Tim Ausbüttel

ORCID: 0000-0002-0122-8758
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About
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Research Areas
  • Phytochemistry and Biological Activities
  • Phytochemistry and Bioactive Compounds
  • Plant-derived Lignans Synthesis and Bioactivity
  • Natural product bioactivities and synthesis
  • Traditional and Medicinal Uses of Annonaceae

Semmelweis University
2021-2023

Eötvös Loránd University
2021-2023

Diphyllin (1) and justicidin B (2) are arylnaphthalene lignans with antiviral antiproliferative effects. Compound 1 is also known as an effective inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). To evaluate in vitro cytotoxic potency both SARS-CoV-2 -infected cells various cancer cell lines, respectively, were isolated from underground organs Linum austriacum perenne. Two previously undescribed lignans, denominated linadiacin A (3 4), identified. In acidic...

10.1021/acs.jnatprod.2c00580 article EN Journal of Natural Products 2023-03-01

A comparative phytochemical study on the phenylethanoid glycoside (PhEG) composition of underground organs three Plantago species (P. lanceolata, P. major, and media) that fruit wall seed parts Forsythia suspensa F. europaea fruits was performed. The leaves these six cultivars hybrid × intermedia were also analyzed, demonstrating tissue-specific accumulation decomposition PhEGs. Our analyses confirmed significance selected tissues as new abundant sources valuable natural compounds. optimized...

10.3390/ijms22083880 article EN International Journal of Molecular Sciences 2021-04-09
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