A5050107922- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Minimally Invasive Surgical Techniques
- Gastrointestinal Tumor Research and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Diverticular Disease and Complications
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Surgical Simulation and Training
- Radiomics and Machine Learning in Medical Imaging
- Circular RNAs in diseases
- Anorectal Disease Treatments and Outcomes
- Nutrition and Health in Aging
- Gastrointestinal disorders and treatments
- Enhanced Recovery After Surgery
- Inflammatory Bowel Disease
- Curcumin's Biomedical Applications
- Intestinal Malrotation and Obstruction Disorders
- Tattoo and Body Piercing Complications
- Gastroesophageal reflux and treatments
- Abdominal Surgery and Complications
- Lung Cancer Diagnosis and Treatment
Ewha Womans University
2012-2025
Ewha Womans University Medical Center
2020-2023
Hallym University Sacred Heart Hospital
2023
Intuitive Surgical (United States)
2021
Intuit (United States)
2021
Yonsei University
2016-2020
Severance Hospital
2016-2017
Asan Medical Center
2014
Colorectal cancer is the third most common in Korea and leading cause of death from cancer. Treatment outcomes for colon are steadily improving due to national health screening programs with advances diagnostic methods, surgical techniques, therapeutic agents.. The Colon Cancer Multidisciplinary (KCCM) Committee intends provide professionals who treat up-to-date, evidence-based practice guidelines improve help them make decisions that reflect their patients' values preferences. These have...
Abstract Background Recent studies have emphasized the role of mesenteric changes, including creeping fat, alongside intestinal alterations in progression Crohn's disease (CD). This study aims to investigate fibrosis and changes using tissues obtained from CD patients who underwent surgery for complications such as strictures perforations. Methods From September 2023 2024, (CD-Inflamed-Bowel/CD-Uninflamed-Bowel) (CD-Inflamed-Mes/CD-Uninflamed-Mes/ CD-Uninvolved-Mes) were collected nine...
<h3>Introduction</h3> Postoperative delirium is one of the most common complications major surgery, affecting 10–70% surgical patients 60 years and older. Delirium an acute change in cognition that manifests as poor attention illogical thinking associated with longer intensive care unit (ICU) hospital stay, long-lasting cognitive deterioration increased mortality. Ketamine has been used anaesthetic drug for over 50 established safety record. Recent research suggests that, addition to...
Anastomotic leakage (AL) is a well-known cause of morbidity after low anterior resection (LAR) for rectal cancer, but its impact on oncologic outcome not well understood. The aim this study to investigate the AL long-term and identify factors associated with that may affect prognosis LAR cancer. A retrospective analysis patients who underwent curative cancer without diverting stoma was performed. To related be outcome, Clavien-Dindo grades, prognostic nutritional indices (PNI) inflammatory...
Abstract Background The da Vinci Surgical System (Intuitive Surgical, Sunnyvale, CA) was introduced to overcome the limitations of single‐incision laparoscopic surgery, which is challenging due its restrictions regarding triangulation and retraction. purpose this article describe initial experience with surgery using Vinvci Single‐Port Platform (dVSP). Methods medical records patients colorectal disease, who underwent robotic dVSP, were retrospectively reviewed. Results Five appendiceal...
The aim of this study is to investigate if retrieval 12 lymph nodes (LNs) sufficient avoid stage migration as well evaluate the prognostic impact insufficient LN in different treatment settings rectal cancer, particularly case preoperative chemoradiotherapy (pCRT). data all patients with biopsy proven adenocarcinoma who underwent curative surgery between January 2005 and December 2012 were analyzed. Univariate multivariate analyses for oncologic outcomes performed metastasis or no (LN−)...
Cancer-cell-derived exosomes confer oncogenic properties in their tumor microenvironment and to other cells; however, the exact mechanism underlying this process is unclear. Here, we investigated roles of cancer-cell-derived colon cancer. Exosomes were isolated from cancer cell lines, HT-29, SW480, LoVo, using an ExoQuick-TC kit, identified Western blotting for exosome markers, characterized transmission electron microscopy nanosight tracking analysis. The used treat HT-29 evaluate effect on...
Purpose Adjuvant chemotherapy is routinely recommended for locally advanced colorectal cancer (CRC). There are very few data the optimal starting date of adjuvant after surgery. This study aimed to evaluate effectiveness earlier adoption curative surgery stage III CRC. Methods In this study, 159 patients with CRC, who had undergone a resection, were enrolled retrospectively. Patients categorized into 3 groups representing different timings initiate chemotherapy; less than 2 weeks (group 1),...
