A5051303488- Protist diversity and phylogeny
- Microtubule and mitosis dynamics
- Heat shock proteins research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Genetic and Kidney Cyst Diseases
The Third People's Hospital of Dalian City
2020-2022
BACKGROUND:Centrosome amplification is recognized as a hallmark of cancer. Kinesin family member C1 (KIFC1), centrosome-clustering molecule, essential for the viability extra centrosome-bearing cancer cells and may be basis progression ovarian However, its biological function mechanism in have not yet been studied. MATERIAL AND METHODS:Quantitative reverse-transcription polymerase chain reaction was performed to detect levels KIFC1 centrosome protein E (CENPE). Further, cell analyzed with...
Objective. The objective is to explore the action and mechanism of circ_0109046 on malignant phenotypes ovarian cancer cells. Methods. Circ_0109046 miR-338-3p expression were detected by quantitative real-time polymerase chain reaction (qRT-PCR). In vitro assays conducted investigate cell growth metastasis. Western blotting was utilized contents apoptosis-related markers. binding between validated using dual-luciferase reporter assay. Results. increased, while content decreased in tissues....