Derek Stewart

ORCID: 0000-0001-9838-4265
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Berry genetics and cultivation research
  • Potato Plant Research
  • Horticultural and Viticultural Research
  • Plant Physiology and Cultivation Studies
  • Lignin and Wood Chemistry
  • Antioxidant Activity and Oxidative Stress
  • Plant biochemistry and biosynthesis
  • Fermentation and Sensory Analysis
  • Biochemical and biochemical processes
  • Postharvest Quality and Shelf Life Management
  • Plant Pathogens and Resistance
  • Food composition and properties
  • Pomegranate: compositions and health benefits
  • Natural Antidiabetic Agents Studies
  • Polysaccharides and Plant Cell Walls
  • Ginkgo biloba and Cashew Applications
  • Plant Gene Expression Analysis
  • Advanced Cellulose Research Studies
  • Tea Polyphenols and Effects
  • Metabolomics and Mass Spectrometry Studies
  • Enzyme-mediated dye degradation
  • Plant Disease Resistance and Genetics
  • Genomics, phytochemicals, and oxidative stress
  • Microbial Metabolites in Food Biotechnology

James Hutton Institute
2015-2025

Ollscoil na Gaillimhe – University of Galway
2025

Heriot-Watt University
2013-2022

Universidade Nova de Lisboa
2020

Norwegian Institute of Bioeconomy Research
2015-2018

Physical Sciences (United States)
2017

Engineering and Physical Sciences Research Council
2017

Czech Agrifood Research Center
1991-2014

NILU
2014

University of Glasgow
2013

Polyphenol-rich extracts from soft fruits were tested for their ability to inhibit α-amylase and α-glucosidase. All caused some inhibition of α-amylase, but there was a 10-fold difference between the least most effective extracts. Strawberry raspberry more inhibitors than blueberry, blackcurrant, or red cabbage. Conversely, α-glucosidase readily inhibited by blueberry blackcurrant The extent related anthocyanin content. For example, extracts, which have highest content, in inhibiting...

10.1021/jf0489926 article EN Journal of Agricultural and Food Chemistry 2005-03-05

Abstract Legumes have the potential to support global protein production by partially replacing meat and dairy products in human diet. This will not only help meeting increasing worldwide demand for proteins, but could contribute towards mitigating threat imposed environment current agricultural practices higher‐economy countries (dependence on fossil fuel energy harmful emissions). Among legumes, fava bean ( Vicia faba L .) is a valuable crop. It rich source of fiber, other non‐nutrient...

10.1111/1541-4337.12146 article EN Comprehensive Reviews in Food Science and Food Safety 2015-06-23

Age-related complications such as neurodegenerative disorders are increasing and remain cureless. The possibility of altering the progression or development these multifactorial diseases through diet is an emerging attractive approach with experimental support. We examined potential known bioavailable phenolic sulfates, arising from colonic metabolism berries, to influence hallmarks processes. In silico predictions in vitro transport studies across blood-brain barrier (BBB) endothelial...

10.1038/s41598-017-11512-6 article EN cc-by Scientific Reports 2017-09-07

The bioavailability of anthocyanins from raspberry extracts was assessed using an in vitro digestion procedure that mimics the physiochemical and biochemical changes occur upper gastrointestinal tract (GIT). Effectively all total phenol content extract survived gastric partitioned between IN sample, which represents serum available material, OUT material remains GIT passes through to colon. All also digestion, but only ∼5% entered sample ∼70% were recovered samples. Codigestion with commonly...

10.1021/jf050131p article EN Journal of Agricultural and Food Chemistry 2005-07-01

A protocol is described to isolate small quantities of highly purified cellulose for isotopic analysis 10–100 mg samples secondary (Pinus sylvestris L.) and primary (Rubus idaeus plant cell wall material. Elemental 350 isolated from pine wood estimated the relative carbon content be ca. 43.7% ± 1.2%. This value indicates that quality high reproducible. High-performance anion exchange chromatography with pulsed amperometric detection hydrolysis products quantified purity as 99% cellulose....

