A5015109372- Fluoride Effects and Removal
- Bone and Dental Protein Studies
- Oral microbiology and periodontitis research
- Oral health in cancer treatment
- Hematological disorders and diagnostics
- Bone Metabolism and Diseases
- Per- and polyfluoroalkyl substances research
- dental development and anomalies
- Anesthesia and Neurotoxicity Research
- Esophageal and GI Pathology
- Oral Health Pathology and Treatment
- Dental Health and Care Utilization
University of California, San Francisco
2017-2022
Center for Children
2022
Niigata University
2020
Abstract Background Previous studies have shown a correlation between fluoride concentrations in urine and community water concentrations. However, there are no of the relationship fluoridation, urine, serum, amniotic fluid pregnant women US. The aim this study was to determine maternal (MUF), adjusted for specific gravity (MUF SG ), serum (MSF), (AFF) during pregnancy, fluoridation Northern California. Methods Archived samples collected from second trimester California 47 different...
Fluorosed maturation stage enamel is hypomineralized in part due to a delay the removal of matrix proteins inhibit final crystal growth. The protein likely related reduced expression kallikrein-related peptidase 4 (KLK4), resulting proteinase activity that found fluorosed enamel. Klk4 transcription known be regulated other cell types by androgen receptor (AR) and progesterone receptors (PR). In this study, we determined possible role fluoride down-regulation KLK4 through changes AR PR....
Abstract Background Ingestion of fluoride in drinking water has been shown to result increased cellular markers inflammation rodent models. However, the approximately 5–10 × increase concentrations required rat and mouse models obtain plasma similar those found humans made relevant comparisons animal human studies difficult assess. As an white blood cell count (WBC) is a marker humans, we used available NHANES survey data assess associations between levels U.S. counts children adolescents....
Background Hematopoietic cell transplantation (HCT) is a potentially curative therapy for wide range of pediatric malignant and nonmalignant diseases. However, complications, including blood stream infection (BSI) remain major cause morbidity mortality. While certain bacteria that are abundant in the oral microbiome, such as S. mitis , can BSI, role microbial community etiology BSI not well understood. The finding use xylitol wipes, which specifically targets cariogenic mutans associated...
Amel, the gene encoding amelogenin protein involved in enamel formation, is highly alternatively spliced. When exon4 excised, it can form a mature miRNA (miR-exon4) that has previously been suggested to indirectly regulate expression of Runt-related transcription factor 2 (Runx2) bone development ameloblasts and osteoblasts. However, precise mechanism this regulation unclear. In study, we aimed identify direct targets miR-exon4. The family nuclear I/A (NFI/A) known negatively Runx2 among...
Abstract Background: Ingestion of fluoride in drinking water has been shown to result increased cellular markers inflammation rodent models. However, the approximately 10x greater concentrations required by rat and mouse models obtain blood similar those found humans, made relevance these animal studies difficult assess. Increased white cell count is a marker therefore we used available 2013-2016 NHANES survey data, which includes both counts plasma concentrations, explore relationship...