Photodynamic therapy (PDT) is a popular treatment for nonmelanoma skin cancer with clearance rates of between 70% and 100%. Although reported to have superior cosmetic outcome, the inconvenience hospital visits discomfort during are considered drawbacks.To present an open pilot study low-irradiance, potentially disposable, lightweight, organic light-emitting diode (OLED), which area-emitting light source (2 cm diameter), suitable ambulatory PDT.Twelve patients Bowen's disease (eight)...

<b>Background:</b> Segmental vitiligo (SV) and generalized (GV) are perceived to evolve by different mechanisms, the former with unspecified neural mechanisms latter melanocyte specific autoimmune mechanisms. However, two diverse difficult reconcile in cases of mixed vitiligo. To test possibility a common pathogenesis, we reviewed clinical histopathological features SV GV. <b>Materials Methods:</b> As part an ongoing study on like lesions, over 10 year period from 2002 2011, biopsies were...

'"Inflammatory vitiligo" cases with clear lichenoid infiltrates have been reported. However, the inflammatory nature of common vitiligo has not gained wide acceptance because its benign appearance and scanty cellular infiltrates. We observed in our patients a few lesions mild erythema, scaling marginal hyperpigmentation which were suspected to be inflammatory. This study was conducted assess histological features prevalence such marginally active lesions, comparison vitiligo.Two hundred ten...

Oral lichen sclerosus (LS) has been considered uncommon and involvement of lips extremely rare. We reviewed the clinical histologic features 72 cases LS with oral/genital involvement, seen in our institute from 2002 to 2007.Lichen was diagnosed exclusive genital lesions 45, lip 20, orogenital seven cases. Fifteen 27 histologically confirmed were as early inflammatory or presclerotic, eight intermediate/progressive, four late resolved lesions. Lip presented asymptomatic vitiligoid 70% dermal...

Ultraviolet A1(UVA1) phototherapy is increasingly being used in the treatment of morphea, atopic dermatitis, lupus and some other recalcitrant dermatoses. We present a retrospective review our experience with this modality.To evaluate response rates for various dermatoses adverse effects UVA1 phototherapy.We reviewed notes along electronic and/or paper case records all patients treated from October 1996 to December 2008.A total 269 (outcomes available 247) had 361 courses (treatment data 317...

Many case studies of lichen sclerosus (LS) have reported an association vitiligo. However, such is not from larger vitiligo, which happens to be a common disease. Autoimmune etiology suspected in both LS and vitiligo has been considered as the reason for their some patients. It also suggested that lichenoid inflammation may trigger autoimmune reaction against melanocytes.To test this association, we reviewed clinical histological features 266 cases 74 concurrent study diseases.All...

<b>Background:</b> Acral or acrofacial vitiligo (AFV) with bilateral lesions over the extremities and face is considered as a transitional form that may progress to generalized vitiligo. Oral genital mucosal are often integral this pattern. Lichen sclerosus (LS) in milder expression, results oral vitiligoid depigmentation without textural changes thus needs be differentiated from AFV. <b>Materials Methods:</b> We reviewed 217 cases of AFV recorded period 12 years. <b>Results:</b> One hundred...

Background Early inflammatory lesions of lichen sclerosus are histopathologically difficult to diagnose until the hallmark disease i.e., papillary sclerosis becomes visible in histological sections. Pre-sclerotic and late or resolved phases have not been extensively studied. Methods We retrospectively reviewed all cases diagnosed as genital over a ten-year period from 2006 2016, correlating clinical findings with features. Results A total 133 (90 males 43 females) were identified. Both...

We have reported segmented lesions in acral vitiligo as well generalized and thereby proposed somatic mosaicism a predisposing feature all forms of vitiligo. This study is further attempt to characterize understand such by screening large series patients.We searched our electronic archives (from 2002 2014) identified/reviewed the photos 615 patients inclusive clinical types. Over 3500 photographs were screened for patterns that repeatedly seen two or more composite picture these marked on...

Keratoacanthoma centrifugam marginatum (KCM) is a rare variant of the (KA) form squamous cell carcinoma with only 30 cases reported to date. We report case KCM arising in long-standing vitiligo lesion chronically exposed sunlight. Over years, lesions gradually evolved into sclerotic plaques and subsequently developed one plaques.

Acquired reactive perforating collagenosis (ARPC) is one of the four acquired dermatoses. The condition characterized by transepidermal elimination altered collagen. These are rare and underdiagnosed clinical entities a few studies available in Indian literature. present study described 15 patients ARPC with underlying comorbidities response to systemic antihistamines, doxycycline, topical clobetasol propionate. Of total patients, 10 were men other five women. Except two diabetes mellitus...

"Interface dermatoses" are defined as inflammatory dermatoses primarily affecting the interface elements along dermoepidermal junction, resulting in epidermal basal cell damage. This damage can be of two forms: vacuolar/hydropic degeneration and filamentous (resulting Civatte bodies). may associated with a range secondary (atrophy to hypertrophy) dermal changes (varying from simple effacement rete ridges diffuse fibrosis/sclerosis). With so many variables, dermatitis" per se is not diagnosis...

Abstract Background: Menstrual health management is influenced by social and cultural factors, as well knowledge gaps. Poor hygiene practices can negatively affect academic performance outcomes. Materials Methods: A survey was conducted among 1350 adolescent girls in urban public schools Visakhapatnam, India. Results: The found positive progress menstrual management, but some challenges remain. While 81.7% of reported having enough sanitary materials, only 66.1% had access to soap water for...