Long Tang

ORCID: 0000-0001-9252-7122
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Pomegranate: compositions and health benefits
  • Catalytic C–H Functionalization Methods
  • Cynara cardunculus studies
  • Sulfur-Based Synthesis Techniques
  • Crystallography and molecular interactions
  • Meat and Animal Product Quality
  • Chemical synthesis and alkaloids
  • Phosphodiesterase function and regulation
  • Metal complexes synthesis and properties
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Synthesis and Biological Evaluation
  • Fluorine in Organic Chemistry
  • Synthesis and Catalytic Reactions
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Advanced Chemical Sensor Technologies
  • Synthesis and biological activity
  • Plant-derived Lignans Synthesis and Bioactivity
  • QR Code Applications and Technologies
  • Wireless Sensor Networks and IoT
  • Ideological and Political Education

Changzhou University
2011-2025

Air Force Medical University
2025

Xi'an Jiaotong University
2024

Shanghai Institute of Technology
2024

Beijing Technology and Business University
2020-2022

Institute of Chemical Industry of Forest Products
2021-2022

Chinese Academy of Forestry
2021-2022

Nanjing Forestry University
2021

Affiliated Hospital of Guilin Medical College
2018

Communication University of China
2012-2013

Objective Diabetic foot ulcer (DFU) is one of the common complications in patients with diabetes mellitus (DM). In order to find a method monitor and treat refractory DFU, ferroptosis level DFU traumatic wounds (TW) was monitored difference between them analyzed. At same time, this study further analyzed correlation levels DM severity DFU’s healing. Methods A prospective cohort from January, 2021 December, 2023 Second People’s Hospital Gansu province, which included 59 42 TW. We then used...

10.3389/fendo.2024.1412373 article EN cc-by Frontiers in Endocrinology 2025-01-14

Thioether skeletons are widely present in drugs, natural products, functional materials, and life science. In the past decade, selective C–H functionalization of thioethers has been extensively studied to construct novel thioether derivatives. This mini-review systematically introduces recent advances field direct α-C(sp3)-H thioethers.

10.1016/j.gresc.2022.02.002 article EN cc-by-nc-nd Green Synthesis and Catalysis 2022-02-28

This study was conducted to analyze volatile odor compounds and key odor-active in the fish soup using scarp bone. Five extraction methods, including solid-phase microextraction (SPME), dynamic headspace sampling (DHS), solvent-assisted flavor evaporation (SAFE), stir bar sorptive (SBSE), liquid-liquid (LLE), were compared SPME finally selected as best method for further study. The analyzed by gas chromatography-olfactometry-mass spectrometry (GC-O-MS) comprehensive two-dimensional (GC ×...

10.3390/molecules27196177 article EN cc-by Molecules 2022-09-21

Phosphodiesterase-2A (PDE2A) is a potential therapeutic target for the treatment of ganglion dysfunction-related diseases such as Alzheimer's disease, schizophrenia, cognitive impairment, anxiety, and depression. However, most current PDE2A inhibitors have moderate selectivity compared to other PDEs. In this study, we described discovery 6 novel by bioassays, molecular docking, dynamics simulations. Six molecules out 2592 compounds from L6000-Natural Compound Library inhibited with affinity...

10.1080/07391102.2025.2487193 article EN Journal of Biomolecular Structure and Dynamics 2025-04-11

ABSTRACT Urolithin A (UA) is a dibenzo[ b,d ]pyran‐6‐one polyhydroxy derivative produced as intestinal microbe metabolize ellagitannin and ellagic acid. Because of its superior anti‐inflammatory antioxidant effects, it can cure neuronal damage in variety ways play neuroprotective role. More more research has revealed that UA potential medicine for the treatment neurodegenerative diseases. Due to source limitations, insufficient achieve disease concentrations, activity inhibiting PDE2 needs...

10.1111/cbdd.70119 article EN Chemical Biology & Drug Design 2025-05-01

Metal-free C(sp3)–S bond cleavage of thioethers was achieved using NCS as a critical additive. A wide range arylmethyl were successfully transformed into aryl aldehydes with satisfactory yields in chloroform. Meanwhile, employing fluorobenzene the solvent enables selective formation dithioacetals from thioethers, achieving moderate to good yields. Notably, first prepared through metal-free and subsequent thioacetalization process. Furthermore, these simple efficient approaches also provide...

10.3390/chemistry7030089 article EN cc-by Chemistry 2025-05-29

Metal‐free and Selectfluor‐mediated C–S bond cleavage is described. This novel strategy provides a facile efficient method to access important N ‐substituted acrylamide β‐aminopropanamide derivatives with good functional group tolerance yields.

10.1002/ejoc.201900960 article EN European Journal of Organic Chemistry 2019-08-15

Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) are the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in treatment neurodegenerative diseases. As part this research, series alkoxylated 6H-benzo[c]chromen-6-one derivatives were designed and synthesized. Furthermore, their biological activities evaluated as potential PDE2 inhibitors, derivative 1f found have optimal inhibitory (IC50: 3.67 ± 0.47 μM). It also exhibited comparable activity...

10.3390/ijms22115680 article EN International Journal of Molecular Sciences 2021-05-26

As incompatibilities of mobile phone platforms, it is hard to develop application for developers on various platforms. Now, there are many cross-platform frames in the market, Phonegap considered best one. This particle describes concept and its included API components, builds Android based Phonegap, which better explains that can achieve using web technology.

10.1109/icsess.2013.6615391 article EN 2013-05-01

Abstract A manganese(II) complex of 4-(4-methylphenyl)-3,5-bis(2-pyridyl)-4H-1,2,4-triazole (MBPT) was synthesized and characterized by X-ray crystallography. [Mn(MBPT)2(H2O)2](ClO4)2 · 4H2O is a divalent mononuclear with manganese coordinated to four nitrogens from two triazole ligands oxygens water molecules in slightly distorted octahedral geometry. The ligand were tested vitro for their antibacterial activities. title showed wide range bactericidal Keywords: TriazoleManganese(II)...

10.1080/00958972.2011.576758 article EN Journal of Coordination Chemistry 2011-05-03

Lighting control system has developed from traditional control, analogy to digital and network technology is gradually used improve simplify the system. There are two protocols that ACN Art-Net. This article mainly describes DMX512, Art-Net, protocols, introduces fiber lighting

10.1109/iscid.2013.65 article EN 2013-10-01
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