A5012386698- Systemic Lupus Erythematosus Research
- Spondyloarthritis Studies and Treatments
- Peripheral Neuropathies and Disorders
- MicroRNA in disease regulation
- Lymphoma Diagnosis and Treatment
- Rheumatoid Arthritis Research and Therapies
- Peptidase Inhibition and Analysis
- Pharmacological Effects of Natural Compounds
- Pharmacological Effects and Toxicity Studies
- Acute Myeloid Leukemia Research
- Viral-associated cancers and disorders
- Complement system in diseases
- Thyroid Cancer Diagnosis and Treatment
- Immune cells in cancer
- SARS-CoV-2 and COVID-19 Research
- Vitamin D Research Studies
- Chronic Lymphocytic Leukemia Research
- Extracellular vesicles in disease
- Cancer Mechanisms and Therapy
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- COVID-19 Clinical Research Studies
- Cardiac Imaging and Diagnostics
- Intraperitoneal and Appendiceal Malignancies
- PI3K/AKT/mTOR signaling in cancer
Tabriz University of Medical Sciences
2020-2025
Emory University
2025
Tissue Gene (United States)
2023
Cardiac fibrosis is a pivotal cardiovascular disease (CVD) process and represents notable health concern worldwide. While the complex mechanisms underlying CVD have been widely investigated, recent research has highlighted microRNA-21’s (miR-21) role in cardiac pathogenesis. In this narrative review, we explore molecular interactions, focusing on of miR-21 contributing to fibrosis. Various signaling pathways, such as RAAS, TGF-β, IL-6, IL-1, ERK, PI3K-Akt, PTEN besides dysregulation...
Background: The current advances in radiotherapy (RT) have improved the outcome of breast cancer (BC) patients. Despite its therapeutic benefits, iatrogenic toxicities RT and impact on BC survivors are still debated, further evaluations should be considered. This study aims to assess rate subclinical hypothyroidism hypoparathyroidism among patients who were exposed radiation. Methods: Seventy females undergoing for enrolled this cross-sectional study. Laboratory assessment thyroid...
This study investigated the correlation between PD-L1 expression, metastasis, and survival in colorectal cancer (CRC) patients. expression was not significantly associated with overall survival, disease-free or mortality rate. However, a significant difference observed positive negative patients regarding presence of which higher group. These findings suggest that may impact metastasis CRC but survival.
Abstract: Triple-negative breast cancer (TNBC) presents considerable obstacles because of its highly aggressive characteristics and limited availability specific therapeutic interventions. The utilization monoclonal antibody (mAb)-based immunotherapy is a viable approach to tackle these difficulties. This review aims examine the present state mAb-based in TNBC, focusing on underlying mechanisms action, clinical applications, existing challenges. effectiveness mAbs reducing tumor development,...
Novel and rare chromosomal aberrations in AML are important to understand, particularly if associated with tumorigenesis how they contribute prognostic risk. It is that acute leukemia be treated right away. Herein, novel (x; 3) (q24; p13) described.
The rare co-occurrence of takayasu arteritis (TAK) and ulcerative colitis (UC), presenting with asymptomatic onset neurological complications, highlights the importance an integrated diagnostic approach for overlapping autoimmune conditions.
Key Clinical Message Infectious diseases like leprosy can cause antiphospholipid antibodies, leading to blood clots. Clinicians should consider this for patients with unusual thrombotic events and prior infectious disease history. Abstract This case report details the diagnostic challenge of a 42‐year‐old man history treated who presented clinical features suggestive syndrome (APS). Vascular angiography revealed thrombosis, serological tests were positive APS antibodies. However, patient...
Background This study investigated the association between prostaglandins, vitamin D levels, and their potential role in acute myeloid leukemia (AML). Previous research has shown prostaglandins' stimulatory effects D's inhibitory various malignancies. Methods cross-sectional evaluated 54 AML patients at Shahid Ghazi Center of Imam Reza Hospital Tabriz. Prostaglandin E2 (PGE2), Cyclooxygenase-2 (COX-2), serum as well gene expression 5-hydroxyprostaglandin dehydrogenase (15-PGDH), COX-2, PGE2...
Key Clinical Message The association of familial Mediterranean fever and ankylosing spondylitis is rare, but it essential to consider this diagnosis in patients with a history FMF who develop symptoms back pain or other rheumatologic conditions. Abstract Familial (FMF) an inherited inflammatory disorder characterized by recurrent episodes, abdominal pain, arthralgia. Ankylosing (AS) chronic disease that affects the spine's joints. AS rare. We report case 22‐year‐old male patient positive...
Background Glucagon-like peptide-1 (GLP-1), a gut-derived incretin hormone, plays pivotal role in glucose-induced insulin secretion. Currently, the of hormones pathogenesis cirrhosis is not clearly defined. This study aimed to investigate circulating levels GLP-1 liver and its association with severity disease.Methods A total 80 participants including 39 patients definite diagnosis 41 healthy controls recruited this cross-sectional study. Circulating were determined using ELISA method. The...