- Green IT and Sustainability
- Neuroscience and Neuropharmacology Research
- RNA and protein synthesis mechanisms
- Parallel Computing and Optimization Techniques
- Neural dynamics and brain function
- Ophthalmology and Visual Health Research
- Innovations in Medical Education
- Clinical Reasoning and Diagnostic Skills
- Neurogenetic and Muscular Disorders Research
- Embedded Systems Design Techniques
- RNA Research and Splicing
- Photoreceptor and optogenetics research
Duy Tan University
2023
Northwestern University
2023
University of California, Berkeley
2020
California State University, Sacramento
2005
Significance The prefrontal cortex (PFC) has long been recognized as a crucial region for suppressing impulsive behavior, but the specific neurons mediating effect remained elusive. Using projection-specific labeling of PFC imaging and optogenetic manipulation in mice performing go/no-go task, we showed that subset layer 5 pyramidal projecting to subthalamic nucleus, not those lateral hypothalamus or visual cortex, play critical role inhibiting responses. Our demonstration distinct...
Amyotrophic lateral sclerosis and frontotemporal dementia patients with a hexanucleotide repeat expansion in C9ORF72 (C9-HRE) accumulate poly-GR poly-PR aggregates. The pathogenicity of these arginine-rich dipeptide repeats (R-DPRs) is thought to be driven by their propensity bind low-complexity domains multivalent proteins. However, the ability R-DPRs native RNA significance this interaction remain unclear. Here, we used computational experimental approaches characterize physicochemical...
Traditionally, the effect of assessment item types including true/false questions (TFQs), multiple-choice (MCQs), short answer (SAQs), and case scenario (CSQs) is examined through psychometric qualities or student interviews. However, brain activity while answering such items remains unknown. Functional near-infrared spectroscopy (fNIRS) can be used to safely measure cerebral cortex hemodynamic response during various tasks. Hence, this fNIRS study aimed determine differences in...
A vital resource for ubiquitous computing systems is energy. Today, energy has been elevated to the status of a first class operating system resource. major challenge how manage power consumption in computer so as achieve goals performance, quality service, complexity, cost, and conservation. Power-aware involves wide range systems, from mobile embedded high-performance servers. In this paper, we describe Windows based management tool called RPM that used provide local remote systems. The...