A5073948687- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Head and Neck Cancer Studies
- Congenital Diaphragmatic Hernia Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Colorectal Cancer Treatments and Studies
- COVID-19 and healthcare impacts
- RNA modifications and cancer
- Cancer Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Esophageal and GI Pathology
- Ultrasound in Clinical Applications
- Soft tissue tumor case studies
- Myasthenia Gravis and Thymoma
- Vascular Anomalies and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Uterine Myomas and Treatments
- Amoebic Infections and Treatments
Guy's and St Thomas' NHS Foundation Trust
2012-2024
Guy's Hospital
1967-2023
St Thomas' Hospital
2012-2021
Wythenshawe Hospital
2006-2021
St. Thomas Hospital
2015
Bristol-Myers Squibb (Switzerland)
2012
Cancer Clinic
2010
Heartlands Hospital
2005
University of Manchester
2001
Abstract Aim We wanted to examine survival in patients with resected colorectal cancer (CRC) whose lung metastases are or not resected. Methods Teams participating the study of Pulmonary Metastasectomy Colorectal Cancer (PulMiCC) identified potential candidates for metastasectomy and invited their consent join Stage 1. Baseline data related CRC fitness surgery were collected. Eligible randomization PulMiCC randomized controlled trial (Stage 2). Sites provided case report forms non‐randomized...
Postoperative atrial fibrillation (POAF) increases morbidity, hospital stay and healthcare expenditure. This study aims to determine the perioperative factors correlating with POAF as well evaluate both treatment strategies AF persistence beyond discharge.The records of all patients undergoing anatomical lung resection over a 1-year period were retrospectively reviewed. Patients history arrhythmia excluded. was defined by clinical diagnosis electrocardiography. Pre- postoperative demographic...
This study aimed to assess the efficacy of thoracotomy and decortication (T/D) in achieving lung re-expansion patients with Stage III empyema impact culture-positive on outcome decortication.This is a retrospective observational consecutive treated T/D over 6-year period.A total 107 were identified. The median age was 55 (range 16-86) years; which, 86% male. length hospital stay 9 2-45) days. Full achieved cases. There no postoperative deaths. Pleural cultures positive 56 (52%) Patients had...
Primary Mycobacterial infection of the sternum is an exceedingly rare occurrence. We present a case tuberculous osteomyelitis successfully treated with surgical debridement and vacuum-assisted closure therapy.
Post-operative quality of life (QOL) has become crucial in choosing operative approaches thoracic surgery. However, compared to VATS and thoracotomy, QOL results post-RATS are limited. We before after RATS between RATS, VATS, thoracotomy. conducted a retrospective review lung cancer surgical patients from 2015 2020. Patients completed validated EORTC questionnaires (QLQ-C30 QLQ-LC13). Results were analysed using the Scoring Guide, with statistical analysis. A total 47 (94%) pre- returned....
Abstract Aim The aim of this work was to examine the burden further treatments in patients with colorectal cancer following a decision about lung metastasectomy. Method Five teams participating Pulmonary Metastasectomy Colorectal Cancer (PulMiCC) study provided details on subsequent local for metastases, including use chemotherapy. For three groups (no metastasectomy, one metastasectomy or multiple interventions), baseline factors and selection criteria additional were examined. Results five...
The aim of this retrospective study is to investigate the immediate and long-term outcomes following insertion covered uncovered self-expandable metallic stent (SEMS) for management malignant tracheobronchial disease. A total 49 patients (27 male, mean age 60.9 ± 15 years) underwent 77 SEMS insertions (57 uncovered). procedure was performed in theater using combined bronchoscopic fluoroscopic guidance. study’s primary end points included technical success (97.9%), clinical (91.8%), symptom...
Surgeons will face an increasing number of octogenarians with lung cancer potentially curable by surgery. The goal this study was to evaluate short- and long-term outcomes after resection.We performed a single-centre consecutive patients ≥80 years old, surgically treated for suspected between 2009 2016. Age, sex, performance status, function, surgical approach, type resection, complications, in-hospital 30- 90-day deaths survival were analysed.Two hundred fifty-seven enrolled. median age 82...
Interrupted inferior vena cava (IVC) is a rare developmental defect characterised by azygos continuation following failure of fusion one or more the component parts embryological IVC and occurring in approximately 5000 general population. It usually an isolated finding generally asymptomatic. We present case non-small cell lung cancer requiring right pneumonectomy patient with interrupted continuation.
Masaoka-Koga staging system remains the most frequently applied clinical for thymic malignancy. However, International Association Study of Lung Cancer (IASLC)/International Thymic Malignancy Interest Group (ITMIG) proposed a tumor-node-metastasis (TNM) in 2014. This study aims to evaluate its impact on stage distribution, implementation, and prognosis thymomas.We performed single institution, retrospective analysis 245 consecutive patients who underwent surgical resection thymoma. 9 with...
SUMMARY An instrument and technique are described for determining MCV, MCD D/T from the visual measurement of diffraction rings produced by red cells; MCV unfixed spherical cells fixed discoidal cells. The method eliminates a serious error due to asymmetry in retinal sensitivity near fovea. accuracy measurements is assessed repeatability observations individual observers, agreement between those different observers. validity optical theory deduction cell dimensions confirmed case cells: (1)...
A 70-year-old woman presented with a 2-year history of increasing breathlessness. Computed tomography (CT) the chest confirmed well-defined cystic lesion abutting mediastinum in right hemi thorax measuring 8 × 6 cm. She underwent thoracotomy to excise lesion. Biopsies for histology demonstrated metastatic serous ovarian epithelial carcinoma. We report very unusual primary presentation carcinoma as single mediastinal mass. also include brief review literature.
Abstract Introduction Type B1 and B2 thymomas are lymphocyte-rich malignant tumors with few somatic mutations in protein-coding regions of the nuclear genome; nonetheless, non-coding remain uncharacterized. Here, we developed a rigorous tumor isolation method from thymoma tissues identified mitochondrial DNA. Methods CD205 + CD45 - pure cells were isolated fresh-frozen using DEPArray system. Deep whole-genome sequencing was performed, recurrent alterations coding, non-coding, mitochondria...
Abstract Introduction Respiratory failure has historically been the major cause of mortality after elective lung resections. With improved intubation using fiber-optic scopes, better preoperative respiratory risk assessment, more advanced anesthetic single ventilation, and minimally invasive surgical technique, this may have changed. Our objective was to assess main causes over past 10 years in patients undergoing surgery a UK center. Materials Methods A retrospective unit data search made...