A5048515502- Ovarian function and disorders
- Reproductive Biology and Fertility
- Endometriosis Research and Treatment
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Uterine Myomas and Treatments
- Medical and Health Sciences Research
- Breast Cancer Treatment Studies
- Gynecological conditions and treatments
- Reproductive System and Pregnancy
- Cancer survivorship and care
- Estrogen and related hormone effects
- Ovarian cancer diagnosis and treatment
- Sperm and Testicular Function
- BRCA gene mutations in cancer
- Cardiovascular Issues in Pregnancy
- Cancer Treatment and Pharmacology
- Prenatal Screening and Diagnostics
- Hypothalamic control of reproductive hormones
- Cancer-related cognitive impairment studies
- Virus-based gene therapy research
- Ethics and Legal Issues in Pediatric Healthcare
- Health and Medical Studies
- RNA Interference and Gene Delivery
- Medical History and Research
Klinik für Frauenheilkunde
2013-2024
Kempten University of Applied Sciences
2015-2024
Universität Ulm
2005-2022
Klinikverbund Südwest
2020-2021
University of Lübeck
1998-2011
University Hospital Schleswig-Holstein
2003-2011
Ludwig-Maximilians-Universität München
2004-2011
Women's Hospital
2011
University of Regensburg
2011
German Breast group
2011
European results of assisted reproductive techniques from treatments initiated during 2004 are presented in this eighth report.Data were mainly collected existing national registers. From 29 countries, 785 clinics reported 367,066 treatment cycles including: IVF (114,672), ICSI (167,192), frozen embryo replacement (FER, 71,997), egg donation (ED, 10 334), preimplantation genetic diagnosis/screening (PGD/PGS, 2701) and vitro maturation (IVM, 170). Overall, represents only a marginal increase...
Purpose Observational studies suggested that luteinizing hormone–releasing hormone agonists (LHRHa) might prevent premature ovarian failure resulting from adjuvant chemotherapy in premenopausal patients. We aimed to test the efficacy of function preservation with LHRHa goserelin patients breast cancer. Patients and Methods In a prospective, randomized, open-label, controlled multicenter study, 60 younger than age 46 years hormone-insensitive cancer were allocated receive...
Replacing GnRH agonist cotreatment for the prevention of a premature rise in LH during ovarian stimulation vitro fertilization (IVF) by late follicular phase administration antagonist may render supplementation luteal redundant, because known rapid recovery pituitary function after cessation. This randomized two-center study was performed to compare nonsupplemented characteristics three different strategies inducing final oocyte maturation. Forty patients underwent using recombinant (r-)FSH...
European results of assisted reproductive techniques (ARTs) from treatments initiated during 2003 are presented in this seventh report.Data were mainly collected already existing national registers. From 28 countries, 725 clinics reported 365 103 treatment cycles with: IVF 132 932, ICSI 162 149, frozen embryo replacement (FER) 60 412, oocyte donation (OD) 7548, PGD/PGS 1956 and IVM 109. Overall, represents a 13% increase since 2002. For the third time, on data intrauterine inseminations...
European results of assisted reproductive techniques (ART) from treatments initiated during 2002 are presented in this sixth report. Data was mainly collected already existing national registers. From 25 countries, 631 clinics reported 324,238 treatment cycles with: IVF 122,634, ICSI 135,048, frozen embryo replacement (FER) 57 162, egg donation (ED) 7677, preimplantation genetic diagnosis/screening (PGD/PGS) 1563 and vitro maturation (IVM) 154. Overall represents a 12% increase since year...
The multicenter, randomized, phase IV, intergroup AGO-B WSG PreCycle trial (NCT03220178) evaluated the impact of CANKADO-based electronic patient-reported outcome (ePRO) assessment on quality life (QoL) in hormone receptor-positive, human epidermal growth factor receptor 2-negative locally advanced or metastatic breast cancer (MBC) patients receiving palbociclib and an aromatase inhibitor + fulvestrant. CANKADO PRO-React, a European Union-registered medical device, is interactive autonomous...
A total of 346 women with normal ovulatory function was stimulated human menopausal gonadotrophins (HMG) to attain ovarian stimulation for IVF or intracytoplasmic sperm injection (ICSI). Stimulation HMG started on cycle day 2 3. After 6 days stimulation, Cetrorelix in its minimum effective multiple dose 0.25 mg/day, administered daily until induction ovulation. In total, 333 patients (96.2%) reached the HCG administration, and 324 (93.6%) underwent oocyte retrieval. mean 25.2 ampoules...
Suppression of endogenous LH production by mid-follicular phase GnRH-antagonist administration in controlled ovarian hyperstimulation protocol using recombinant (rec) FSH preparations void activity may potentially affect response and the outcome IVF treatment. The present study prospectively assessed effect a combination recFSH recLH on stimulation parameters treatment fixed multiple dose protocol.127 infertile patients with an indication for or ICSI were recruited randomized (using sealed...
At present, there are three ways to determine effectively the quality of cryopreservation procedure using ovarian tissue before re-implantation treatment: evaluation follicles after post-thawing xenotransplantation SCID mouse, in-vitro culture in a large volume medium under constant agitation and on embryonic chorio-allantoic membrane within hen's eggs. The aim this study was compare two methods, vitro chorioallantoic (CAM) cryopreserved human medulla-contained medulla-free cortex. Ovarian...
The place of GnRH antagonists in ovarian stimulation is controversial. Meta-analyses on studies comparing agonist and antagonist treatment regimens have suggested a comparatively lower efficacy antagonists, which likely to influenced clinicians' attitudes. This report describes utilization for Germany from 2000-2003. Data the national IVF registry were analysed. majority cycles are still performed long protocols, although significant increase usage has been noted (P < 0.0001). Two...
According to a representative German study prepared between 1996 and 1998 (SuSe-Study) 90% of the mothers were willing breastfeed, but only 33% (10%) babies exclusively breastfed up 4 (6) months age. Bearing in mind that period currently recommended for breastfeeding is 6 months, this discrepancy highlights need action identify causes. The present investigates behavioural pattern 4-5 after delivery.The investigation was carried out as cross-sectional who intended breastfeed their (n = 52)....
Fear of cancer treatment can become overwhelming. It is important to understand what patients are mainly afraid and factors correlated with intense fear treatment.Patients primary breast (n = 761) completed questionnaires about before surgery (t1), (t2) after (t3) adjuvant treatment. Psychological comorbidity was assessed using the Patient Health Questionnaire. Logistic regression identified predictors were most chemotherapy (mean score 3.5), remained high throughout follow-up; radiotherapy...
There is much variability and no consensus on the definition of most relevant outcome parameter after assisted reproduction technology (ART). Descriptive reports, such as annual statistics from national registries success ART programmes, should present treatment in terms live birth per ovarian stimulation started, this information for patients doctors alike. Addressing concerns about high rate multiple pregnancies, rescaling large programmes audits to singleton, birth, might trigger a global...
The results of the international St. Gallen Consensus Conference for treatment patients with primary breast cancer were discussed this year by a working group leading experts in view therapy recommendations everyday clinical practice Germany. Three are also members year's panel. comparison annually updated AGO 2019 as well S3 guideline is useful, since panel represent opinions from various countries and disciplines. based on evidence-based research literature. This 16th conference featured...