A5061605906- Hydraulic Fracturing and Reservoir Analysis
- Enhanced Oil Recovery Techniques
- Drilling and Well Engineering
- Hydrocarbon exploration and reservoir analysis
- Petroleum Processing and Analysis
- Groundwater flow and contamination studies
- Reservoir Engineering and Simulation Methods
- Optical Polarization and Ellipsometry
- Seismic Imaging and Inversion Techniques
- Electromagnetic Scattering and Analysis
- Oil and Gas Production Techniques
- Colorectal Cancer Treatments and Studies
- Thyroid Cancer Diagnosis and Treatment
- Applied Advanced Technologies
- Tunneling and Rock Mechanics
- Architecture and Cultural Influences
- Optical Coatings and Gratings
- Electronic and Structural Properties of Oxides
- Rock Mechanics and Modeling
- Facilities and Workplace Management
- Smart Materials for Construction
- CO2 Sequestration and Geologic Interactions
- Glutathione Transferases and Polymorphisms
- ZnO doping and properties
- Thyroid Disorders and Treatments
China University of Petroleum, Beijing
2022-2025
Fujian Medical University
2019-2024
Fudan University Shanghai Cancer Center
2023
Wuhan University
2006
Tumor genetic testing is indispensable in the management of primary and metastatic colorectal cancer (CRC), yet indications for genomics-guided precision medicine immunotherapy must be better understood defined.We prospectively sequenced tumors from 869 Chinese patients with CRC by a large panel evaluated clinical significance single-gene somatic mutations co-occurring events CRC, as well their functional effects tumorigenic mechanisms. We systematically assessed heterogeneity tumor immune...
Natural fractures (NFs) are common in shale and tight reservoirs, where staged multi-cluster fracturing of horizontal wells is a prevalent technique for reservoir stimulation. While NFs stress interference recognized as significant factors affecting hydraulic fracture (HF) propagation, the combined influence these remains poorly understood. To address this knowledge gap, novel coupled hydro-mechanical-damage (HMD) model based on phase field method was developed to investigate propagation HFs...
Temporary plugging and diverting fracturing (TPDF) technology constitutes a pivotal stimulation methodology in the advancement of unconventional resources, given its efficacy establishing communication with natural fractures (NFs). Presently, comprehension TPDF is primarily confined to laboratory-scale experiments, notable dearth accurate knowledge regarding law geometric characteristics at field scale. This study introduces hydro-mechanical-damage model for hydraulic fracture (HF)...
Summary Particle swarm optimization (PSO) has been widely developed and applied as one of the important algorithms for problems because its few control parameters low complexity. However, conventional PSO problem premature convergence. Most optimized are adjusted manually, technology adaptive adjustment based on reinforcement learning (RL) is still immature. Therefore, this study proposes a new genetic (GAPSO) with policy gradient (PGGAPSO). The algorithm constructs strategy neural network...
The success of viscoelastic-surfactant (VES) acid in heterogeneous carbonate reservoirs depends on the wormholes propagation and diverting performance acid. However, with continuous high-permeability zone, highly viscous spent enters low-permeability zone under pressure difference, thus affecting which has been neglected recent studies. Therefore, this paper, rheological model is modified by considering velocity VES viscosity increase, a two-scale was established. Based model, process...
Uniform acid distribution is a critical challenge and key factor for the successful acidizing of carbonate reservoirs. Previous experimental studies have shown that nanoparticles can enhance viscosity thermal resistance viscoelastic surfactant (VES) fracturing fluids. However, there has been limited research on effects wormhole propagation diversion performance VES acid. This paper establishes nanoparticle rheological model based rheology experiments, introduces porous medium temperature...
Since hydraulic fracturing became widely adopted and commercialized, most studies on proppant transport have focused conventional-sized proppants (CPs) (20/40-mesh, 40/70-mesh, 70/140-mesh) in fracture models. To support branch fractures micro-fractures, micro-proppants (MPs) larger than 100 mesh been introduced. However, the mechanisms for with different particle diameters are not yet well understood. In this study, a visual flat panel model was employed to investigate MP natural under...
Sequential injection acidizing is usually applied for acid diversion and, in recent years, achieving deep penetration high-temperature reservoirs. However, there limited research on the impact of this technique wormholing. Building a successful application 180 °C carbonate formation, study investigates its underlying mechanisms, particularly wormhole development. The current employs an integrated experimental approach, combining fluid performance evaluation and selection, core flooding...
With little to no natural fracture development and the high calcite content in porous carbonate reservoirs, for multistage acid fracturing, different fluids are used form a viscous fingering fracture, thus enhancing degree of nonuniform etching. However, existing studies on fracturing mainly focused combination fluid acid, which is less specific rocks. Here, rheological properties five fluids, including guar-based fluid, cross-linked guar, gelled diverting were studied at each temperature...
Matrix acidification is one of the most effective stimulations to dissolve scales and remove damage in carbonate reservoirs. However, existing acid systems are difficult organic inorganic simultaneously, complex multi-stage alternative injection often introduces new precipitation damages reservoir. Here, based on retardation ability emulsified stable structure microemulsion, an oil-phase solvent was preferably selected, surfactant cosurfactant were optimized prepare acid-in-oil type...
Hydraulic fracturing is an important measurement for the stimulation of oil and gas wells widely used in development low-permeability ultra-low-permeability reservoirs. However, fractures can pass through barriers with poor properties during fracturing, resulting that do not reach pre-designed length. In a worse situation, it possible to communicate water layer cause sudden flooding, failure construction. order improve efficiency construction, effective way control height by laying diverting...
During horizontal well multi-stage fracturing (HWMF), superfractures are often identified. To promote the uniform propagation of multiple fractures, it is necessary to finely optimize perforation cluster locations based on geological and engineering parameters. This work proposes an efficient method design in consideration geoengineering sweet spots with similar mechanical properties. Well log data precise fiber optics (FO) monitoring results combined find main influencing factors. The...
Uniform acidizing has been an urgent challenge in strongly heterogeneous and high-temperature carbonate reservoirs. Nanoparticles have shown to enhance the viscosity of viscoelastic-surfactant (VES) fracturing fluids, thereby improving proppant carrying capacity fluid. However, there is almost no understanding nanoparticles on wormhole propagation diversion VES acid at low pH values high salinity. Here, rheological adsorption model are established based experimental results, multi-field...
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Aiming at the leakage problem in compact sandstone drilling of Keziluoyi Formation Southwest Tarim, Nano-core-emulsion was prepared by coating modified nano-SiO2 with nano-emulsion, its particle size D50 is about 100 nm, good dispersion stability. When 0.8% added to 5% bentonite slurry, fluid loss can be reduced 40%, and filter cake thickness 84%. Using a optimize plugging performance potassium polysulfonate reduce 52%, resulting dense tough, 40%. pressure conduction method evaluate rate,...