Exosomes are a group of small membranous vesicles that shed into the extracellular environment by tumoral or non-tumoral cells and contribute to cellular communication delivering micro RNAs (miRNAs). In this study, we aimed evaluate role exosomal miRNAs from colorectal cancer cell lines in tumorigenesis, affecting cancer-associated fibroblasts (CAFs), which vital constituents tumor microenvironment. To analyze effect miRNA on microenvironment, migration monocytic line THP-1 was evaluated via...
There has been little enthusiasm for performing robotic colectomy colon cancer in recent years due to multiple factors, one being that the previous systems such as da Vinci Si® (dVSi) were poorly designed multi-quadrant surgery. The new Xi® (dVXi) system enables with central mesocolic excision be performed easily a single docking procedure. We developed universal port placement strategy allow right and left hemicolectomies via suprapubic approach Pfannensteil extraction site. This proof of...
Tumors at the level of anorectal junction had required total levator-ani muscle excision to achieve an adequate resection margin. However, in cases tumor invading ipsilateral and intact external sphincter, en bloc rectum with including would be possible. This hemilevator (HLE) technique enables preserving anal sphincter function while obtaining oncologic clearance avoiding permanent colostomy those patients. study aimed evaluate surgical outcomes feasibility HLE.Data on 13 consecutive...
Background: This study aimed to establish a threshold of C-reactive protein (CRP) level for early detection post-operative infectious complications after surgery colorectal cancer. Patients and Methods: In this single-center, retrospective analysis, we studied the data 178 patients who underwent cancer between January 2018 February 2022. Elective with curative intent was performed, serum CRP levels were measured on five consecutive days surgery. Receiver operating characteristic curves...
Curcumin has attracted attention for its nontoxic chemopreventive effects; however, the specific pathways underlying anticancer effects in colon cancer remain unclear. This study investigated potential interplay between curcumin and integrin β1 cancer. HCT116 fibroblast cells were treated with curcumin, cell proliferation was assessed using MTT assay western blotting. We analyzed expression after treatment of blotting confocal microscopy. The roles talin rab25 activation by same methods....
Objectives: Interest in the association between particulate air pollution and appendicitis risk has been increasing recent years, previous studies have suggested a link matter ≤10 μm diameter (PM10) appendicitis. However, robust evidence is currently lacking. This study explored short-term PM10 exposure using data from Ewha Womans University Mokdong Hospital, Seoul, Korea, January 1, 2001 December 31, 2018. Methods: We employed time-stratified case-crossover design 6,526 patients taken...
Purposes Although adjuvant chemotherapy (AC) has been established as a standard of treatment for advanced rectal cancer, there is no guideline regarding the timing AC initiation. In this study, we aimed to evaluate oncologic outcome early initiation and clarify ideal time among cancer patients receiving preoperative chemo-radiotherapy (preCRT). Methods The medical records 719 who underwent curative resection followed by were analyzed retrospectively. Data distributions compared according...
Narrow pelvis has been considered an adverse factor for postoperative and oncologic outcomes after rectal cancer surgery. The aim of this study was to investigate the validity using only axial CT scan images calculate pelvic cross-sectional area prediction surgery.The medical records patients who underwent surgery were reviewed analyzed retrospectively. Axial used measure area. Pelvic surgical site infection (SSI), positive resection margin, early local recurrence adopted as end-points...
Abstract Background This study aimed to evaluate transabdominal single‐incision robotic surgery using the da Vinci SP (dVSP, Intuitive Surgical, Sunnyvale, CA, USA) surgical system for retrorectal tumours. Methods Eight patients who underwent excision of tumours dVSP were retrospectively analysed. Results Five (62.5%) had positioned above levator ani muscle, two (25.0%) that extending across and one (12.5%) located below muscle. All procedures successfully completed without any...
Purpose: Blood transfusion is one of the most common procedures used to treat anemia in colorectal surgery. Despite controversy regarding adverse effects blood products, surgeons have maintained standards for administering transfusions. However, this trend was restrictive during COVID-19 pandemic because a shortage products. In study, we conducted an analysis investigate whether restriction transfusions affected postoperative surgical outcomes.Methods: Medical records 318 patients who...
Alcohol is well-recognized systemic toxin that causes numerous adverse effects, including psychosocial problems, fatal myocardial infarction, stroke and atherosclerosis. The intra-abdominal complications caused by acute alcohol consumption have not been defined. We report an 80-year-old man with sub-acute small bowel colonic ischemia after heavy intake in one sitting. performed a resection of gangrenous segments. Microscopically, there were diffuse vasoconstriction the mesenteric vessels...