A5029520268- Healthcare Systems and Public Health
- Cardiac Health and Mental Health
- Medication Adherence and Compliance
- Acute Myocardial Infarction Research
- Pharmaceutical Practices and Patient Outcomes
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Lipoproteins and Cardiovascular Health
- Lysosomal Storage Disorders Research
- Trypanosoma species research and implications
- Health Sciences Research and Education
- Artificial Intelligence in Healthcare and Education
- Glycosylation and Glycoproteins Research
- Helicobacter pylori-related gastroenterology studies
- Blood Pressure and Hypertension Studies
- Diabetes Management and Education
- Global Public Health Policies and Epidemiology
- Health and Wellbeing Research
- Mobile Health and mHealth Applications
- Gastrointestinal motility and disorders
- Social Media in Health Education
- Microscopic Colitis
- Antiplatelet Therapy and Cardiovascular Diseases
Peoples' Friendship University of Russia
2006-2025
Russian New University
2017
Adherence is one of the crucial determinants high-quality and effective pharmacotherapy. Along with search for optimal methods to improve adherence study factors influencing it, it remains an equally urgent task choose method evaluate it. In context digitalization healthcare systems that actively taking place in many countries, including Russia, approach based on analysis prescription data greatest interest among all known measuring adherence. The calculation «proportion days covered» (PDC)...
The paper deals with the problem of interchangeability brand-name and generic drugs. Touching upon official terminology normative documents that govern registration generics in Russia foreign countries, authors state there is no concerted approach to estimating drug interchangeability, indicate are some disadvantages using a method for proving bioequivalence compared drugs as evidence their therapeutic equivalence, point out Russia's legal regulation circulation lacks attention proper use...
Background. Currently, the main treatment for Gaucher disease is enzyme replacement therapy. Recombinant glucocerebrosidase (imiglu-cerase) first biotechnological drug therapy with proven clinical efficacy and safety of patients different ages type 1 3, used in practice since 1994. In Russia, within framework "Pharma 2020" pharmaceutical industry development strategy, biosimilar imiglucerase, Glurazyme®, was developed. The obtained results preclinical studies became basis a phase I...
Aim. To study medication adherence in elderly patients with coronary artery disease (CAD) primary care practice. Material and methods . The conducted out-patient clinic of Moscow city. 293 (≥65 years) established CAD included. following patient data obtained via electronic medical record system: demography, history, modifiable risk factors prescribed pharmacotherapy. Level measured by Morisky scale (MMAS-8) telephone survey. Results. According to high was identified 146 (49.8%) patients,...
Aim. To study secondary prevention of cardiovascular diseases among patients different age groups with a history myocardial infarction by the example outpatient cardiology institution. Material and methods . Retrospective pharmacoepidemiological was conducted analyzing medical records 825 infarction, who visited institution for first time in 2011. Patients were divided into two according to their age: younger than 60 years (n=308), older (n=517). Results. The population elderly more severe:...
Aim . To analyze changes in the pattern of lipid-lowering therapy (LLT) outpatients with stable coronary artery disease (SCAD) over 7-year period. Material and methods This pharmacoepidemiological, retrospective, cross-sectional, two-stage study was conducted on basis primary care facility Moscow. We analyzed 1,834 805 medical records patients SCAD at first (2011) second (2018) stages, respectively. Data demography, history, lipid profile, administrated LLT were collected. Statistical...
Aim. To assess five-year trend in terms of specialists’ adherence to guidelines on secondary prevention cardiovascular diseases patients with stable angina the level out-patient specialized healthcare institution Moscow. Material and methods. Two-stage retrospective pharmacoepidemiological study was conducted. The object – patient medical records. At first stage records 2915 visited for time 2006 were included, at second 1633 primary visit 2011. Results. Over period prescription rates drugs...
Aim. To assess 5 years trend in level of doctor’s adherence to actual guidelines on secondary prevention cardiovascular diseases patients with a history myocardial infarction ambulatory specialized healthcare institution Moscow. Material and methods. There were 752 firstly visited 2006 825 – 2011. Their data was included two-stage retrospective pharmacoepidemiology study. Results. Prescription rate significantly increased for three four prophylactic groups recommended (antiplatelets 91.76%,...
Introduction: Ischemic heart disease (IHD) remains the leading cause of death both in Europe and Russia. The most common form IHD is stable angina. There compelling evidence that strict adherence to clinical guidelines greatly contributes mortality reduction. However, gap between modern knowledge use guideline-recommended medications significant. As shown by Western practice, one possible solutions this problem regular conduction pharmacoepidemiological studies.
 Objective: Investigate...