A5035445427- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Ocular Infections and Treatments
- Dermatology and Skin Diseases
- Ocular Diseases and Behçet’s Syndrome
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Respiratory and Cough-Related Research
- nanoparticles nucleation surface interactions
- Inhalation and Respiratory Drug Delivery
- Mesenchymal stem cell research
- Immune Response and Inflammation
- Food Allergy and Anaphylaxis Research
- Atherosclerosis and Cardiovascular Diseases
- Herpesvirus Infections and Treatments
- Asthma and respiratory diseases
- Sirtuins and Resveratrol in Medicine
- Systemic Lupus Erythematosus Research
- Microencapsulation and Drying Processes
- Autoimmune and Inflammatory Disorders
- Reproductive System and Pregnancy
- Additive Manufacturing and 3D Printing Technologies
- Allergic Rhinitis and Sensitization
- IL-33, ST2, and ILC Pathways
- Retinal and Optic Conditions
Łukasiewicz Research Network – PORT Polish Center for Technology Development
2018-2023
Jagiellonian University
2015-2023
Łukasiewicz Research Network
2019
Wroclaw Research Centre EIT+ (Poland)
2018
University of Zurich
2015
CK-CARE
2015
(1) Background: Tannic acid is a plant-derived polyphenol showing antiviral activity mainly because of an interference with the viral adsorption. In this work, we tested whether modification silver nanoparticles tannic (TA-AgNPs) can provide microbicide additional adjuvant properties to treat genital herpes infection. (2) Methods: The mouse model vaginal simplex virus 2 (HSV-2) infection was used test immune responses after treatment primary TA-AgNPs, and later, re-challenge virus. (3)...
Regulatory T (Treg) cells have emerged as key players in the maintenance of immune homeostasis. Although significant progress has been made recent years to define Treg surface markers involved with or identifying their suppressive function, there remains much be elucidated, and many questions persist. This study determined expression on human peripheral conventional (Tconv) a steady state after activation gain insight into mechanism action more precisely characterize this regulatory...
Introduction Renal involvement is one of the most serious manifestations systemic lupus erythematosus, but non-invasive assessment inflammatory response in kidneys challenging. In this study we aimed to validate markers active nephritis (LN) using urine immune profiling. Methods Urine and serum cytokines (17-plex array) mRNA expression (∼40 glomerular injury genes) were measured LN patients with disease ( n = 17) during remission 16) healthy subjects 18). Results levels CCL2, CCL5 CXCL10...
Endocrine disorders, including equine metabolic syndrome (EMS), are a serious issue in veterinary medicine and horse breeding. Furthermore, EMS was shown to affect the cytophysiological properties of adipose-derived stem cells, reducing their therapeutic potential. However, it that those cells can be rejuvenated while using combination two chemicals: 5-azacytydine (AZA) resveratrol (RES). In present study, we decided evaluate immunomodulatory AZA/RES-treated (ASC) isolated from horses...
Glucose-derived mannose is a common component of glycoproteins, and its deficiency leads to severe defect in protein glycosylation failure basic cell functions. In this work, we show that metabolism essential for IFN-γ production by mouse Th1 cells. addition, demonstrate the susceptibility cells glycolysis restriction depends on activation conditions under diminished glycolytic flux, availability becomes limiting factor expression. This study unravels new role glucose differentiation process...
In this study, high energy ball milling and nano spray drying were used to prepare amorphous solid dispersions of bosentan in copovidone for the first time. particular, impact polymer on amorphization kinetics was investigated. Copovidone shown facilitate upon milling. As a result, dispersed at molecular level, forming dispersions, regardless ratio compounds. The similarity between values adjustment parameter that describes goodness fit Gordon-Taylor equation experimental data (K = 1.16)...
In patients, an increase in the population of Th17-secreting cells negatively correlated with abundance both IFN-γ-producing and T regulatory as well suppressor cells, regarding all phenotypes studied. Although a strong dependence PB Th1 cell compartment on duration disease was observed, it limited to subgroup patients macular edema only. The frequency B unchanged compared controls.In pars planitis, alterations lymphocyte distribution affect primarily repertoire. imbalance Th1/Th17/Treg...
In this study, our attention was focused on the impact of coamorphization process bosentan monohydrate in presence copovidone. particular, polymer amorphization kinetics upon high energy ball milling described for first time. Copovidone found to facilitate and amorphous solid dispersions could be formed regardless proportion these compounds. The Gordon-Taylor equation used establish strength interactions between copovidone their binary glassy solutions. Then, influence nano spray drying...