A5057529597- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Metabolomics and Mass Spectrometry Studies
- Cancer-related molecular mechanisms research
- Bladder and Urothelial Cancer Treatments
- Stoma care and complications
- Anorectal Disease Treatments and Outcomes
- Cancer Cells and Metastasis
- Ureteral procedures and complications
- Microbial Metabolism and Applications
- Pharmacological Effects of Natural Compounds
Tianjin First Center Hospital
2025
Tianjin Medical University
2025
Nankai University
2023-2025
Tianjin People's Hospital
2022-2024
Introduction Lateral lymph node (LLN) metastasis in rectal cancer significantly affects patient treatment and prognosis. This study aimed to comprehensively compare the performance of various predictive models predicting LLN metastasis. Methods In this retrospective study, data from 152 patients who underwent lateral dissection were collected. The cohort was divided into a training set (n=86) Tianjin Union Medical Center (TUMC), two testing cohorts: (TUMC) (n=37) Gansu Provincial Hospital...
The aim of this study was to explore the clinical value a radiomics prediction model based on T2-weighted imaging (T2WI) and indexes in predicting lateral lymph node (LLN) metastasis rectal cancer patients. This retrospective analysis 106 patients who had undergone LLN dissection. risk factors for were selected by multivariable logistic regression indicators features extracted from pelvic T2WI least absolute shrinkage selection operator algorithm backward stepwise method adopted feature...
Objective. The aim of this study was to explore the potential biological mechanisms coix seed in treatment colorectal cancer (CRC) based on network pharmacology analysis. Methods. active components and their action targets were retrieved from Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform(TCMSP). disease related CRC obtained DisGeNET database. intersection drug selected, a component-target-disease built using Cytoscape 3.8.0 tool. A global core target protein...
Objective. This study aimed to explore the genes regulating lymph node metastasis in colorectal cancer (CRC) and clarify their relationship with tumor immune cell infiltration patient prognoses. Methods. The data sets of CRC patients were collected through Cancer Gene Atlas database; differentially expressed (DEGs) associated screened; a protein–protein interaction (PPI) network was constructed; top 20 hub selected; Ontology functions Kyoto Encyclopedia Genes Genomes pathways enriched...