A5005188903- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Maternal and fetal healthcare
- Intraperitoneal and Appendiceal Malignancies
- Endometriosis Research and Treatment
- Maternal and Perinatal Health Interventions
- Cancer Immunotherapy and Biomarkers
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and preeclampsia studies
- Angiogenesis and VEGF in Cancer
- Colorectal and Anal Carcinomas
- Vascular Tumors and Angiosarcomas
- Venous Thromboembolism Diagnosis and Management
- Gastric Cancer Management and Outcomes
- Reproductive Biology and Fertility
- Uterine Myomas and Treatments
- Occupational and environmental lung diseases
- Nutrition and Health in Aging
- Renal Diseases and Glomerulopathies
- Renal and related cancers
- Ubiquitin and proteasome pathways
- Vascular Procedures and Complications
- Intestinal and Peritoneal Adhesions
- Cerebrovascular and genetic disorders
- Galectins and Cancer Biology
National Defense Medical College Hospital
2017-2022
National Defense Medical College
2019-2021
Weatherford College
2021
Suzuki (Japan)
2021
Saitama Prefecture
2021
National Defence Medical Centre
2019
Beijing Obstetrics and Gynecology Hospital
2017
Sendai Medical Center
2014-2015
National Hospital Organization
2014-2015
Isolated torsion of the fallopian tube without an ovarian abnormality is uncommon event, with incidence approximately 1 in 1,500,000 females. occurs mostly reproductive-aged women, and thus extremely rare menopausal women pre-pubertal girls. In case 1, 63-year-old Japanese woman presented a 2-day history acute lower abdominal pain. Menopause occurred at 53 years age. Pelvic ultrasonography showed enlarged mass (73 × 47 mm) on right side her uterus. An urgent laparoscopy was performed based...
Recently, Bakri balloon (BBT) was effective for women with placenta previa to reduce hemorrhage. However, about 10% of needed receive an invasive strategy. Thus, the identification risk factors and development additional measurements BBT failure needed. The aim our study is investigate cause failing prophylactic in previa.Women who underwent cesarean section had a inserted during operation at institution between January 2015 December 2017 were enrolled. Patients requiring procedures after...
Abstract Background This study aimed to investigate the association between clinicopathologic factors, mesothelin, and cancer antigen (CA) 125 in endometrial carcinoma. Methods Between 1989 2017, patients with carcinoma who underwent total hysterectomy bilateral salpingo-oophorectomy at our hospital were identified. The either or both immunochemical expression of mesothelin CA125 clinicopathological features retrospectively examined. Results Among 485 patients, 171 positive for 368 CA125,...
Background/Aim: To investigate whether XIAP down-regulation and autophagy inhibition sensitize ovarian clear cell cancer cells to cisplatin. Materials Methods: The line KK was used for in vitro analysis. Hydroxychloroquine (HCQ) phenoxodiol (PXD) or embelin were as inhibitors, respectively. Non-specific XIAP-specific siRNAs transfected using Lipofectamine. Cytotoxicity assessed by MTT assays. Protein expression confirmed western blotting. Results: In KK, of specific together with HCQ...
Abstract Introduction Placenta previa with placenta accreta spectrum (PAS) is a life‐threatening disease that results in massive hemorrhage. The clinical and histologic criteria of PAS were adopted according to the International Federation Gynaecology Obstetrics (FIGO) classification. We aimed investigate whether FIGO topography associated maternal complications patients previa. Material methods Patients who underwent cesarean section at our institution between January 2003 December 2019...
Abstract Introduction Massive hemorrhage due to placenta previa with accreta spectrum is associated high maternal mortality and morbidity. Therefore, accurate prediction of essential; magnetic resonance imaging (MRI) a useful tool for this purpose. This study investigated novel predictors anterior posterior using MRI. Material methods was retrospective at tertiary obstetrics hospital in Japan. The singleton patients who were scanned MRI prenatally had cesarean section our institution between...
Aim: To examine the clinicopathological features of ovarian seromucinous borderline tumors (SMBTs) and compare them with those mucinous borderline/atypical proliferative (MB/APMTs). Patients Methods: SMBT between 2014 2018 MB/APMT 1988 who underwent surgery at our Institution were identified. Pathological review was conducted using World Health Organization criteria. Clinical compared retrospectively MB/APMT. Results: In total, 11 (12.9%) patients 74 (87.1%) included in study. The diagnosis...