10.1002/(sici)1099-1565(200001/02)11:1<7::aid-pca488>3.0.co;2-u article EN Phytochemical Analysis 2000-01-01

The ingestion of dietary fibre has been correlated with the prevention many health-threatening diseases and cancers. Plant cell walls are major source this review investigates relationship between structure different types plant their beneficial effects. effects processing cooking on also examined. Structure–function relationships individual wall components not well defined it may be that physical, physiochemical topochemical properties important.

10.1002/(sici)1097-0010(199602)70:2<133::aid-jsfa495>3.0.co;2-4 article EN Journal of the Science of Food and Agriculture 1996-02-01

The nature of the enzyme(s) involved in dehydrogenative polymerization lignin monomers is still a matter debate. Potential candidates include laccases which have recently received attention due to their capacity oxidize and close spatial temporal correlation with deposition. We characterized two H 2 O ‐independent phenoloxidases approximate molecular masses 90 kDa 110 from cell walls Populus euramericana xylem that are capable oxidizing coniferyl alcohol. 90‐kDa protein was purified apparent...

10.1046/j.1432-1327.1999.00061.x article EN European Journal of Biochemistry 1999-01-01

Polyphenol-rich berry extracts were screened for their antiproliferative effectiveness using human cervical cancer (HeLa) cells grown in microtiter plates. Rowan berry, raspberry, lingonberry, cloudberry, arctic bramble, and strawberry effective but blueberry, sea buckthorn, pomegranate considerably less effective. The most (strawberry > bramble cloudberry lingonberry) gave EC50 values the range of 25–40 µg/(mL phenols). These also against colon (CaCo-2) cells, which generally more sensitive...

10.1021/jf073469n article EN Journal of Agricultural and Food Chemistry 2008-04-16

Polyphenol-rich extracts from a range of berries inhibited α-amylase in vitro, but the most effective were raspberry and rowanberry (IC50 values 21.0 4.5 μg/mL, respectively). The inhibitory components examined by different approaches. Extracts yellow red raspberries equally able to inhibit α-amylase. Because effectively lacked anthocyanins, this suggested that they not crucial for amylase inhibition. Notably, however, higher levels other phenolic (particularly, ellagitannins) did increase...

10.1021/jf1045359 article EN Journal of Agricultural and Food Chemistry 2011-02-17

Benzothiadiazole (BTH) enhanced the accumulation of soluble and cell-wall-bound phenolics in strawberry leaves also improved resistance to powdery mildew infection under greenhouse conditions. The most pronounced change was seen levels ellagitannins, which increased up 2- 6-fold 4 days after BTH application, but persisted only inoculated plants. induction phenolic metabolism by reflected fruits, several compounds being inoculated, BTH-treated Basal salicylic acid (SA) content high leaves, a...

10.1021/jf063452p article EN Journal of Agricultural and Food Chemistry 2007-02-06

Many guanide-containing drugs are antihyperglycaemic but most exhibit toxicity, to the extent that only biguanide metformin has enjoyed sustained clinical use. Here, we have isolated unique mitochondrial redox control properties of likely account for this difference. In primary hepatocytes and H4IIE hepatoma cells found diguanides DG5-DG10 phenformin were up 1000-fold more potent than on cell signalling responses, gluconeogenic promoter expression hepatocyte glucose production. Each drug...

10.1016/j.redox.2017.08.018 article EN cc-by Redox Biology 2017-08-26

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRearrangement Peaks in the Mass Spectra of Certain Aliphatic AcidsG. P. Happ and D. W. StewartCite this: J. Am. Chem. Soc. 1952, 74, 17, 4404–4408Publication Date (Print):September 1, 1952Publication History Published online1 May 2002Published inissue 1 September 1952https://doi.org/10.1021/ja01137a050RIGHTS & PERMISSIONSArticle Views126Altmetric-Citations77LEARN ABOUT THESE METRICSArticle Views are COUNTER-compliant sum full text article downloads...

10.1021/ja01137a050 article EN Journal of the American Chemical Society 1952-09-01

Abstract Fibres from plant sources have been used by man for many generations and there is increasing interest in the potential use of such fibres non‐tree various applications. This review brings together most relevant literature on botany, chemistry processing. The different cell types are explained those which produce highlighted conjunction with actual plants involved. wall addressed special consideration to components fibre walls biosynthesis, where known, explained. Finally, methods...

10.1002/jsfa.2740620102 article EN Journal of the Science of Food and Agriculture 1993-01-01
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