- Thyroid Cancer Diagnosis and Treatment
- Nasolacrimal Duct Obstruction Treatments
- Ophthalmology and Eye Disorders
- Radiation Dose and Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Ocular Surface and Contact Lens
- Radiation Therapy and Dosimetry
Endocrinology Research Center
2024
Federal State Scientific Institution Research Institute of Eye Diseases
2023
National Research Nuclear University MEPhI
2021-2022
Secondary acquired lacrimal duct obstruction (SALDO) is one of the complications radioiodine therapy. SALDO formed a few months after therapy if there sufficient uptake radioactive iodine by nasolacrimal duct. To date, risk factors leading to are unclear. The objective was determine correlation between tear production level and iodine-131 in ducts.Basal reflex studied 64 eyes prior with drug-induced hypothyroidism. condition ocular surface assessed using Ocular Surface Disease Index (OSDI)...
Within the framework of article, authors analyzed available information about damage to lacrimal apparatus during radionuclide therapy. In focus article lesions production system, main and accessory glands, as well drainage are considered. It was found that is characteristic 131 I therapy for thyroid cancer, radioligand using anti-PSMA antibodies labeled with 177 Lu 225 Ac. Lu-PSMA Ac-PSMA may gland formation a clinically pronounced "dry eye syndrome". The pathogenesis such associated...
BACKGROUND: Lacrimal glands and lacrimal pathways are one of the main undesirable targets during radionuclide therapy using I-131, namely, in 24% cases, secondary obliteration occurs [1]. In legislation Russian Federation field atomic energy use, there a number administrative documents obliging to keep records control individual radiation doses with provision data unified system for monitoring citizens. At same time, statistical analysis does not include systematic accounting internal...
Deterministic effects of medical exposure to ionising radiation can be associated with both the effectiveness treatment and adverse drug reactions it. The latter may drastically deteriorate quality life a patient after radionuclide therapy. In addition, regulations Russian Federation require indicating effective dose as measure damage (risk), but presence deterministic effect in individual organs tissues complicates monitoring recording doses. aim study was investigate radiopharmaceuticals...
Leonidas D. Marinelli is the greatest Italian-born American radiological physicist. Thanks to his efforts, we have an idea of effect radiation on body; in medical practice a unique treatment for thyroid cancer with help radioisotope I 131 has appeared. The article describes detail life path and formation scientist, which deserves special attention from readers, since came success thanks own perseverance work, despite all difficulties obstacles, he received higher education America, found...