A5034223700- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
- SARS-CoV-2 and COVID-19 Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Rate Variability and Autonomic Control
- Bacteriophages and microbial interactions
- SARS-CoV-2 detection and testing
- COVID-19 and healthcare impacts
- Cardiovascular Health and Disease Prevention
- Diabetic Foot Ulcer Assessment and Management
- Streptococcal Infections and Treatments
- Blood Pressure and Hypertension Studies
- Cholesterol and Lipid Metabolism
- Gout, Hyperuricemia, Uric Acid
- Adipokines, Inflammation, and Metabolic Diseases
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Antibiotic Resistance in Bacteria
- Autoimmune Neurological Disorders and Treatments
- Reproductive tract infections research
- Peripheral Neuropathies and Disorders
- COVID-19 and Mental Health
Comenius University Bratislava
2016-2025
University Hospital Bratislava
2015-2022
Temple University
2022
Temple College
2022
Medical University of Warsaw
2022
Detská Fakultná Nemocnica s Poliklinikou
2017
Abstract Background Covid-19 is a disease with high morbidity and mortality among elderly residents of long-term care facilities (LTCF). During an outbreak SARS-CoV-2 infection in the LTCF effective screening tool essential to identify patients at risk for severe disease. We explored role interleukin 6 (IL-6) as predictor during one Slovakia. Methods conducted retrospective data analysis cases COVID-19, diagnosed Slovakia between April 11, 2020, May 5, 2020. Within 24 h after diagnosis...
Abstract The emergence of a novel SARS-CoV-2 B.1.1.7 variant sparked global alarm due to increased transmissibility, mortality, and uncertainty about vaccine efficacy, thus accelerating efforts detect track the variant. Current approaches include sequencing RT-qPCR tests containing target assay that fails or results in reduced sensitivity towards Since many countries lack genomic surveillance programs failed assays unrelated variants similar mutations as B.1.1.7, we used allele-specific PCR,...
Streptococcal toxic shock syndrome (STSS) is a serious and potentially fatal complication of invasive Streptococcus pyogenes (Group A Streptococcus, GAS) infection, often stemming from severe soft tissue infections. While uncommon, tonsillitis can also lead to STSS, with lethality rates reported as high 70%. We present three cases patients diagnosed who developed STSS. Point-of-care testing for GAS antigens was utilized facilitate rapid diagnosis. In all cases, the characteristic clinical...
Abstract During SARS-CoV-2 infection, the virus transforms infected host cell into factories that produce new viral particles. As infection progresses, cells undergo numerous changes in various pathways. One of these is occurrence a cytokine storm, which leads to severe symptoms. In this study, we examined transcriptomic caused by COVID-19 analyzing RNA-seq data obtained from COVID-19-positive patients as well COVID-19-negative donors. were collected for purpose identification potential...
Coronavirus disease 2019 (COVID-19) might be complicated by various non-respiratory conditions, including encephalitis. Encephalitis in COVID-19 represents a heterogenous group of diseases with variable aetiology. Autoimmune encephalitis (AIE) is the least common but one most severe causes encephalopathy COVID-19. AIE rare that associated different types autoantibodies mostly directed against neuronal antigens. Anti-Sry-like high mobility box (SOX1) have been described clinical Lambert-Eaton...
Body weight changes are associated with significant variations in blood pressure (BP). mass modifications may, therefore, influence hypertension control primary care.Patients a history of essential arterial were observed for 12 months. Anthropometric data and clinical BP evaluated at the time recruitment after months follow-up. The association between (body index) BMI change was analyzed by logistic regression.Sixteen thousand five hundred sixty-four patients recruited, while 13,631 (6336...
We examined in vitro antioxidant capacity of polyphenolic extract obtained from the wood oak Quercus robur (QR), Robuvit, using TEAC (Trolox equivalent capacity) method and effect its intake on markers oxidative stress, activity enzymes, total plasma 20 healthy volunteers. Markers damage to proteins, DNA, lipids activities Cu/Zn-superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) were determined erythrocytes. have found an Robuvit 6.37 micromole Trolox equivalent/mg...
Majority of studies that focused on the influence abdominal obesity lipoprotein profile, were conducted in fasting conditions. The effects visceral fat accumulation postprandial concentrations have not yet been studied details. We therefore profile otherwise healthy men and women with their comparison control group volunteers normal waist circumference. concentration classes subclasses was measured before 4 hours after a standard meal by linear polyacrylamide gel electrophoresis. A...
