Petri dishes or nylon wool columns. Plastic nonadherent almost equivalent unseparated ability. adherent however, showed better ability than cells. On other hand, passed over columns...
Discussion and ConclusionEmbryonic skin culture of domestic rabbit was infected with Shope papilloma virus in vitro the early phase virus-cell interaction studied sequentially up to 30-hours post infection by immunofluorescence technique. The cells cultures showed a specific fluorescent reaction nucleus when stained antipapilloma antisera conjugated FITC. ratio positively about 20% whole cell population 5-6 hours after it reached maximum approximately 90% at around 11 hours. morphological...