A5079855268- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Vascular anomalies and interventions
- Cardiovascular Function and Risk Factors
- Central Venous Catheters and Hemodialysis
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Muscle and Compartmental Disorders
- Aortic Disease and Treatment Approaches
- Hemodynamic Monitoring and Therapy
- Sports injuries and prevention
- Dialysis and Renal Disease Management
- Diabetic Foot Ulcer Assessment and Management
- Blood Coagulation and Thrombosis Mechanisms
- Acute Ischemic Stroke Management
- Effects of Radiation Exposure
- Cardiovascular Effects of Exercise
- Thermoregulation and physiological responses
- Shoulder Injury and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Lung Cancer Diagnosis and Treatment
Karolinska Institutet
2009-2022
St Göran's Children's Hospital
1988-2020
Stockholm South General Hospital
2005-2017
Stockholm Environment Institute
2011
Karolinska University Hospital
1997-1999
Saint Göran Hospital
1994
Objectives: Prophylaxis against thromboembolic complications has become routine after major orthopedic surgery. In contrast, it remains an issue for debate whether prophylaxis minor surgery and immobilization is necessary, even though these treatments are well-known risk factors deep-vein thrombosis (DVT). The objective of this study was to evaluate the efficacy dalteparin during lower-limb surgical treatment Achilles tendon rupture. Design Setting, Patients: Randomized, placebo-controlled,...
Background and Purpose —An increase in intima-media thickness (IMT) the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose this study was to investigate relationship between IMT CCA atherosclerosis bifurcation. Methods —182 consecutive patients (mean age, 67 years) referred for duplex scanning were included. We measured classified plaques by means high-resolution ultrasound technique. Results —IMT correlated male gender, ischemic heart disease, presence...
Skeletal trauma and immobilization are well-known risk factors for deep vein thrombosis (DVT) pulmonary embolism (PE). While prophylaxis against thromboembolic complications has become routine after major orthopedic surgery, whether or not minor surgery lower limb is necessary still under debate.In a double-blind, placebo-controlled study, 272 consecutive patients were randomized to receive either thromboprophylaxis with Dalteparin (n = 136) placebo 5 weeks ankle fracture surgery. All...
Environmental exposures filtered through the genetic make-up of each individual alter transcriptional repertoire in organs central to metabolic homeostasis, thereby affecting arterial lipid accumulation, inflammation, and development coronary artery disease (CAD). The primary aim Stockholm Atherosclerosis Gene Expression (STAGE) study was determine whether there are functionally associated genes (rather than genes) important for CAD development. To this end, two-way clustering used on 278...
Patients with type 1 diabetes have a substantial risk of developing cardiovascular complications early in life. We aimed to explore the role insulin sensitivity (Si) as an factor atherosclerosis young vs. non-diabetic subjects. Forty adolescent and adult individuals (20 diabetics 20 non-diabetics), age 14–20 years, without characteristics metabolic syndrome, participated this cross-sectional study. After overnight fast, Si was measured by hyperinsulinemic euglycemic clamp (40 mU/m2)...
Increased intima-media thickness (IMT) in the common carotid artery (CCA) correlates with conventional risk factors for cardiovascular disease and is an independent predictor of cardiac events. However, correlation between IMT degree ischemic heart evaluated by coronary angiogram weak. The purpose this study was to investigate relationship measures atherosclerosis extent severity (CAD) 111 consecutive patients (60 men 51 women, mean age 60 years) known or suspected CAD who were investigated...
We aimed to establish reference values for three important properties of the arterial wall using a conventional ultrasound scanner. measured: (1) intima-media thickness (IMT) carotid arteries with internal trace function system; (2) stiffness by pulsatile diameter changes in right common artery assessed M-mode; and (3) endothelial expressed as flow-mediated dilatation (FMD) brachial artery. IMT measurements reproducibility were compared those obtained external analysing systems. All...
Twenty-five elderly patients with peripheral vascular disease and intermittent claudication were prospectively followed during a six-month session of physical training. Neuroendocrine metabolic patterns as well effects on walking performance assessed the training period. At initial evaluation there was an inverse association between distance serum cortisol blood glucose levels. The increased A positive effect homeostatis seen decreased basal fructosamine levels after During exercise decrease...
Hemodynamic and endocrine variables have been unsuccessful to predict improvement in walking distance patients with intermittent claudication following structured training programs. In the present study we evaluated predictive value of a number hemodynamic parameters. addition included information on cognitive factors such as stress belief motivation participate. Twenty-five elderly subjects were studied. Significant overall was achieved. The most important explanatory relative training,...
Background The stability of atherosclerotic plaques determines the risk for rupture, which may lead to thrombus formation and potentially severe clinical complications such as myocardial infarction stroke. Although rate plaque be important stability, this process is not well understood. We took advantage atmospheric 14C-declination curve (a result atomic bomb tests in 1950s 1960s) determine average biological age carotid plaques. Methodology/Principal Finding cores were dissected from 29...
In this prospective study duplex scanning was performed in 21 consecutive patients (23 lower extremities) referred for descending phlebography. The grade of deep venous insufficiency (Grades 1-4) estimated a blinded fashion with phlebography and technique. Agreement occurred 15 23 extremities. Discrepancies were found particularly minor degrees reflux. reflux below the knee according to also identified ultrasonography. authors be an accurate method evaluating valvular function. With...