Background and aims. Arterial hypertension doubles the risk of coronary heart disease, kidney failure, peripheral arterial disease. Less variation in diurnal ambulatory blood pressure monitoring (ABPM) patterns may affect mortality outcome. Therefore, as occurs over 95% older subjects, prognostic value dipping status hypertensive patients will be assessed. Method. The retrospective study group consisted 170 patients, aged 75–84 years, enrolled years 2005 to 2007. Baseline measures included...
The aim of this study was to evaluate the vasodilatation and vasomotion response local heating in cutaneous microcirculation ankle, dorsum foot forearm. Recently, it has been suggested that differs between forearm leg.Twenty-nine young healthy adults were recruited. They underwent measurement by laser Doppler flowmetry (LDF) three sites body (ankle, foot, forearm). Percentage change median flow skin before after provocation normalised perfusion maximal dilation (cutaneous vascular...
Our goal was to investigate the effect of short term exercise on fasting and postprandial lipoprotein profile.Healthy sedentary men exercised 20 min for four days. The intensity modulated maintain 75-80 % a calculated HRmax. Before after program, (4 h standard meal) concentrations subfractions were measured by an electrophoresis in polyacrylamide gel total TAG, LDL HDL enzymatic colorimetric method. After 2 days rest, fractions determine persistency changes profile.4 physical led...
Abstract Background The emergence of a novel SARS-CoV-2 variant concern called B.1.1.7 lineage sparked global alarm due to evidence increased transmissibility, mortality, and uncertainty about vaccine efficacy, thus accelerating efforts detect track the variant. Current approaches include sequencing RT-qPCR tests containing target assay that fails or results in reduced sensitivity towards Aim Since many countries lack robust genomic surveillance programs failed assays multiple unrelated...
Chronic prostatitis (CP) is a common inflammatory condition of the prostate that estimated to effect 2%-10% world's male population. It can manifest as perineal, suprapubic, or lower back pain and urinary symptoms occurring with either recurrent bacterial infection [chronic (CBP)] in absence evidence pelvic syndrome (CPPS)]. Here, case 39 years-old CBP patient, we report first successful use bacteriophage-derived muralytic enzyme (endolysin) treat resolve disease. Bacteriological analysis...
Coronavirus infection disease 2019 (COVID-19) has been linked to the development of various autoimmune disorders. Lofgren syndrome, consisting bilateral pulmonary hilar lymphadenopathy, erythema nodosum and polyarthritis, is a rare that represents an acute form sarcoidosis. We present case syndrome developing in close temporal association with COVID-19. Clinical presentation consisted fever, lung arthralgias nodosum. Hilar lymph node biopsy revealed pathology consistent Three weeks prior...
Klebsiella pneumoniae is an extremely rare case of the Lemierre syndrome, which characterized as septic thrombophlebitis jugular vein a consequence oropharyngeal infection. We present unique syndrome caused by pneumoniae, complicated epidural abscess. The patient presented with fever, severe nuchal pain and stiffness mild sore throat headache. Computed tomography revealed neck abscess localized dorsally to left mandibular ramus continuing caudally along sternocleidomastoid muscle, thrombosis...
The syndrome of limbic encephalitis is a severe clinical condition with heterogenous aetiopathogenesis. A common pathogen causing the infectious herpes simplex virus (HSV), but rare cases caused by Treponema pallidum have also been reported. We present case 46-year-old man who presented sudden onset headaches, nausea, vomiting, and short-term loss consciousness clonic convulsions subsequent disorientation aphasia. Examination cerebrospinal fluid (CSF) revealed lymphocytic pleocytosis...
<title>Abstract</title> <bold>Background: </bold>Covid-19 is a disease with high morbidity and mortality among elderly residents of long-term care facilities (LTCF). During an outbreak SARS-CoV-2 infection in the LTCF effective screening tool essential to identify patients at risk for severe illness death. We explored role interleukin 6 (IL-6) as predictive factor during Covid-19 one Slovakia.<bold>Methods: </bold>We conducted retrospective data analysis all laboratory-confirmed cases...
Abstract Background Faecal microbial transplantation (FMT) is currently the most effective treatment of recurrent Clostridioides difficile infection (CDI). However, up to 20% patients experience further recurrences after single FMT. The mechanisms that lead FMT failure and its risk factors are poorly understood. Comorbidity one standard antibiotic therapy CDI. It not known if comorbidity also associated with failure. Methods We conducted a prospective observational cohort study in order...