Almost a quarter of century has passed since the term sarcopenia was defined. Sarcopenia is recognized as poor prognostic factor in variety cancer types. In ovarian cancer, it remains controversial whether affects prognosis and how should be evaluated. The present study aimed to evaluate association between volume psoas major muscle survival patients with epithelial cancer. Medical charts who received first‑line chemotherapy paclitaxel carboplatin at National Defense College Hospital...
The purpose of this study was to compare the clinical behavior several grades endometrioid carcinoma (EC) compared high-grade serous (HGSC), based on World Health Organization 2014 criteria.Clinicopathological features were between all EC and HGSC, HGSC either grade 1/2 or 3 EC.Sixty-five patients with 214 identified. Among EC, 56 displayed nine had EC. progression-free (PFS) overall (OS) survival better than those HGSC; however, PFS OS did not statistically differ HGSC. Grade but 3, a...
Solitary uterine metastases from extragenital cancers are very rare. Breast cancer is the most frequent primary site of metastasis to corpus, with invasive lobular carcinoma more likely spread gynecologic organs than ductal carcinoma. A 62-year-old postmenopausal Japanese woman was diagnosed leiomyomata 20 years ago and had been managed conservatively until menopause. Seven prior her presentation, she breast underwent a partial resection right for stage IIA She adjuvant chemotherapy,...
Abstract Background Ascites cytology is important for determining the stage and treatment methods ovarian clear cell carcinoma (CCC) as defined by 2014 International Federation of Obstetrics Gynecology classification. Methods Patients with CCC who underwent surgery at our hospital between January 2012 December 2019 received cytodiagnosis their ascites using Papanicolaou (Pap) May–Grünwald–Giemsa (MGG) staining, block were identified. The technique was performed hematoxylin‐eosin (H&E)...
The aim of this study was to evaluate the clinicopathological factors and prognosis mucinous carcinoma (MC) with infiltrative invasion, MC expansile high-grade serous (HGSC).Cases HGSC between 1984 2019 were identified. invasion or retrospectively compared. Although our present included cases in previous studies, we extended observational period when analysis performed. Accordingly, added increased survival newly conducted.After pathological review, 27 25 219 included. had a better terms...
To determine whether CD44, which is associated with tumor growth and metastasis, related to carcinogenesis prognosis in ovarian mucinous carcinomas (MACs).Tissue blocks from 71 patients benign tumors were used the study: 35 borderline tumors, 60 MACs. Immunochemical analysis was performed evaluate expression of CD44 examine its association tumorigenesis survival.Compared had high levels (p=0.047). Conversely, MACs lower than (p=0.032). Progression-free overall survival MAC low worse those...
Abstract Background Bevacizumab (Bev) plays the central role of adjuvant therapy for patients with ovarian carcinoma. The aim our study was to examine whether differences in administration Bev influence prognosis patients. Methods Patients carcinoma who received treatment at two hospitals between 1999 and 2020 were identified. treated weekly low-dose (100 mg on days 1 8 200 day 15, monthly) one hospital (group A) those monthly high-dose (15 mg/kg 1, another B) retrospectively compared....
The clinical significance of lymphocyte infiltration (LI) at the invasive front in endometrial carcinomas (EC) has not been determined. aim current study was to evaluate association between zone formation LI tumor margin and prognoses patients with EC.All available pathological slides enrolled cases were reviewed, degree categorized into 2 groups: strong weak LI. Clinical evaluated retrospectively.A total 333 EC study: 225 108 Weak more frequently observed grade1/2 endometrioid EC....
There is a similarity of histological features and survival between ovarian mucinous carcinoma (MC) with expansile invasion borderline tumor (MBT). The aim this study was to compare the clinical outcomes MC those MBT based on 2020 World Health Organization (WHO) criteria.A pathological review performed patients MC, MBT, seromucinous tumors that underwent surgery at our hospital 1984 2019. Clinicopathological were compared retrospectively MBT.Among 83 cases 85 12 tumor, 25 98 included through...