A5069359435- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Pelvic and Acetabular Injuries
- Musculoskeletal pain and rehabilitation
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Spinal Cord Injury Research
- Mesenchymal stem cell research
- Spinal Hematomas and Complications
- Anesthesia and Pain Management
- Aluminum Alloy Microstructure Properties
- Bone health and osteoporosis research
- Acupuncture Treatment Research Studies
- Infectious Diseases and Tuberculosis
- Tendon Structure and Treatment
- Nerve injury and regeneration
- Bone health and treatments
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Aluminum Alloys Composites Properties
- Neuroinflammation and Neurodegeneration Mechanisms
- Scoliosis diagnosis and treatment
- Cardiac Ischemia and Reperfusion
- Osteoarthritis Treatment and Mechanisms
- Microstructure and mechanical properties
Northern Jiangsu People's Hospital
2017-2025
University of Science and Technology Beijing
2023-2024
Yangzhou University
2015-2024
University of Science and Technology of China
2024
Shandong University
2014
Fourth Affiliated Hospital of China Medical University
2014
China Medical University
2014
Hubei Provincial Hospital of Integrative Medicine
2013
Wuhan No.1 Hospital
2011-2012
South China University of Technology
2011
Stem cell-based tissue engineering in treating intervertebral disc (IVD) degeneration is promising. An appropriate cell scaffold can maintain the viability and function of transplanted cells. Injectable hydrogel has potential to be an as it mimic condition natural extracellular matrix (ECM) nucleus pulposus (NP) provide binding sites for This study was aimed at investigating effect injectable hydrogel-loaded NP-derived mesenchymal stem cells (NPMSC) treatment IVD (IDD) rats. In this study,...
Percutaneous vertebroplasty (PVP) typically involves conventional lower-viscosity cement injection via bipedicular approach. Limited evidence is available comparing the clinical outcomes and complications in treating osteoporotic vertebral compression fractures (OVCFs) with PVP using high-viscosity through unipedicular or approach.Fifty patients OVCFs were randomly allocated into two groups adopting PVP. The efficacy of was assessed by operation time, X-ray exposure incidence complications,...
In degenerative intervertebral disc (IVD), an unfavorable IVD environment leads to increased senescence of nucleus pulposus (NP)-derived mesenchymal stem cells (NPMSCs) and the inability complete differentiation from NPMSCs NP cells, leading further aggravation degeneration (IDD). Urolithin A (UA) has been proven have obvious effects in delaying cell resisting oxidative stress.To explore whether UA can alleviate elucidate underlying mechanism.In vitro, we harvested rat tails, divided into...
The art of constructing an insightful literature review manuscript has witnessed exemplar in the work Oz et al (2023), wherein concept progression harmoniously merges with figures and tables. Reflecting on retrospective data science, it is evident that well-cited articles can wield a transformative influence Journal Citation Reports Impact Factor score, as exemplified by Robert Weinberg’s landmark cancer (Hanahan Weinberg, 2011). Here, we aim to spotlight commendable contribution Tuba Oz,...
Diabetes mellitus (DM) is a dependent risk factor in the progression of intervertebral disc degeneration (IVDD). High glucose supply has negative effects on nucleus pulpous (NP) cell and mesenchymal stem (MSC) biology. However, effect hyperglycaemia biological characterization pulpous‐derived (NPMSC) not been investigated previously. Therefore, further exploration DM‐associated NPMSC biology important to better understand develop endogenous repair strategies DM patient‐associated IVDD....
Intervertebral disc degeneration (IVDD) is one of the main causes low back pain. The local environment degenerated intervertebral (IVD) increases oxidative stress and apoptosis endogenous nucleus pulposus-derived mesenchymal stem cells (NPMSCs) weakens its ability repair in IVDs. A suitable concentration 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) has been certified to reduce cell apoptosis. current study investigated protective effect potential mechanism 1,25(OH)2D3 against stress-induced...
Vertebroplasty is the most widely used method for treating osteoporotic vertebral compression fractures (OVCF). During this procedure, bone cement injected into body. Fracture and additional can occur adjacent to treatment site. Thus, we studied factors causing such after vertebroplasty calculated appropriate amount of inject.From September 2012 March 2016, 187 patients with OVCF undergoing were selected, 112 complete follow-up information selected. Of these, 28 had (refracture group) during...
Purpose: To investigate the protective effect of naringin (Nar) on H2O2-induced apoptosis nucleus pulposus-derived mesenchymal stem cells (NPMSC) and potential mechanism in this process.Methods: Rat NPMSC were cultured MSC culture medium or with different concentrations H2O2. Nar combination LY294002 was added into to effects Nar. Cell viability evaluated by cell counting kit-8 (CCK-8) assay. The rate determined using Annexin V/PI dual staining terminal deoxynucleotide transferase-mediated...
<title>Abstract</title> Introduction: Approximately 30% of patients with rheumatoid arthritis (RA) do not respond to tocilizumab (TCZ). This study aimed predict TCZ response using machine learning models trained on clinical data. Methods Baseline and follow-up data from RA treated were collected. Seven different (logistic regression, K-nearest neighbor algorithm, random forest, support vector machine, decision tree, gradient boosting, boosting algorithm) the treatment across imaging stages...