- Air Quality Monitoring and Forecasting
- Air Quality and Health Impacts
- Vehicle emissions and performance
- Pharmacogenetics and Drug Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Drug Transport and Resistance Mechanisms
- Optical measurement and interference techniques
- 3D Surveying and Cultural Heritage
- Satellite Image Processing and Photogrammetry
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Barrier Structure and Function Studies
- Pharmaceutical studies and practices
- Estrogen and related hormone effects
- Pharmaceutical and Antibiotic Environmental Impacts
- Synthesis and Biological Evaluation
- Synthesis and Reactions of Organic Compounds
- Pregnancy and Medication Impact
- Neurological Disease Mechanisms and Treatments
Wuhan University
2022
Mudanjiang Medical University
2021
Peking University
2016-2019
State Key Joint Laboratory of Environment Simulation and Pollution Control
2016
Huazhong Agricultural University
2013-2015
Cerebral ischemia/reperfusion injury (CI/R) is associated with high mortality and remains a large challenge in the clinic. Syringin bioactive compound anti-inflammation, antioxidant, as well neuroprotective effects. Nevertheless, whether syringin could protect against CI/R its potential mechanism was still unclear.Rats were randomly divided into five groups: sham group, + LPS (TLR4 agonist) group. The rat model established by middle cerebral artery occlusion (MCAO). learning memory ability...
Aditoprim, a new bacteriostatic agent that belongs to diaminopyrimidines, has broad antimicrobial spectrum, good antibacterial activity and excellent pharmacokinetics. To evaluate the reproductive toxicity teratogenic potential of aditoprim, different concentrations aditoprim were administered Wistar rats by feeding diets containing 0, 20, 100 1000 mg kg(-1) , respectively. Each group consisting 18 males 25 females (F0 ) was treated with through 13-week period before mating during mating,...
Aditoprim (ADP), a new developed dihydrofolate reductase (DHFR) inhibitor, has great potential in clinical veterinary medicine because of its greater pharmacokinetic properties than structural analogs. Preclinical toxicology studies were performed to assess the safety ADP including an acute oral toxicity test, subchronic test and five mutagenicity tests. In was administered singly by gavage Wistar rats Kunming mice. The LD50 calculated 1400 mg kg(-1) body weight (BW) day(-1) 1130 BW study,...
Pushbroom time delay integration charge-coupled device imaging is the primary mode of high-resolution satellites. This requires an inverse transformation to determine image coordinates from ground relying on iterative algorithm. process complicated and time-consuming, convergence may fail. With improvement agility mobility optical satellites, curve scanning becomes possible, which will be dominant greatly improve observation efficiency satellite in future. However, traditional algorithm no...
Abstract. Vehicle emissions are a major source of air pollution in urban areas, and thus greatly impact quality the megacity Beijing. Various vehicle emission control policies have been implemented at great cost, but there is lack appropriate methods to evaluate effectiveness such policies. Here we developed wavelet transform method (WTM) during 2014 Asia-Pacific Economic Cooperation (APEC) summit, taking advantage high time resolution mobile measurements NO, NOx, BC, CO, SO2, O3 made around...